{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T11:40:24Z","timestamp":1785498024701,"version":"3.56.0"},"reference-count":10,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2012,6,13]],"date-time":"2012-06-13T00:00:00Z","timestamp":1339545600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Vet Pathol"],"published-print":{"date-parts":[[2013,3]]},"abstract":"<jats:p>Cryptococcus neoformans var. grubii was identified at necropsy in a case of bilateral otitis interna in a 7-year-old, female, domestic shorthair cat with a 9-day history of acute onset of vestibular disease. Gross examination, including that of the middle and inner ears, was unremarkable. Histologically, the auricular vestibuli, cochleae, and semicircular canals were bilaterally affected by granulomatous inflammation with extracellular and intrahistiocytic yeasts. The yeasts and associated inflammation obstructed and disrupted perilymphatic and endolymphatic spaces of the inner ears. Disruption of the saccular and utricular maculae, cristae ampularis, and organ of Corti, as well as changes in the endolymphatic and perilymphatic fluids, probably impaired the vestibular and auditory functions of this cat. The route of infection was most likely hematogenous.<\/jats:p>","DOI":"10.1177\/0300985812451623","type":"journal-article","created":{"date-parts":[[2012,6,14]],"date-time":"2012-06-14T20:20:54Z","timestamp":1339705254000},"page":"260-263","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":12,"title":["Otitis Interna Induced by\n                    <i>Cryptococcus neoformans<\/i>\n                    var.\n                    <i>grubii<\/i>\n                    in a Cat"],"prefix":"10.1177","volume":"50","author":[{"given":"J.","family":"Paulin","sequence":"first","affiliation":[{"name":"Department of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, St. Paul, MN, USA"},{"name":"Current affiliation: Medtronic Physiological Research Laboratory, Minneapolis, MN, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Morshed","sequence":"additional","affiliation":[{"name":"BC Centre for Disease Control Public Health Microbiology and Reference Laboratory, Vancouver, British Columbia, Canada"},{"name":"Department of Pathology and Laboratory Medicine, University of British Columbia, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. G.","family":"Armi\u00e9n","sequence":"additional","affiliation":[{"name":"Department of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, St. Paul, MN, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2012,6,13]]},"reference":[{"key":"bibr1-0300985812451623","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-7216-6706-5.00012-3"},{"key":"bibr2-0300985812451623","first-page":"988","volume-title":"Miller\u2019s Anatomy of the Dog","author":"Evans HE","year":"1993","edition":"3"},{"key":"bibr3-0300985812451623","doi-asserted-by":"publisher","DOI":"10.1258\/ebm.2009.009281"},{"key":"bibr4-0300985812451623","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-1676.1997.tb00064.x"},{"key":"bibr5-0300985812451623","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1997.tb51885.x"},{"key":"bibr6-0300985812451623","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0402981101"},{"key":"bibr7-0300985812451623","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-323-07842-9.50013-7"},{"key":"bibr8-0300985812451623","first-page":"584","volume-title":"Infectious Diseases of the Dog and Cat","author":"Malik R","year":"2006","edition":"3"},{"key":"bibr9-0300985812451623","first-page":"425","volume-title":"Physiology and Pathology of Chloride Transporters and Channels in the Nervous System","author":"Marcus DC","year":"2009"},{"key":"bibr10-0300985812451623","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-1676.2010.0633.x"}],"container-title":["Veterinary Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0300985812451623","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0300985812451623","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0300985812451623","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T18:52:27Z","timestamp":1777661547000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0300985812451623"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,6,13]]},"references-count":10,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2013,3]]}},"alternative-id":["10.1177\/0300985812451623"],"URL":"https:\/\/doi.org\/10.1177\/0300985812451623","relation":{},"ISSN":["0300-9858","1544-2217"],"issn-type":[{"value":"0300-9858","type":"print"},{"value":"1544-2217","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,6,13]]}}}