{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T07:28:12Z","timestamp":1793518092048,"version":"4.5.0"},"reference-count":58,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T00:00:00Z","timestamp":1787616000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/501100010677","name":"Instituto Nacional de Tecnolog\u00eda Agropecuaria","doi-asserted-by":"publisher","award":["PD-I113, PD-I114, PD-I116 and RIST.I111"],"award-info":[{"award-number":["PD-I113, PD-I114, PD-I116 and RIST.I111"]}],"id":[{"id":"10.13039\/501100010677","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100020854","name":"asociaci\u00f3n cooperadora inta rafaela","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100020854","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Vet Pathol"],"published-print":{"date-parts":[[2026,11]]},"abstract":"<jats:p>\n                    Infectious abortion is a major cause of reproductive loss in cattle, yet the diagnosis remains challenging. In this study, we evaluated the gross and microscopic lesions of bovine fetuses aborted due to the main infectious agents in Argentina. Clear pathogen-specific patterns were identified.\n                    <jats:italic toggle=\"yes\">Neospora caninum<\/jats:italic>\n                    was strongly associated with central nervous system (CNS) and cardiac inflammation, whereas\n                    <jats:italic toggle=\"yes\">Campylobacter fetus<\/jats:italic>\n                    and\n                    <jats:italic toggle=\"yes\">Brucella abortus<\/jats:italic>\n                    predominantly produced bronchointerstitial pneumonia.\n                    <jats:italic toggle=\"yes\">Leptospira spp.<\/jats:italic>\n                    consistently affected hepatic and renal tissues and was associated with marked portal hepatitis and interstitial nephritis. Bovine viral diarrhea virus (BVDV) infections resulted in mild multisystemic and nonspecific lesions. Lesion severity also differed by fetal age.\n                    <jats:italic toggle=\"yes\">N. caninum<\/jats:italic>\n                    produced more severe CNS and cardiac inflammation in mid-gestation fetuses, and\n                    <jats:italic toggle=\"yes\">C. fetus<\/jats:italic>\n                    induced more severe hepatic lesions during mid-gestation. Statistical analyses confirmed distinct organ tropisms and lesion profiles among pathogens, supporting their diagnostic relevance. Based on these findings, targeted sampling of CNS and heart (for\n                    <jats:italic toggle=\"yes\">N. caninum<\/jats:italic>\n                    ); lung (for\n                    <jats:italic toggle=\"yes\">C. fetus<\/jats:italic>\n                    and\n                    <jats:italic toggle=\"yes\">B. abortus<\/jats:italic>\n                    ); liver and kidney (for\n                    <jats:italic toggle=\"yes\">Leptospira spp.<\/jats:italic>\n                    ); and heart, lung, and CNS (for BVDV) may improve diagnostic accuracy in abortion investigations. These findings provide robust criteria for differentiating major abortifacient agents in routine diagnostic practice.\n                  <\/jats:p>","DOI":"10.1177\/03009858261472502","type":"journal-article","created":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T07:05:38Z","timestamp":1787641538000},"page":"1097-1114","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Pathological characterization of the main infectious bovine abortions in Argentina"],"prefix":"10.1177","volume":"63","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2239-5966","authenticated-orcid":false,"given":"Emiliano","family":"Sosa","sequence":"first","affiliation":[{"name":"Estaci\u00f3n Experimental Agropecuaria, Balcarce, Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8047-6724","authenticated-orcid":false,"given":"Juan A.","family":"Garc\u00eda","sequence":"additional","affiliation":[{"name":"Estaci\u00f3n Experimental Agropecuaria, Balcarce, Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3978-5728","authenticated-orcid":false,"given":"Eleonora L.","family":"Morrell","sequence":"additional","affiliation":[{"name":"Estaci\u00f3n Experimental Agropecuaria, Balcarce, Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evangelina","family":"Miqueo","sequence":"additional","affiliation":[{"name":"Universidad Nacional de Mar del Plata, Balcarce, Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joaqu\u00edn","family":"Barale","sequence":"additional","affiliation":[{"name":"Estaci\u00f3n Experimental Agropecuaria, Balcarce, Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea E.","family":"Verna","sequence":"additional","affiliation":[{"name":"Estaci\u00f3n Experimental Agropecuaria, Balcarce, Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erika","family":"Gonz\u00e1lez Altamiranda","sequence":"additional","affiliation":[{"name":"Estaci\u00f3n Experimental Agropecuaria, Balcarce, Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda A.","family":"Fiorentino","sequence":"additional","affiliation":[{"name":"Estaci\u00f3n Experimental Agropecuaria, Balcarce, Argentina"},{"name":"Universidad Nacional de Mar del Plata, Balcarce, Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda V.","family":"Scioli","sequence":"additional","affiliation":[{"name":"Estaci\u00f3n Experimental Agropecuaria, Balcarce, Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dad\u00edn P.","family":"Moore","sequence":"additional","affiliation":[{"name":"Estaci\u00f3n Experimental Agropecuaria, Balcarce, Argentina"},{"name":"Universidad Nacional de Mar del Plata, Balcarce, Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luc\u00eda M.","family":"Campero","sequence":"additional","affiliation":[{"name":"Estaci\u00f3n Experimental Agropecuaria, Balcarce, Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda G.","family":"Cendoya","sequence":"additional","affiliation":[{"name":"Universidad Nacional de Mar del Plata, Balcarce, Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3494-8193","authenticated-orcid":false,"given":"Germ\u00e1n J.","family":"Cant\u00f3n","sequence":"additional","affiliation":[{"name":"Estaci\u00f3n Experimental Agropecuaria, Balcarce, Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,8,25]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.5829\/idosi.ejas.2016.347.355"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13028-015-0145-8"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetmic.2013.04.007"},{"key":"e_1_3_2_5_2","unstructured":"Alton GG Jones LM Angus RD et al. 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