{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T15:35:26Z","timestamp":1792856126055,"version":"4.5.0"},"reference-count":15,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2013,6,4]],"date-time":"2013-06-04T00:00:00Z","timestamp":1370304000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Vet Pathol"],"published-print":{"date-parts":[[2013,11]]},"abstract":"<jats:p>Squamous cell carcinoma represents 47.4% of all malignant canine digital lesions, but despite its frequency, there are few published studies available. Pathology submission records of 154 cases and follow-up of 49 animals were analyzed. On the 49 cases, histological evaluation was performed of the differentiation degree, mitotic index, presence of emboli, and immunohistochemical expression of vimentin and E-cadherin. The mean (SD) age of affected animals was 10.2 (2.3) years; no sex predisposition was recorded. Beauceron and Briard were 2 new overrepresented breeds. Dark-haired animals comprised 97 of 105 (92%); 94 dogs of 125 (75.2%) belonged to large and giant breeds. The forelimb was affected twice more than the hind limb. Probable metastases were observed in 4 dogs; new tumor development was recorded in 11 of 49 (22.4%). Epidemiologic factors, histological grade, mitotic index, and expression of immunohistochemical markers seemed not to be related to the clinical outcome.<\/jats:p>","DOI":"10.1177\/0300985813490757","type":"journal-article","created":{"date-parts":[[2013,6,5]],"date-time":"2013-06-05T01:54:10Z","timestamp":1370397250000},"page":"1078-1082","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":36,"title":["Digital Squamous Cell Carcinoma in Dogs"],"prefix":"10.1177","volume":"50","author":[{"given":"S.","family":"Belluco","sequence":"first","affiliation":[{"name":"Equipe recherche UPSP ICE 2011-03-101: Oncology, Vetagro-sup, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Brisebard","sequence":"additional","affiliation":[{"name":"Equipe recherche UPSP ICE 2011-03-101: Oncology, Vetagro-sup, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Watrelot","sequence":"additional","affiliation":[{"name":"Equipe recherche UPSP ICE 2011-03-101: Oncology, Vetagro-sup, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Pillet","sequence":"additional","affiliation":[{"name":"Equipe recherche UPSP ICE 2011-03-101: Oncology, Vetagro-sup, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.","family":"Marchal","sequence":"additional","affiliation":[{"name":"Equipe recherche UPSP ICE 2011-03-101: Oncology, Vetagro-sup, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Ponce","sequence":"additional","affiliation":[{"name":"Equipe recherche UPSP ICE 2011-03-101: Oncology, Vetagro-sup, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2013,6,4]]},"reference":[{"key":"bibr1-0300985813490757","author":"Biddle A","journal-title":"Cancer Metastasis Rev"},{"key":"bibr2-0300985813490757","doi-asserted-by":"publisher","DOI":"10.1177\/0300985810396105"},{"key":"bibr3-0300985813490757","first-page":"106","volume-title":"Histological Classification of Epithelial and Melanocytic Tumors of the Skin of Domestic Animals (WHO International Classification of Tumors of Domestic Animals)","author":"Goldschmidt MH","year":"1998"},{"key":"bibr4-0300985813490757","doi-asserted-by":"publisher","DOI":"10.1002\/9780470376928.ch2"},{"key":"bibr5-0300985813490757","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-5827.1998.tb03631.x"},{"key":"bibr6-0300985813490757","doi-asserted-by":"publisher","DOI":"10.1002\/jcp.21223"},{"key":"bibr7-0300985813490757","doi-asserted-by":"crossref","first-page":"932","DOI":"10.1002\/9780470752487","volume-title":"Skin Diseases of the Dog and Cat","author":"Lee Gross T","year":"2005"},{"key":"bibr8-0300985813490757","first-page":"411","volume":"153","author":"Liu SK","year":"1968","journal-title":"J Am Vet Med Assoc"},{"key":"bibr9-0300985813490757","doi-asserted-by":"publisher","DOI":"10.2460\/javma.1995.207.06.0726"},{"key":"bibr10-0300985813490757","doi-asserted-by":"publisher","DOI":"10.1016\/S0195-5616(97)50007-6"},{"key":"bibr11-0300985813490757","doi-asserted-by":"publisher","DOI":"10.2460\/javma.1992.201.05.759"},{"key":"bibr12-0300985813490757","doi-asserted-by":"publisher","DOI":"10.1136\/vr.125.12.322"},{"key":"bibr13-0300985813490757","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2407-7-124"},{"key":"bibr14-0300985813490757","doi-asserted-by":"publisher","DOI":"10.1093\/jb\/mvr044"},{"key":"bibr15-0300985813490757","doi-asserted-by":"publisher","DOI":"10.1354\/vp.44-3-355"}],"container-title":["Veterinary Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0300985813490757","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0300985813490757","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0300985813490757","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T18:53:36Z","timestamp":1777661616000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0300985813490757"}},"subtitle":["Epidemiological, Histological, and Imunohistochemical Study"],"short-title":[],"issued":{"date-parts":[[2013,6,4]]},"references-count":15,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2013,11]]}},"alternative-id":["10.1177\/0300985813490757"],"URL":"https:\/\/doi.org\/10.1177\/0300985813490757","relation":{},"ISSN":["0300-9858","1544-2217"],"issn-type":[{"value":"0300-9858","type":"print"},{"value":"1544-2217","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,6,4]]}}}