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Electromyographic studies showed bizarre, high frequency discharges in all dogs. Examination of muscle biopsies taken from the biceps femoris muscle from each dog revealed mild degenerative changes of fiber size variation, focal necrosis and fiber splitting. Ragged red fibers were prominent and appeared to be related to mitochondrial aggregates. Significant (P &lt; 0.05) type 1 and 2 fiber atrophy was found in all dogs. Fiber grouping was present in four dogs. Studies of fascicular biopsies of the peroneal nerve showed thinly myelinated fibers, onion-bulb formation, segmental demyelination and short intercalated internodes. These findings suggested a glucocorticoid-related myopathy in hyperadrenocorticism that also may have a neurogenic component.<\/jats:p>","DOI":"10.1177\/030098588001700203","type":"journal-article","created":{"date-parts":[[2017,8,3]],"date-time":"2017-08-03T04:48:32Z","timestamp":1501735712000},"page":"134-148","source":"Crossref","is-referenced-by-count":30,"title":["Subclinical Myopathy Associated with Hyperadrenocorticism in the Dog"],"prefix":"10.1177","volume":"17","author":[{"given":"K. G.","family":"Braund","sequence":"first","affiliation":[{"name":"Scott-Ritchey Research Program, Department of Small Animal Surgery and Medicine, School of Veterinary Medicine, and Drug-related Analysis Research and Evaluation Program, School of Pharmacy, Auburn University, Auburn, Ala."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. 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