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Affected reindeer displayed abnormal behavior, neurologic signs, lethargy, and\/or lameness. The most consistent gross finding was dark red streaks throughout the adrenal gland cortices (4\/4). One animal had acute hemorrhage involving the subcutis and skeletal muscles over the ventrolateral body wall and back, and abomasal serosa. Histologically, the most common lesions were adrenal gland cortical hemorrhage (4\/4) with necrosis (3\/4) and lymphoplasmacytic meningoencephalitis with gliosis, glial nodules, satellitosis, and nonsuppurative perivascular cuffing (4\/4). The brain lesions were most frequent in the gray matter of the cerebrum, hippocampus, and thalamus but also involved the cerebellum and brainstem. Epizootic hemorrhagic disease virus serotype 6 was detected through PCR and sequencing of the spleen in all cases.<\/jats:p>","DOI":"10.1177\/03009858231196797","type":"journal-article","created":{"date-parts":[[2023,8,31]],"date-time":"2023-08-31T04:37:29Z","timestamp":1693456649000},"page":"298-302","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Outbreak of epizootic hemorrhagic disease in captive reindeer (\n                    <i>Rangifer tarandus<\/i>\n                    )"],"prefix":"10.1177","volume":"61","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1917-1593","authenticated-orcid":false,"given":"Emma H.","family":"Torii","sequence":"first","affiliation":[{"name":"University of Minnesota, St. Paul, MN"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4292-4896","authenticated-orcid":false,"given":"Arno","family":"W\u00fcnschmann","sequence":"additional","affiliation":[{"name":"University of Minnesota, St. Paul, MN"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mia Kim","family":"Torchetti","sequence":"additional","affiliation":[{"name":"US Department of Agriculture, Ames, IA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leo","family":"Koster","sequence":"additional","affiliation":[{"name":"US Department of Agriculture, Ames, IA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Albert","family":"van Geelen","sequence":"additional","affiliation":[{"name":"US Department of Agriculture, Ames, IA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Randy","family":"Atchison","sequence":"additional","affiliation":[{"name":"US Department of Agriculture, Ames, IA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne","family":"Rivas","sequence":"additional","affiliation":[{"name":"Minnesota Zoo, Apple Valley, MN"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2023,8,31]]},"reference":[{"key":"bibr1-03009858231196797","doi-asserted-by":"publisher","DOI":"10.1099\/vir.0.015651-0"},{"key":"bibr2-03009858231196797","unstructured":"Centers for Disease Control and Prevention. 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