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The endothelial processes of the blood lakes had edematous swelling, vesiculation, and denudation. The microvilli of hepatocytes became swollen, blunted, and sloughed where the endothelial processes were disrupted. Subsequently, the hepatocytes were exposed directly to circulating blood cells and had degenerative changes with accumulation of red blood cells in the cytoplasm.<\/jats:p>\n                  <jats:p>The membrane-bound cysts were observed with the blood lakes and were bounded with atrophic hepatocytes or membranous wall extending to the Disse's space of adjacent hepatocytes. The cysts were filled with proteinaccous fluid, fibrin, and a few red blood cells. The wall of membrane-bound cysts consisted of endothelial processes extending from the endothelial cells of adjacent hepatocytes. The wall appeared to develop from adhesion of endothelial processes surrounding sinusoidal spaces of the hepatocytes following lysis of atrophic hepatocytes.<\/jats:p>","DOI":"10.1177\/030098588302000404","type":"journal-article","created":{"date-parts":[[2010,1,27]],"date-time":"2010-01-27T01:47:57Z","timestamp":1264556877000},"page":"410-423","source":"Crossref","is-referenced-by-count":16,"title":["Peliosis Hepatis-like Lesion in Aging Rats"],"prefix":"10.1177","volume":"20","author":[{"given":"K. P.","family":"Lee","sequence":"first","affiliation":[{"name":"Haskell Laboratory for Toxicology and Industrial Medicine. E. I. du Pont de Nemours and Company. 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