{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T18:28:08Z","timestamp":1777919288921,"version":"3.51.4"},"reference-count":34,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2019,1,27]],"date-time":"2019-01-27T00:00:00Z","timestamp":1548547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Vet Pathol"],"published-print":{"date-parts":[[2019,5]]},"abstract":"<jats:p>Thirty-seven adult female moose ( Alces alces) from 2 distinct but adjacent populations in Elk Island National Park (EINP), Alberta, Canada (19 in north EINP and 18 in south EINP), were fitted with mortality-sensing VHF radio-collars, and radio signals were acquired daily to ascertain mortality status. At capture, serum, whole blood, and feces were collected; pregnancy was determined; teeth were aged by visual inspection; and a portion of liver was assessed by ultrasound examination. Postmortem examination was conducted on 20 suitable carcasses. Clinical pathological abnormalities, including eosinophilia, polycythemia, elevated levels of liver enzymes in serum, hemoglobin, hematocrit, and red blood cell distribution, and liver damage as seen in ultrasound images occurred only in moose from north EINP. Infected moose had 4.7 \u00b1 4.8 Fascioloides magna flukes per liver (mean \u00b1 SD). The proportion of moose pregnant at capture was similar in both populations (74% in north EINP, 61% in south EINP). Proportional mortality was significantly higher in moose from the north (68%) than the south (32%). Fascioloides magna was associated as a cause of death in 7 of 14 (50%) moose in the north where cause of death was determined, while predation ( n = 1), acute toxemic syndrome ( n = 3), dystocia ( n = 1), and roadkill and undetermined causes ( n = 3) were additional causes of mortality. F. magna was associated with poor body condition and was a major cause of mortality in north EINP but not south EINP, despite very similar habitat and proximity, suggesting a significant role for these flukes in affecting health and viability of naturally infected moose populations.<\/jats:p>","DOI":"10.1177\/0300985818823776","type":"journal-article","created":{"date-parts":[[2019,1,28]],"date-time":"2019-01-28T00:07:11Z","timestamp":1548634031000},"page":"476-485","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":14,"title":["<i>Fascioloides magna<\/i>\n                    in Moose (\n                    <i>Alces alces<\/i>\n                    ) From Elk Island National Park, Alberta"],"prefix":"10.1177","volume":"56","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8410-4226","authenticated-orcid":false,"given":"Todd K.","family":"Shury","sequence":"first","affiliation":[{"name":"Parks Canada Agency, Saskatoon, Saskatchewan, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Margo J.","family":"Pybus","sequence":"additional","affiliation":[{"name":"Alberta Fish and Wildlife Division, Edmonton, Alberta, Canada"},{"name":"Department of Biological Sciences, University of Alberta, Edmonton, Alberta, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0501-6936","authenticated-orcid":false,"given":"Nick","family":"Nation","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine and Pathology, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Normand L.","family":"Cool","sequence":"additional","affiliation":[{"name":"121 Galloway Park, Fort Saskatchewan, Alberta, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W. James","family":"Rettie","sequence":"additional","affiliation":[{"name":"Paragon Research and Analysis Ltd., Winnipeg, Manitoba, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2019,1,27]]},"reference":[{"key":"bibr1-0300985818823776","doi-asserted-by":"publisher","DOI":"10.7557\/2.15.1.1153"},{"key":"bibr2-0300985818823776","volume-title":"A Plan for the Management of Vegetation and Ungulates","author":"Blyth CB","year":"1987"},{"issue":"11","key":"bibr3-0300985818823776","first-page":"1255","volume":"18","author":"Braun U","year":"1996","journal-title":"Compend Contin Educ Pract Vet"},{"key":"bibr4-0300985818823776","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9975(08)80077-1"},{"key":"bibr5-0300985818823776","doi-asserted-by":"publisher","DOI":"10.1139\/cjr46d-007"},{"key":"bibr6-0300985818823776","first-page":"706","volume":"141","author":"Cox DD","year":"1962","journal-title":"J Am Vet Med Assoc"},{"key":"bibr7-0300985818823776","unstructured":"Fenstermacher R, Olsen OW. Further studies of diseases affecting moose, III. 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Giant Liver Fluke\n                      (\n                      Fascioloides magna\n                      )\n                      , an Important Liver Parasite of Ruminants. 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