{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T18:27:45Z","timestamp":1777919265867,"version":"3.51.4"},"reference-count":11,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2017,11,30]],"date-time":"2017-11-30T00:00:00Z","timestamp":1512000000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Vet Pathol"],"published-print":{"date-parts":[[2018,3]]},"abstract":"<jats:p>A 9-year-old female mixed breed dog presented for an acute onset of anorexia, vomiting, and cough. Initial examination and diagnostics revealed a large multilobular cranial mediastinal mass with unidentified fungal organisms on cytology. The disease progressed in spite of therapy until the dog was euthanized 8 months later. Gross necropsy findings were a large multilobular intrathoracic mass, mild pleuritis, and generalized lymphadenopathy. Histologic evaluation showed granulomatous inflammation and necrosis with numerous 20- to 70-micron, periodic acid\u2013Schiff- and Gomori methenamine silver-positive spherules effacing lymph node parenchyma, as well as severe inflammation within the midbrain. Endosporulation was a common finding, and large numbers of fungal hyphae were also present in affected areas. Ribosomal RNA gene sequencing found 100% identity to published sequences of Phanerochaete chrysosporium, the teleomorph form of Sporotrichum pruinosum. This is the first published report of disease caused by natural infection with this basidiomycete organism in animals.<\/jats:p>","DOI":"10.1177\/0300985817741731","type":"journal-article","created":{"date-parts":[[2017,11,30]],"date-time":"2017-11-30T21:52:45Z","timestamp":1512078765000},"page":"298-302","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["Severe Disseminated Necrotizing and Granulomatous Lymphadenitis and Encephalitis in a Dog Due to\n                    <i>Sporotrichum pruinosum<\/i>\n                    (Teleomorph:\n                    <i>Phanerochaete chrysosporium<\/i>\n                    )"],"prefix":"10.1177","volume":"55","author":[{"given":"Drew R.","family":"Magstadt","sequence":"first","affiliation":[{"name":"Department of Veterinary Diagnostic and Production Animal Medicine, Iowa State University College of Veterinary Medicine, Ames, IA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amanda J.","family":"Fales-Williams","sequence":"additional","affiliation":[{"name":"Department of Veterinary Pathology, Iowa State University College of Veterinary Medicine, Ames, IA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean-S\u00e9bastien","family":"Palerme","sequence":"additional","affiliation":[{"name":"Department of Veterinary Clinical Sciences, Iowa State University College of Veterinary Medicine, Ames, IA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Heather","family":"Flaherty","sequence":"additional","affiliation":[{"name":"Department of Veterinary Pathology, Iowa State University College of Veterinary Medicine, Ames, IA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tracy","family":"Lindquist","sequence":"additional","affiliation":[{"name":"Department of Veterinary Pathology, Iowa State University College of Veterinary Medicine, Ames, IA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kristina G.","family":"Miles","sequence":"additional","affiliation":[{"name":"Department of Veterinary Clinical Sciences, Iowa State University College of Veterinary Medicine, Ames, IA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2017,11,30]]},"reference":[{"key":"bibr1-0300985817741731","doi-asserted-by":"publisher","DOI":"10.3109\/13693780902962267"},{"key":"bibr2-0300985817741731","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcpa.2014.04.015"},{"key":"bibr3-0300985817741731","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-165X.2012.00447.x"},{"key":"bibr4-0300985817741731","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.40.9.3535-3537.2002"},{"key":"bibr5-0300985817741731","doi-asserted-by":"publisher","DOI":"10.1080\/02681218880000221"},{"issue":"1","key":"bibr6-0300985817741731","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1002\/rcr2.31","volume":"2","author":"Lanspa MJ","year":"2014","journal-title":"Respirol Case Rep"},{"key":"bibr7-0300985817741731","doi-asserted-by":"publisher","DOI":"10.1177\/1040638711425944"},{"key":"bibr8-0300985817741731","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvc.2015.01.004"},{"key":"bibr9-0300985817741731","doi-asserted-by":"publisher","DOI":"10.1016\/j.mjafi.2014.11.011"},{"key":"bibr10-0300985817741731","doi-asserted-by":"publisher","DOI":"10.1177\/1040638713499341"},{"key":"bibr11-0300985817741731","doi-asserted-by":"publisher","DOI":"10.1007\/s00253-008-1706-9"}],"container-title":["Veterinary Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0300985817741731","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0300985817741731","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0300985817741731","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T18:58:19Z","timestamp":1777661899000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0300985817741731"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,11,30]]},"references-count":11,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2018,3]]}},"alternative-id":["10.1177\/0300985817741731"],"URL":"https:\/\/doi.org\/10.1177\/0300985817741731","relation":{},"ISSN":["0300-9858","1544-2217"],"issn-type":[{"value":"0300-9858","type":"print"},{"value":"1544-2217","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,11,30]]}}}