{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T18:21:57Z","timestamp":1777918917697,"version":"3.51.4"},"reference-count":13,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2010,9,22]],"date-time":"2010-09-22T00:00:00Z","timestamp":1285113600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Vet Pathol"],"published-print":{"date-parts":[[2011,7]]},"abstract":"<jats:p>The plant piquill\u00edn ( Condalia microphylla) grows in arid regions of Argentina and is the cause of mal del piquill\u00edn in cattle. The salient histologic features of this leukomyelopathy are vacuolation of white matter and axonal degeneration in the spinal cord. The histologic lesions can be experimentally reproduced in cattle and pigs by feeding milled bark of the plant, but naturally occurring piquill\u00edn toxicosis has not been reported previously in pigs. The authors report an outbreak of progressive ataxia on an Argentine hog farm, where partially consumed piquill\u00edn plants were found in the pens of affected pigs. Histologic lesions included vacuolation of white matter, edema, and mild axonal degeneration in lumbosacral segments of the cord. The diagnosis of mal del piquill\u00edn was based on the history, clinical signs, histologic changes, and elimination of other potential causes of leukomyelopathy. No new outbreaks developed after elimination of piquill\u00edn from the hog lots. Results of this investigation indicate that C microphylla toxicosis can affect pigs under natural conditions and should be included in the differential diagnosis for porcine ataxia and leukomyelopathy in regions where the plant grows.<\/jats:p>","DOI":"10.1177\/0300985810382513","type":"journal-article","created":{"date-parts":[[2010,9,23]],"date-time":"2010-09-23T00:25:34Z","timestamp":1285201534000},"page":"803-806","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["Outbreak of Ataxia in Pigs Associated With Consumption of Piquill\u00edn (\n                    <i>Condalia microphylla<\/i>\n                    )"],"prefix":"10.1177","volume":"48","author":[{"given":"F.","family":"Delgado","sequence":"first","affiliation":[{"name":"Instituto Nacional de Tecnolog\u00eda Agropecuaria, Buenos Aires, Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Burtre","sequence":"additional","affiliation":[{"name":"Instituto Nacional de Tecnolog\u00eda Agropecuaria, Buenos Aires, Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Capellino","sequence":"additional","affiliation":[{"name":"Instituto Nacional de Tecnolog\u00eda Agropecuaria, Buenos Aires, Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Salvat","sequence":"additional","affiliation":[{"name":"Instituto Nacional de Tecnolog\u00eda Agropecuaria, Buenos Aires, Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F. J.","family":"Blanco Viera","sequence":"additional","affiliation":[{"name":"Instituto Nacional de Tecnolog\u00eda Agropecuaria, Buenos Aires, Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2010,9,22]]},"reference":[{"key":"bibr1-0300985810382513","first-page":"251","volume":"23","author":"Bedotti D","year":"2006","journal-title":"Vet Arg"},{"key":"bibr2-0300985810382513","first-page":"777","volume-title":"Diseases of Swine","author":"Carson TL","year":"1992","edition":"7"},{"key":"bibr3-0300985810382513","volume-title":"Flora Patag\u00f3nica","author":"Correa MN","year":"1988"},{"key":"bibr4-0300985810382513","first-page":"255","volume":"88","author":"Delgado F","year":"2007","journal-title":"Med Vet (Buenos Aires)"},{"key":"bibr5-0300985810382513","doi-asserted-by":"publisher","DOI":"10.3390\/50300470"},{"key":"bibr6-0300985810382513","volume-title":"Manual of Staining Methods of the Armed Forces Institute of Pathology","author":"Luna LG","year":"1968"},{"key":"bibr7-0300985810382513","first-page":"327","volume":"26","author":"Marchesi E","year":"2004","journal-title":"Caldasia"},{"key":"bibr8-0300985810382513","first-page":"37","volume-title":"Jubb, Kennedy and Palmer\u2019s Pathology of Domestic Animals","volume":"3","author":"Maxie MG","year":"2007","edition":"5"},{"key":"bibr9-0300985810382513","first-page":"281","volume-title":"Jubb, Kennedy and Palmer\u2019s Pathology of Domestic Animals","volume":"1","author":"Maxie GM","year":"2007","edition":"5"},{"key":"bibr10-0300985810382513","doi-asserted-by":"publisher","DOI":"10.1016\/S0921-4488(99)00113-3"},{"key":"bibr11-0300985810382513","first-page":"251","volume-title":"El Libro Azul de las Micotoxicosis","author":"Smith T","year":"2008"},{"key":"bibr12-0300985810382513","first-page":"55","volume-title":"Jubb, Kennedy and Palmer\u2019s Pathology of Domestic Animals","volume":"1","author":"Thompson K","year":"2007","edition":"5"},{"key":"bibr13-0300985810382513","unstructured":"US Department of Agriculture: Plants Profile: Condalia Cav (Snakewood). http:\/\/plants.usda.gov\/java\/profile?symbol=CONDA. 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