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Characterization of lesions in animal brucellosis remains paramount in the diagnosis in endemic regions and even for countries free of brucellosis, where passive surveillance plays an indispensable role in upholding and sustaining their status. Pathology also contributes to understanding the pathogenesis and associating emerging pathogenic\n                    <jats:italic toggle=\"yes\">Brucella<\/jats:italic>\n                    spp. with disease in animals. Here, we review the pathology of brucellosis in animals with an emphasis on cross-species transmission of \u201cclassical\u201d\n                    <jats:italic toggle=\"yes\">Brucella<\/jats:italic>\n                    spp. to nonpreferential hosts and \u201catypical\u201d\n                    <jats:italic toggle=\"yes\">Brucella<\/jats:italic>\n                    spp. We conclude that\n                    <jats:italic toggle=\"yes\">Brucella<\/jats:italic>\n                    is an expansive genus identified in numerous animals, but there are still significant gaps in the knowledge of the pathology of brucellosis in unusual hosts and emerging\n                    <jats:italic toggle=\"yes\">Brucella<\/jats:italic>\n                    spp. This is a great opportunity for veterinary pathologists to spearhead advancements in the knowledge of the pathogenesis and diagnosis of\n                    <jats:italic toggle=\"yes\">Brucella<\/jats:italic>\n                    spp. infections. The isolation of a\n                    <jats:italic toggle=\"yes\">Brucella<\/jats:italic>\n                    spp. and the correlation with lesions should follow molecular diagnostics to define the genetic signature of the isolate, providing a better understanding of epidemiology and contributing to the control of brucellosis across animal and human populations.\n                  <\/jats:p>","DOI":"10.1177\/03009858261435106","type":"journal-article","created":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T00:32:42Z","timestamp":1775781162000},"page":"787-806","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Pathology and diagnosis of brucellosis (\n                    <i>Brucella<\/i>\n                    spp.) in veterinary species"],"prefix":"10.1177","volume":"63","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4304-2713","authenticated-orcid":false,"given":"Agust\u00edn","family":"Rebollada-Merino","sequence":"first","affiliation":[{"name":"Cornell University, Ithaca, NY"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucas","family":"Dom\u00ednguez","sequence":"additional","affiliation":[{"name":"Complutense University of Madrid, Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Rodr\u00edguez-Bertos","sequence":"additional","affiliation":[{"name":"Complutense University of Madrid, Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,4,9]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00402559"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.onehlt.2024.100712"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.actatropica.2025.107521"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cimid.2020.101554"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetmic.2013.01.023"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1038\/srep44420"},{"key":"e_1_3_2_8_2","first-page":"1","article-title":"Scientific Opinion of the Panel on Animal Health and Welfare (AHAW) on a request from the commission on porcine brucellosis (Brucella suis)","volume":"1144","author":"Algers B","year":"2009","unstructured":"Algers B, Blokhuis HJ, B\u00f8tner A, et al. 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