{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T07:28:13Z","timestamp":1793518093678,"version":"4.5.0"},"reference-count":16,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T00:00:00Z","timestamp":1782432000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"National Institute of Agricultural Technology"},{"name":"Asociaci\u00f3n Cooperadora INTA Balcarce"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Vet Pathol"],"published-print":{"date-parts":[[2026,11]]},"abstract":"<jats:p>\n                    The ingestion of the pollen beetle\n                    <jats:italic toggle=\"yes\">Astylus atromaculatus<\/jats:italic>\n                    causes gastroenteric disease in ruminants and possibly in other species. No toxic principle has been identified in these insects. Two studies were conducted to evaluate the effects of oral administration of\n                    <jats:italic toggle=\"yes\">A. atromaculatus<\/jats:italic>\n                    in guinea pigs using fresh insects (\n                    <jats:italic toggle=\"yes\">n<\/jats:italic>\n                    = 3) and insects dried for different periods (2, 30, 60, 120, or 240 days) (\n                    <jats:italic toggle=\"yes\">n<\/jats:italic>\n                    = 5). All animals became sick and died spontaneously between 10 and 96 hours after inoculation. Clinical signs included depression; reluctance to move, eat, and drink; kyphosis; and increased frequency of vocalization, with no differences observed between the 2 experiments. Gross and microscopic findings consisted of diffuse ulcerative, fibrinonecrotizing, and hemorrhagic enteritis. No differences were observed in the type or severity of lesions between the 2 experiments or in animals inoculated with beetles dried for different durations. No clinical signs or lesions were observed in guinea pigs from the control group (\n                    <jats:italic toggle=\"yes\">n<\/jats:italic>\n                    = 2). This study adds to the knowledge of\n                    <jats:italic toggle=\"yes\">A. atromaculatus-<\/jats:italic>\n                    associated fatal gastroenteric disease in non-ruminants and highlights the persistent harmful effects of dried pollen beetles.\n                  <\/jats:p>","DOI":"10.1177\/03009858261461767","type":"journal-article","created":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T13:10:31Z","timestamp":1782479431000},"page":"1115-1120","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Fatal enteric disease reproduced in guinea pigs by oral administration of pollen beetle (\n                    <i>Astylus atromaculatus<\/i>\n                    )"],"prefix":"10.1177","volume":"63","author":[{"given":"Maria F.","family":"Ovelar","sequence":"first","affiliation":[{"name":"Instituto de Innovaci\u00f3n para la Producci\u00f3n Agropecuaria y el Desarrollo Sostenible (IPADS, INTA-CONICET), Balcarce, Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0681-1878","authenticated-orcid":false,"given":"Francisco A.","family":"Uzal","sequence":"additional","affiliation":[{"name":"University of California, Davis, San Bernardino, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3494-8193","authenticated-orcid":false,"given":"German J.","family":"Canton","sequence":"additional","affiliation":[{"name":"Instituto de Innovaci\u00f3n para la Producci\u00f3n Agropecuaria y el Desarrollo Sostenible (IPADS, INTA-CONICET), Balcarce, Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicolas","family":"Casamayouret","sequence":"additional","affiliation":[{"name":"Instituto de Innovaci\u00f3n para la Producci\u00f3n Agropecuaria y el Desarrollo Sostenible (IPADS, INTA-CONICET), Balcarce, Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan","family":"Poo","sequence":"additional","affiliation":[{"name":"Instituto de Innovaci\u00f3n para la Producci\u00f3n Agropecuaria y el Desarrollo Sostenible (IPADS, INTA-CONICET), Balcarce, Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8799-6848","authenticated-orcid":false,"given":"Federico","family":"Giannitti","sequence":"additional","affiliation":[{"name":"Instituto Nacional de Investigaci\u00f3n Agropecuaria (INIA), Colonia, Uruguay"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carolina","family":"Matto","sequence":"additional","affiliation":[{"name":"Ministerio de Ganader\u00eda, Agricultura y Pesca (MGAP) DILAVE \u201cMiguel C. Rubino,\u201d Paysand\u00fa, Uruguay"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan","family":"Livio","sequence":"additional","affiliation":[{"name":"Instituto de Innovaci\u00f3n para la Producci\u00f3n Agropecuaria y el Desarrollo Sostenible (IPADS, INTA-CONICET), Balcarce, Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8047-6724","authenticated-orcid":false,"given":"Juan A.","family":"Garcia","sequence":"additional","affiliation":[{"name":"Instituto de Innovaci\u00f3n para la Producci\u00f3n Agropecuaria y el Desarrollo Sostenible (IPADS, INTA-CONICET), Balcarce, Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,6,26]]},"reference":[{"key":"e_1_3_3_2_2","volume-title":"Gu\u00eda de insectos y \u00e1caros de importancia agr\u00edcola y forestal en el Uruguay","author":"Bentancourt CM, Scatoni IB","year":"2010","unstructured":"Bentancourt CM, Scatoni IB. Gu\u00eda de insectos y \u00e1caros de importancia agr\u00edcola y forestal en el Uruguay [Guide of Insects and Mites of Importance in Agriculture and Forestry in Uruguay]. 