{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T18:45:01Z","timestamp":1777920301442,"version":"3.51.4"},"reference-count":19,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[1987,1,1]],"date-time":"1987-01-01T00:00:00Z","timestamp":536457600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vet Pathol"],"published-print":{"date-parts":[[1987,1]]},"abstract":"<jats:p>A distinctive periadnexal multinodular granulomatous dermatitis of unknown cause was diagnosed over a 6-year period in 22 dogs (13 males and nine females) aged 8 months to 10 years, purebred as well as mixed-breed. Nodules, usually more than two, started on the face and were often unaccompanied by signs of irritation. All dogs were otherwise healthy except a Viszla with bilateral anterior uveitis and a Basset hound with nasal congestion and sneezing. Microscopically, cutaneous lesions occurred in a periadnexal pattern, replaced sebaceous glands, coalesced, and extended into the subcutis and in more advanced cases through the panniculus carnosus. Infectious agents were not demonstrated by aerobic, anaerobic, or fungus cultures or by light or electron microscopy, nor were ectoparasites seen. Immunofluorescence and peroxidase-antiperoxidase techniques gave negative results for intraepidermal and basement membrane deposits of IgA, IgG, IgM, and C3. Lesions were unresponsive to a variety of antibiotics; they regressed spontaneously in two untreated dogs and rapidly in dogs given only corticosteroid therapy. Continuous low-dose corticosteroids were necessary in a few dogs to prevent recurrence.<\/jats:p>","DOI":"10.1177\/030098588702400102","type":"journal-article","created":{"date-parts":[[2017,1,13]],"date-time":"2017-01-13T15:00:03Z","timestamp":1484319603000},"page":"5-10","source":"Crossref","is-referenced-by-count":19,"title":["Idiopathic Periadnexal Multinodular Granulomatous Dermatitis in Twenty-two Dogs"],"prefix":"10.1177","volume":"24","author":[{"given":"J. L.","family":"Carpenter","sequence":"first","affiliation":[{"name":"Departments of Pathology and Medicine, Angell Memorial Animal Hospital, Boston, MA"},{"name":"New England Regional Primate Research Center, Southboro, MA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G. W.","family":"Thornton","sequence":"additional","affiliation":[{"name":"Departments of Pathology and Medicine, Angell Memorial Animal Hospital, Boston, MA"},{"name":"New England Regional Primate Research Center, Southboro, MA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F. M.","family":"Moore","sequence":"additional","affiliation":[{"name":"Departments of Pathology and Medicine, Angell Memorial Animal Hospital, Boston, MA"},{"name":"New England Regional Primate Research Center, Southboro, MA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"Jr.","given":"N. W.","family":"King","sequence":"additional","affiliation":[{"name":"Departments of Pathology and Medicine, Angell Memorial Animal Hospital, Boston, MA"},{"name":"New England Regional Primate Research Center, Southboro, MA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1987,1]]},"reference":[{"key":"e_1_2_1_2_1","first-page":"385","volume-title":"Histologic Diagnosis of Inflammatory Skin Disease","author":"Ackerman AB","year":"1978","unstructured":"Ackerman AB: Histologic Diagnosis of Inflammatory Skin Disease, p. 385. Lea & Febiger, Philadelphia, 1978"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.1986.188.04.377"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000372-198312000-00013"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.1982.181.11.1432"},{"key":"e_1_2_1_6_1","first-page":"7","volume-title":"Diagnostic Immunohistochemistry","author":"DeLellis RA","year":"1981","unstructured":"DeLellis RA: Diagnostic Immunohistochemistry, p. 7. Masson Publishing, New York, 1981"},{"key":"e_1_2_1_7_1","first-page":"103","article-title":"Granulomatous dermatitis in carnivores associated with dermatophyte infection.","volume":"21","author":"Holfeld NW","year":"1980","unstructured":"Holfeld NW, Schiefer B, Boycott BR: Granulomatous dermatitis in carnivores associated with dermatophyte infection. Canadian Vet J 21: 103, 1980","journal-title":"Canadian Vet J"},{"key":"e_1_2_1_8_1","first-page":"321","article-title":"Cutaneous histiocytomas of dogs.","volume":"32","author":"Howard EB","year":"1969","unstructured":"Howard EB, Nielsen SW: Cutaneous histiocytomas of dogs. Nat Cancer Inst Monogr 32: 321, 1969","journal-title":"Nat Cancer Inst Monogr"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.1982.181.08.794"},{"key":"e_1_2_1_10_1","doi-asserted-by":"crossref","unstructured":"Moore FM White SD Carpenter JL Torchon E: Localization of immunoglobulins and complement by the peroxidase-antiperoxidase method in autoimmune and non-autoimmune canine dermatopathies. 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J Am Anim Hosp Assoc 16: 595, 1980","journal-title":"J Am Anim Hosp Assoc"},{"key":"e_1_2_1_14_1","first-page":"233","article-title":"Nodular skin disease associated with Dirofilaria immitis infection in a dog.","volume":"69","author":"Scott DW","year":"1979","unstructured":"Scott DW: Nodular skin disease associated with Dirofilaria immitis infection in a dog. Cornell Vet 69: 233, 1979","journal-title":"Cornell Vet"},{"key":"e_1_2_1_15_1","first-page":"467","volume-title":"Current Veterinary Therapy VII","author":"Scott DW","year":"1980","unstructured":"Scott DW: Canine pododermatitis. In: Current Veterinary Therapy VII, ed. Kirk RW, p. 467. WB Saunders CO, Philadelphia, 1980"},{"key":"e_1_2_1_16_1","first-page":"529","article-title":"Cutaneous eosinophilic granuloma with collagen degeneration in the dog.","volume":"19","author":"Turnwald GH","year":"1983","unstructured":"Turnwald GH, Hoskins JD, Taylor HW: Cutaneous eosinophilic granuloma with collagen degeneration in the dog. 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