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The marked heterogeneity in lysozyme expression in cutaneous histiocytoma may indicate that a proportion of these tumors show relatively primitive histiocytic differentiation and do not express lysozyme. Alternatively, this same proportion may exhibit a phenotype akin to cutaneous Langerhans cells which do not contain lysozyme. Lysozyme was not detectable in the tumor cells in lymphomatoid granulomatosis, atypical cutaneous histiocytoma, and histiocytic lymphosarcoma. Other evidence that these three disorders do not represent true histiocytic proliferative disorders is discussed.<\/jats:p>","DOI":"10.1177\/030098588602300615","type":"journal-article","created":{"date-parts":[[2017,1,16]],"date-time":"2017-01-16T23:49:11Z","timestamp":1484610551000},"page":"757-762","source":"Crossref","is-referenced-by-count":51,"title":["Utilization of Cytoplasmic Lysozyme Immunoreactivity as a Histiocytic Marker in Canine Histiocytic Disorders"],"prefix":"10.1177","volume":"23","author":[{"given":"P. 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