3rd ed. Facultad de Agronom\u00eda, Universidad de la Rep\u00fablica Oriental del Uruguay; 2010 (in Spanish).","edition":"3"},{"key":"e_1_3_3_3_2","volume-title":"Cat\u00e1logo de los insectos fit\u00f3fagos de la Argentina y sus plantas asociadas","author":"Di Iorio OR","year":"2004","unstructured":"Di Iorio OR. Melyridae. In: Cordo HA, Logarzo G, Braun K, et al, eds. Cat\u00e1logo de los insectos fit\u00f3fagos de la Argentina y sus plantas asociadas [Catalogue of Phytophagous Insects of Argentina and Their Associated Plants]. Sociedad Entomol\u00f3gica Argentina ediciones; 2004 (in Spanish)."},{"key":"e_1_3_3_4_2","volume-title":"The Spotted Maize Beetle","author":"Drinkwater TW.","year":"1998","unstructured":"Drinkwater TW. The Spotted Maize Beetle. Crop protection series number 6. ARC-Grain Crop Institute; 1998."},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1177\/10406387231215756"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1177\/03009858241309394"},{"key":"e_1_3_3_7_2","first-page":"1","article-title":"Cantharidin toxicosis to animal and human in the world: a review","volume":"1","author":"Ghoneim K.","year":"2013","unstructured":"Ghoneim K. Cantharidin toxicosis to animal and human in the world: a review. Standard Res J Toxicol Environ Health Sci. 2013;1:1\u201316.","journal-title":"Standard Res J Toxicol Environ Health Sci"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1177\/03009858241231557"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1093\/jee\/65.3.892"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-1910(03)00049-0"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.3390\/ani11010220"},{"issue":"4","key":"e_1_3_3_12_2","first-page":"377","article-title":"The toxicity of the pollen beetle Astylus atromaculatus blanch","volume":"43","author":"Kellerman TS","year":"1972","unstructured":"Kellerman TS, Adelaar TF, Minne JA. The toxicity of the pollen beetle Astylus atromaculatus blanch. J S Afr Vet Med Assoc. 1972;43(4):377\u2013381.","journal-title":"Vet Med Assoc"},{"key":"e_1_3_3_13_2","unstructured":"Kinney KK Peairs FB Swinker AM. Blister Beetles in Forage Crops. Colorado State University Extension; 2006. http:\/\/www.extension.colostate.edu\/docs\/pubs\/insect\/05524.pdf"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1177\/10406387241249180"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1080\/02571862.2007.10634807"},{"issue":"1","key":"e_1_3_3_16_2","first-page":"17","article-title":"Visitantes florales diurnos del girasol (Helianthus annuus, Asterales: Asteraceae) en la Argentina","volume":"69","author":"Torretta JP","year":"2010","unstructured":"Torretta JP, Medan D, roig Alsina A, et al. Visitantes florales diurnos del girasol (Helianthus annuus, Asterales: Asteraceae) en la Argentina. Rev Soc Entomol Argent. 2010;69(1\u20132):17\u201332.","journal-title":"Rev Soc Entomol Argent"},{"key":"e_1_3_3_17_2","unstructured":"V\u00e1zquez VA Costoya Puente JA del Mar Yllera Fern\u00e1ndez M et al. Reconocimiento y valoraci\u00f3n del dolor en animales de experimentaci\u00f3n [Recognition and Assessment of Pain in Laboratory Animals]. IBADER; 2020. Accessed June 12 2026. https:\/\/www.ibader.gal\/download.php?f=2020_MonogIBADER_VA-1369.pdf (in Spanish)."}],"container-title":["Veterinary Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/03009858261461767","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/03009858261461767","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/03009858261461767","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T07:01:31Z","timestamp":1793516491000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/03009858261461767"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,26]]},"references-count":16,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2026,11]]}},"alternative-id":["10.1177\/03009858261461767"],"URL":"https:\/\/doi.org\/10.1177\/03009858261461767","relation":{},"ISSN":["0300-9858","1544-2217"],"issn-type":[{"value":"0300-9858","type":"print"},{"value":"1544-2217","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,6,26]]}}}