{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,12]],"date-time":"2026-06-12T18:21:10Z","timestamp":1781288470013,"version":"3.54.1"},"reference-count":12,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2017,8,16]],"date-time":"2017-08-16T00:00:00Z","timestamp":1502841600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Vet Pathol"],"published-print":{"date-parts":[[2017,11]]},"abstract":"<jats:p>A 12-year-old male Yorkshire Terrier was presented because of decreased appetite. Physical examination revealed mammary gland swelling and galactorrhea. Contrast-enhanced computed tomographic scanning of the skull indicated an enlarged pituitary gland, compatible with a pituitary tumor. The serum prolactin concentration was markedly elevated. One week after the start of treatment with the dopamine agonist cabergoline, the serum prolactin concentration normalized and the galactorrhea resolved. Cabergoline was administered for approximately 4 months and then discontinued. Subsequently, serum prolactin concentration increased again, and mammary gland swelling and galactorrhea reappeared. The dog was euthanized 10 months after the first detection of the galactorrhea because of problems not directly related to pituitary disease. Postmortem examination revealed an infiltrative adenoma of the pituitary gland with immunolabeling for prolactin. The clinical and histopathologic findings indicated the diagnosis of a functional prolactinoma in a male dog.<\/jats:p>","DOI":"10.1177\/0300985817726118","type":"journal-article","created":{"date-parts":[[2017,8,16]],"date-time":"2017-08-16T06:20:13Z","timestamp":1502864413000},"page":"972-976","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":9,"title":["Prolactinoma in a Dog"],"prefix":"10.1177","volume":"54","author":[{"given":"Cristina","family":"Cosio","sequence":"first","affiliation":[{"name":"Veterinary Clinic Croce di Gussago, Brescia, Italy"},{"name":"Contributed equally to this work."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena","family":"Sartori","sequence":"additional","affiliation":[{"name":"Veterinary Clinic Dr Luccardini Lorenzo, Pavia, Italy"},{"name":"Contributed equally to this work."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcello","family":"Garatti","sequence":"additional","affiliation":[{"name":"Veterinary Clinic S. Antonio, Sal\u00f2, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lorenzo","family":"Luccardini","sequence":"additional","affiliation":[{"name":"Veterinary Clinic Dr Luccardini Lorenzo, Pavia, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.C.M.","family":"Grinwis","sequence":"additional","affiliation":[{"name":"Department of Pathobiology, Faculty of Veterinary Medicine, Utrecht, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hans S.","family":"Kooistra","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences of Companion Animals, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Federico","family":"Fracassi","sequence":"additional","affiliation":[{"name":"Department of Veterinary Medical Sciences, University of Bologna, Bologna, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2017,8,16]]},"reference":[{"key":"bibr1-0300985817726118","doi-asserted-by":"publisher","DOI":"10.1530\/EJE-11-0076"},{"key":"bibr2-0300985817726118","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2003-032055"},{"key":"bibr3-0300985817726118","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-5827.1997.tb03322.x"},{"key":"bibr4-0300985817726118","doi-asserted-by":"publisher","DOI":"10.1016\/j.domaniend.2005.12.009"},{"key":"bibr5-0300985817726118","doi-asserted-by":"publisher","DOI":"10.1677\/joe.0.1520387"},{"key":"bibr6-0300985817726118","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2016.19699"},{"key":"bibr7-0300985817726118","doi-asserted-by":"publisher","DOI":"10.1016\/S0889-8529(05)70061-X"},{"key":"bibr8-0300985817726118","doi-asserted-by":"publisher","DOI":"10.1136\/vr.102263"},{"key":"bibr9-0300985817726118","doi-asserted-by":"publisher","DOI":"10.1210\/endo.134.1.7506206"},{"key":"bibr10-0300985817726118","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-1012383"},{"key":"bibr11-0300985817726118","doi-asserted-by":"publisher","DOI":"10.1016\/j.domaniend.2009.11.003"},{"key":"bibr12-0300985817726118","doi-asserted-by":"publisher","DOI":"10.2165\/00024677-200302010-00003"}],"container-title":["Veterinary Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0300985817726118","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0300985817726118","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0300985817726118","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T18:58:09Z","timestamp":1777661889000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0300985817726118"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,8,16]]},"references-count":12,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2017,11]]}},"alternative-id":["10.1177\/0300985817726118"],"URL":"https:\/\/doi.org\/10.1177\/0300985817726118","relation":{},"ISSN":["0300-9858","1544-2217"],"issn-type":[{"value":"0300-9858","type":"print"},{"value":"1544-2217","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,8,16]]}}}