{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T02:06:30Z","timestamp":1787018790350,"version":"build-2736575974"},"reference-count":20,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2023,3,4]],"date-time":"2023-03-04T00:00:00Z","timestamp":1677888000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Vet Pathol"],"published-print":{"date-parts":[[2023,5]]},"abstract":"<jats:p>Pituitary tumors are rare in chinchillas. This report describes the clinical, gross, histologic, and immunohistochemical characteristics of pituitary tumors in 4 chinchillas. The affected chinchillas were females between 4 and 18 years of age. Clinically, neurologic signs were most commonly reported and included depression, obtundation, seizure, head-pressing, ataxia, and possible blindness. Computed tomography scanning of 2 chinchillas revealed solitary intracranial extra-axial masses in the region of the pituitary gland. Two pituitary tumors were confined to the pars distalis; the other 2 invaded the brain. Based on their microscopic appearances and lack of distant metastases, all 4 tumors were diagnosed as pituitary adenomas. Immunohistochemically, all pituitary adenomas were weakly to strongly positive for growth hormone, most consistent with the diagnosis of somatotropic pituitary adenomas. To the authors\u2019 knowledge, this is the first detailed report of the clinical, pathologic, and immunohistochemical features of pituitary tumors in chinchillas.<\/jats:p>","DOI":"10.1177\/03009858231158077","type":"journal-article","created":{"date-parts":[[2023,3,4]],"date-time":"2023-03-04T07:43:27Z","timestamp":1677915807000},"page":"320-323","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":6,"title":["Clinical, pathologic, and immunohistochemical features of pituitary tumors in 4 chinchillas"],"prefix":"10.1177","volume":"60","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6105-0317","authenticated-orcid":false,"given":"Laura M.","family":"Lee","sequence":"first","affiliation":[{"name":"Auburn University College of Veterinary Medicine, Auburn, AL"},{"name":"University of Wisconsin\u2013Madison, Madison, WI"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Gasper","sequence":"additional","affiliation":[{"name":"University of Wisconsin\u2013Madison, Madison, WI"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zoltan","family":"Szabo","sequence":"additional","affiliation":[{"name":"Tai Wai Small Animal and Exotic Hospital, Hong Kong SAR, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"May","family":"Tse","sequence":"additional","affiliation":[{"name":"City University of Hong Kong Veterinary Diagnostic Laboratory, Hong Kong SAR, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shawna","family":"Hawkins","sequence":"additional","affiliation":[{"name":"University of Wisconsin\u2013Madison, Madison, WI"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Howard","family":"Steinberg","sequence":"additional","affiliation":[{"name":"University of Wisconsin\u2013Madison, Madison, WI"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matti","family":"Kiupel","sequence":"additional","affiliation":[{"name":"Michigan State University, East Lansing, MI"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2023,3,4]]},"reference":[{"key":"bibr1-03009858231158077","doi-asserted-by":"publisher","DOI":"10.1007\/s12022-022-09703-7"},{"key":"bibr2-03009858231158077","doi-asserted-by":"publisher","DOI":"10.1053\/j.jepm.2017.12.002"},{"key":"bibr3-03009858231158077","doi-asserted-by":"publisher","DOI":"10.1053\/j.jepm.2019.05.001"},{"key":"bibr4-03009858231158077","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcpa.2014.02.006"},{"key":"bibr5-03009858231158077","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcpa.2011.08.002"},{"key":"bibr6-03009858231158077","doi-asserted-by":"publisher","DOI":"10.1016\/j.cvex.2016.07.006"},{"key":"bibr7-03009858231158077","first-page":"310","volume":"46","author":"Konell AL","year":"2018","journal-title":"Acta Sci Vet"},{"key":"bibr8-03009858231158077","doi-asserted-by":"publisher","DOI":"10.1177\/0300985811419530"},{"key":"bibr9-03009858231158077","doi-asserted-by":"publisher","DOI":"10.1177\/1040638712446630"},{"key":"bibr10-03009858231158077","doi-asserted-by":"publisher","DOI":"10.1016\/B978-1-4160-6621-7.00024-5"},{"key":"bibr11-03009858231158077","doi-asserted-by":"publisher","DOI":"10.1016\/j.cvex.2020.01.005"},{"key":"bibr12-03009858231158077","doi-asserted-by":"publisher","DOI":"10.2460\/javma.239.5.656"},{"key":"bibr13-03009858231158077","unstructured":"Mete O. Pituitary gland: introduction. In: WHO Classification of Tumours Editorial Board. Endocrine and Neuroendocrine Tumours (WHO Classification of Tumours Series, 5th ed.; Vol. 10). Lyon, France: International Agency for Research on Cancer; 2022. Accessed January 18, 2023. https:\/\/tumourclassification.iarc.who.int\/chapters\/53."},{"key":"bibr14-03009858231158077","unstructured":"Mete O, Perry A, Lopes MBS, et al Pituitary gland: somatotroph PitNET\/adenoma. In: WHO Classification of Tumours Editorial Board. Endocrine and Neuroendocrine Tumours (WHO Classification of Tumours Series, 5th ed.; Vol. 10). Lyon, France: International Agency for Research on Cancer; 2022. Accessed January 18, 2023. https:\/\/tumourclassification.iarc.who.int\/chapters\/53."},{"key":"bibr15-03009858231158077","doi-asserted-by":"publisher","DOI":"10.1002\/9781119181200.ch18"},{"key":"bibr16-03009858231158077","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-443-06982-6.00018-3"},{"key":"bibr17-03009858231158077","doi-asserted-by":"publisher","DOI":"10.1177\/1098612X13483461"},{"key":"bibr18-03009858231158077","doi-asserted-by":"publisher","DOI":"10.1177\/104063871002200134"},{"key":"bibr19-03009858231158077","doi-asserted-by":"publisher","DOI":"10.1053\/j.jepm.2018.01.006"},{"key":"bibr20-03009858231158077","doi-asserted-by":"publisher","DOI":"10.1292\/jvms.18-0517"}],"container-title":["Veterinary Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/03009858231158077","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/03009858231158077","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/03009858231158077","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T19:03:58Z","timestamp":1777662238000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/03009858231158077"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,3,4]]},"references-count":20,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2023,5]]}},"alternative-id":["10.1177\/03009858231158077"],"URL":"https:\/\/doi.org\/10.1177\/03009858231158077","relation":{},"ISSN":["0300-9858","1544-2217"],"issn-type":[{"value":"0300-9858","type":"print"},{"value":"1544-2217","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,3,4]]}}}