{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T18:32:20Z","timestamp":1777919540978,"version":"3.51.4"},"reference-count":18,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2024,8,15]],"date-time":"2024-08-15T00:00:00Z","timestamp":1723680000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Vet Pathol"],"published-print":{"date-parts":[[2025,7]]},"abstract":"<jats:p>\n                    Polyglucosan bodies are accumulations of insoluble glucose polymers and proteins that form intracytoplasmic inclusions in the brain, large numbers of which can be indicative of neurodegenerative diseases such as Lafora disease. Montserrat orioles (\n                    <jats:italic toggle=\"yes\">Icterus oberi<\/jats:italic>\n                    ) are an icterid passerine endemic to Montserrat with conservation populations maintained in captivity abroad. We demonstrate that polyglucosan bodies are unusually abundant in the cerebellar molecular and Purkinje cell layers and cerebellar peduncles of captive-bred and wild-caught Montserrat orioles. The bodies are periodic acid-Schiff positive and diastase resistant and label with concanavalin A and for ubiquitin, consistent with those seen in humans. We found no association of the polyglucosan bodies with concurrent neurological lesions or clinical signs, nor with\n                    <jats:italic toggle=\"yes\">EPM2<\/jats:italic>\n                    A and\n                    <jats:italic toggle=\"yes\">EPM2B<\/jats:italic>\n                    gene mutations associated with Lafora disease. We conclude that an abundance of cerebellar polyglucosan bodies may be a normal finding in aged Montserrat orioles and not a threat to the captive breeding population.\n                  <\/jats:p>","DOI":"10.1177\/03009858241270000","type":"journal-article","created":{"date-parts":[[2024,8,15]],"date-time":"2024-08-15T04:03:58Z","timestamp":1723694638000},"page":"581-585","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Incidence and characterization of polyglucosan bodies in the cerebella of montserrat orioles (\n                    <i>Icterus oberi<\/i>\n                    )"],"prefix":"10.1177","volume":"62","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9621-2192","authenticated-orcid":false,"given":"Simon","family":"Spiro","sequence":"first","affiliation":[{"name":"Zoological Society of London, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marta","family":"Pereira","sequence":"additional","affiliation":[{"name":"University of Nottingham, Nottingham, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kieran A.","family":"Bates","sequence":"additional","affiliation":[{"name":"Queen Mary University of London, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zane","family":"Jaunmuktane","sequence":"additional","affiliation":[{"name":"National Hospital for Neurology and Neurosurgery, University College London NHS Foundation Trust, London, UK"},{"name":"University College London, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David J.","family":"Everest","sequence":"additional","affiliation":[{"name":"Animal and Plant Health Agency, Weybridge, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark F.","family":"Stidworthy","sequence":"additional","affiliation":[{"name":"International Zoo Veterinary Group Pathology, Keighley, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniela","family":"Denk","sequence":"additional","affiliation":[{"name":"International Zoo Veterinary Group Pathology, Keighley, UK"},{"name":"SeaWorld Yas Island, Abu Dhabi, UAE"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alejandro","family":"N\u00fa\u00f1ez","sequence":"additional","affiliation":[{"name":"Animal and Plant Health Agency, Weybridge, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ethan","family":"Wrigglesworth","sequence":"additional","affiliation":[{"name":"Zoological Society of London, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew","family":"Theodoulou","sequence":"additional","affiliation":[{"name":"National Hospital for Neurology and Neurosurgery, University College London NHS Foundation Trust, London, UK"},{"name":"University College London, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alberto","family":"Barbon","sequence":"additional","affiliation":[{"name":"Jersey Zoo, Trinity, Jersey"},{"name":"Chester Zoo, Chester, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emma","family":"Nye","sequence":"additional","affiliation":[{"name":"The Francis Crick Institute, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yan","family":"Liu","sequence":"additional","affiliation":[{"name":"Imperial College London, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adrian L.","family":"Smith","sequence":"additional","affiliation":[{"name":"University of Oxford, Oxford, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steven","family":"Fiddaman","sequence":"additional","affiliation":[{"name":"University of Oxford, Oxford, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2024,8,15]]},"reference":[{"key":"e_1_3_3_2_2","unstructured":"BirdLife International. Species factsheet: Montserrat Oriole Icterus oberi. 2024. https:\/\/datazone.birdlife.org\/species\/factsheet\/montserrat-oriole-icterus-oberi"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-0173(99)00003-X"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1177\/0300985818758471"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00965562"},{"key":"e_1_3_3_6_2","doi-asserted-by":"crossref","unstructured":"Galli R Meinhardt M Koch E et al. 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