{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T18:35:25Z","timestamp":1777919725810,"version":"3.51.4"},"reference-count":18,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[1969,1,1]],"date-time":"1969-01-01T00:00:00Z","timestamp":-31536000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pathologia veterinaria"],"published-print":{"date-parts":[[1969,1]]},"abstract":"<jats:p>\n                    Bacillary hemoglobinuria was expertmenially induced in rabbits by intravenous inoculation with Spores of\n                    <jats:italic>Clostridium bemolyticum<\/jats:italic>\n                    and subsequent hepatic biopsy. The biopsy wound disrupted the hepatic vasculature and damaged the adjacent parenchyma. This damage and the resulting hypoxia created conditions favorable for the germination of the inoculated spores. As the bacteria proliferated, their exotoxin lysed the hepatocytes and the erythrocytes in the immediate area. The bulk of the hepatic necrosis in bacillary hemoglobinuria was due to this exotoxin. Vascular thrombi caused by the exotoxic damage enhanced the development of the lesion.\n                  <\/jats:p>","DOI":"10.1177\/030098586900600105","type":"journal-article","created":{"date-parts":[[2010,3,8]],"date-time":"2010-03-08T17:27:48Z","timestamp":1268069268000},"page":"59-75","source":"Crossref","is-referenced-by-count":12,"title":["Experimental Bacillary Hemoglobinuria II. Pathogenesis of the Hepatic Lesion in the Rabbit"],"prefix":"10.1177","volume":"6","author":[{"given":"K. R.","family":"Van Kampen","sequence":"first","affiliation":[{"name":"Department of Pathology, School of Veterinary Medicine, University of California, Davis"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P. C.","family":"Kennedy","sequence":"additional","affiliation":[{"name":"Department of Pathology, School of Veterinary Medicine, University of California, Davis"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1969,1]]},"reference":[{"key":"e_1_2_1_2_1","first-page":"534","article-title":"Bovine bacillary hemoglobinuria","volume":"18","author":"Boyd A.G.","year":"1929","unstructured":"Boyd A.G.: Bovine bacillary hemoglobinuria. Monthly Bulletin of the Department of Agriculture, State of California 18: 534\u2013538 (1929).","journal-title":"Monthly Bulletin of the Department of Agriculture, State of California"},{"key":"e_1_2_1_3_1","first-page":"450","article-title":"Clostridial infection of the liver in the canine after ligation of the hepatic artery","volume":"5","author":"Cobb L.M.","year":"1962","unstructured":"Cobb L.M., McKay K.A., Archibald J., Markowitz J.: Clostridial infection of the liver in the canine after ligation of the hepatic artery. Canad. J. Surg. 5: 450\u2013460 (1962).","journal-title":"Canad. J. Surg."},{"key":"e_1_2_1_4_1","first-page":"1111","article-title":"A simplified instrument for obtaining liver biopsies in cattle","volume":"23","author":"Hughes J.P.","year":"1962","unstructured":"Hughes J.P.: A simplified instrument for obtaining liver biopsies in cattle. Amer. J. vet. Res. 23: 1111\u20131113 (1962).","journal-title":"Amer. J. vet. Res."},{"key":"e_1_2_1_5_1","unstructured":"Iverson J.P.: Eighth Biennial Report of the State Veterinarian of California pp. 8\u201310 (1916)."},{"key":"e_1_2_1_6_1","first-page":"143","article-title":"Studies of an obscure cattle disease in western Nevada","volume":"52","author":"Mack W.B.","year":"1917","unstructured":"Mack W.B., Records E.: Studies of an obscure cattle disease in western Nevada. J. amer. vet. med. Ass. 52: 143\u2013151 (1917).","journal-title":"J. amer. vet. med. Ass."},{"key":"e_1_2_1_7_1","first-page":"850","volume-title":"Experimental Surgery","author":"Markowitz J.","year":"1959","unstructured":"Markowitz J., Archibald J., Downie H.G.: Experimental Surgery, 4th Ed., p. 850 (Williams and Wilkins, Baltimore 1959).","edition":"4"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1128\/JB.53.2.139-147.1947"},{"key":"e_1_2_1_9_1","first-page":"552","article-title":"Studies to diagnose a fatal disease of cattle in the mountainous regions of California","volume":"48","author":"Meyer K.F.","year":"1916","unstructured":"Meyer K.F.: Studies to diagnose a fatal disease of cattle in the mountainous regions of California. J. amer. vet. med. Ass. 48: 552\u2013565 (1916).","journal-title":"J. amer. vet. med. Ass."},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1177\/030098586600300503"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1101\/SQB.1940.008.01.003"},{"key":"e_1_2_1_12_1","article-title":"Bacillary hemoglobinuria of cattle and sheep","volume":"173","author":"Records E.","year":"1945","unstructured":"Records E., Vawter L.R.: Bacillary hemoglobinuria of cattle and sheep. Ner. Agr. Exp. Bul. 173: (1945).","journal-title":"Ner. Agr. Exp. Bul."},{"key":"e_1_2_1_13_1","first-page":"494","article-title":"Recent studies of icterohemoglobinuria of cattle","volume":"68","author":"Records E.","year":"1926","unstructured":"Records E., Vawter L.R.: Recent studies of icterohemoglobinuria of cattle. J. amer. vet. med. Ass. 68: 494\u2013512 (1926).","journal-title":"J. amer. vet. med. Ass."},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.31.5.609"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.64.1.97"},{"key":"e_1_2_1_16_1","first-page":"649","volume-title":"Medical and Public Health Laboratory Methods","author":"Simmons J.S.","year":"1955","unstructured":"Simmons J.S., Gentzkow C.J.: Medical and Public Health Laboratory Methods, p. 649 (Lea and Febiger, Philadelphia 1955)."},{"key":"e_1_2_1_17_1","unstructured":"Turner A.W.: Black disease (infectious necrotic hepatitis) of sheep in Australia. Bul. 46 Coun. Sci. and Ind. Res. Commonwealth Australia (quoted by Records and Vawter 1945)."},{"key":"e_1_2_1_18_1","doi-asserted-by":"publisher","DOI":"10.1038\/icb.1943.9"},{"key":"e_1_2_1_19_1","first-page":"2173","article-title":"Experimental bacillary hemoglobinuria. I. Intrahepatic detection of spores of Clostridium hemolylicum by immunofluorescence in the rabbit","volume":"29","author":"Van Kampen K.R.","year":"1968","unstructured":"Van Kampen K.R., Kennedy P.C.: Experimental bacillary hemoglobinuria. I. Intrahepatic detection of spores of Clostridium hemolylicum by immunofluorescence in the rabbit. Amer. J. vet. Res. 29: 2173\u20132177 (1968).","journal-title":"Amer. J. vet. Res."}],"container-title":["Pathologia veterinaria"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/030098586900600105","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/030098586900600105","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T19:10:05Z","timestamp":1777662605000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/030098586900600105"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1969,1]]},"references-count":18,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1969,1]]}},"alternative-id":["10.1177\/030098586900600105"],"URL":"https:\/\/doi.org\/10.1177\/030098586900600105","relation":{},"ISSN":["0031-2975"],"issn-type":[{"value":"0031-2975","type":"print"}],"subject":[],"published":{"date-parts":[[1969,1]]}}}