{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T01:57:24Z","timestamp":1783475844742,"version":"3.55.0"},"reference-count":38,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2020,2,25]],"date-time":"2020-02-25T00:00:00Z","timestamp":1582588800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Vet Pathol"],"published-print":{"date-parts":[[2020,5]]},"abstract":"<jats:p>This is a histopathologic and endocrinologic study of 6 calves diagnosed with cryptorchidism. Cases 1\u20133 were diagnosed as resembling testicular regression syndrome. In cases 1 and 2, the extracted tissue was a small, firm, gray-white mass, and there was lack of obvious testicular tissue in case 3. Histopathologically, the excised tissue in cases 1\u20133 was a fibrotic testicular remnant with inflammation, mineralization, hemosiderin-laden macrophages or lipofuscin-laden macrophages, and lack of germ cells and interstitial endocrine cells. These findings were compared with cases 4\u20136, which were diagnosed as testicular hypoplasia due to cryptorchidism. These cases had small but otherwise grossly unremarkable intra-abdominal testicular tissue and histologically had a few germ cells and sustentacular cells with arrested spermatogenesis and an increase in interstitial endocrine cells. Cases 1\u20133 had more severe degenerative changes compared with cases 4\u20136. In case 2, the average diameter of the seminiferous tubules was much smaller than in cases 4\u20136, and there were few tubule cross sections. Anti-M\u00fcllerian hormone (214 pg\/ml) was detected in the plasma of case 2. Based on the macroscopic and histopathologic findings as well as endocrinologic profiles, the testicular degeneration in cases 1\u20133 was considered similar to that of testicular regression syndrome. In this condition, it is thought that a normally developing intra-abdominal testis undergoes degeneration due to heat or a vascular disorder such as torsion.<\/jats:p>","DOI":"10.1177\/0300985820906891","type":"journal-article","created":{"date-parts":[[2020,2,25]],"date-time":"2020-02-25T06:22:43Z","timestamp":1582611763000},"page":"418-426","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":7,"title":["Severe Degenerative Changes in Cryptorchid Testes in Japanese Black Cattle"],"prefix":"10.1177","volume":"57","author":[{"given":"Naoyuki","family":"Fuke","sequence":"first","affiliation":[{"name":"Department of Veterinary Pathology, Faculty of Agriculture, University of Miyazaki, Miyazaki, Japan"},{"name":"These authors contributed equally to this work."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Go","family":"Kitahara","sequence":"additional","affiliation":[{"name":"Department of Theriogenology, Faculty of Agriculture, University of Miyazaki, Miyazaki, Japan"},{"name":"These authors contributed equally to this work."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Soma","family":"Ito","sequence":"additional","affiliation":[{"name":"Department of Veterinary Pathology, Faculty of Agriculture, University of Miyazaki, Miyazaki, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nguyen","family":"Van Diep","sequence":"additional","affiliation":[{"name":"Department of Veterinary Pathology, Faculty of Agriculture, University of Miyazaki, Miyazaki, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angeline Ping","family":"Ping Teh","sequence":"additional","affiliation":[{"name":"Department of Veterinary Pathology, Faculty of Agriculture, University of Miyazaki, Miyazaki, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6635-7561","authenticated-orcid":false,"given":"Uda 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