{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T02:06:33Z","timestamp":1787018793546,"version":"build-2736575974"},"reference-count":18,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[1987,5,1]],"date-time":"1987-05-01T00:00:00Z","timestamp":546825600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vet Pathol"],"published-print":{"date-parts":[[1987,5]]},"abstract":"<jats:p>Interstitial cell tumors from nine stallions were described. In all but one horse the tumors were found in undescended testes. Five animals had bilateral tumors. Two animals showed increased aggression. Tumors contained two cell types. The first type were large distinctly bordered eosinophilic cells interpreted to be hyperplastic and hypertrophic interstitial cells. They blended with pleomorphic often spindloid neoplastic cells which had fibrillar, vacuolated cytoplasm and indistinct cell borders. This latter cell population was arranged in nodules or broad sheets as endocrine-like packets or interweaving fascicles. Biologic behavior of the neoplasms could not be ascertained from histologic examination.<\/jats:p>","DOI":"10.1177\/030098588702400306","type":"journal-article","created":{"date-parts":[[2017,1,15]],"date-time":"2017-01-15T17:43:20Z","timestamp":1484502200000},"page":"231-234","source":"Crossref","is-referenced-by-count":31,"title":["Equine Testicular Interstitial Cell Tumors"],"prefix":"10.1177","volume":"24","author":[{"given":"H. B.","family":"Gelberg","sequence":"first","affiliation":[{"name":"Department of Veterinary Pathobiology, College of Veterinary Medicine, University of Illinois, Urbana, IL"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"McEntee","sequence":"additional","affiliation":[{"name":"Department of Veterinary Pathobiology, College of Veterinary Medicine, University of Illinois, Urbana, IL"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[1987,5]]},"reference":[{"key":"e_1_2_1_2_1","first-page":"533","article-title":"Cancer du testicule droit, chez un mulet (tumeur des cellules interstitielles).","volume":"78","author":"Ball V","year":"1926","unstructured":"Ball V, Douville M: Cancer du testicule droit, chez un mulet (tumeur des cellules interstitielles). Rev M\u00e9d V\u00e9t (Toulouse) 78: 533\u2013536, 1926","journal-title":"Rev M\u00e9d V\u00e9t (Toulouse)"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0368-1742(60)80024-0"},{"key":"e_1_2_1_4_1","first-page":"348","article-title":"Heterogeneity of induced testicular interstitial cell tumors of mice as evidenced by steroid biosynthetic enzyme activities.","volume":"28","author":"Dominguez DV","year":"1968","unstructured":"Dominguez DV, Huseby RA: Heterogeneity of induced testicular interstitial cell tumors of mice as evidenced by steroid biosynthetic enzyme activities. Cancer Res 28: 348\u2013353, 1968","journal-title":"Cancer Res"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1210\/endo-105-5-1135"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00419291"},{"key":"e_1_2_1_7_1","first-page":"177","article-title":"Estrogen-induced Leydig cell tumor in the mouse: a model system for the study of carcinogenesis and hormone dependency.","volume":"1","author":"Huseby RA","year":"1976","unstructured":"Huseby RA: Estrogen-induced Leydig cell tumor in the mouse: a model system for the study of carcinogenesis and hormone dependency. J Toxicol Environ Health (Suppl) 1: 177\u2013192, 1976","journal-title":"J Toxicol Environ Health (Suppl)"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.1973.163.12.1364"},{"key":"e_1_2_1_9_1","first-page":"15","volume-title":"Tumors of Domestic Animals","author":"Moulton JE","year":"1978","unstructured":"Moulton JE: Tumors of the genital system. In: Tumors of Domestic Animals, ed. Moulton JE, 2nd ed., pp. 15\u2013317. SAGE Publications, Berkeley, 1978","edition":"2"},{"key":"e_1_2_1_10_1","first-page":"561","article-title":"Malignant interstitial cell tumor of the testis: a problem in endocrine oncology.","volume":"52","author":"Ober WB","year":"1976","unstructured":"Ober WB, Kabakow B, Hecht H: Malignant interstitial cell tumor of the testis: a problem in endocrine oncology. Bull NY Acad Med 52: 561\u2013583, 1976","journal-title":"Bull NY Acad Med"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01887267"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0737-0806(84)80101-X"},{"key":"e_1_2_1_13_1","first-page":"461","article-title":"Sur le mode de d\u00e9veloppement des tumeurs de la gland interstitielle du testicule chez le cheval.","volume":"84","author":"Peyron A","year":"1921","unstructured":"Peyron A: Sur le mode de d\u00e9veloppement des tumeurs de la gland interstitielle du testicule chez le cheval. CR Soc Biol (Paris) 84: 461\u2013464, 1921","journal-title":"CR Soc Biol (Paris)"},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod24.3.534"},{"key":"e_1_2_1_15_1","first-page":"10","volume-title":"The Mammalian Testis","author":"Setchell BP","year":"1978","unstructured":"Setchell BP: The Mammalian Testis, p. 10. Cornell University Press, Ithaca, NY, 1978"},{"key":"e_1_2_1_16_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcp\/67.6.562"},{"key":"e_1_2_1_17_1","first-page":"356","article-title":"Interstitial cell tumor of the equine testis.","volume":"124","author":"Smith HA","year":"1954","unstructured":"Smith HA: Interstitial cell tumor of the equine testis. J Am Vet Med Assoc 124: 356\u2013359, 1954","journal-title":"J Am Vet Med Assoc"},{"key":"e_1_2_1_18_1","first-page":"284","article-title":"Leydig cell tumor induced hypercalcemia in the Fischer rat.","volume":"108","author":"Troyer H","year":"1982","unstructured":"Troyer H, Sowers JR, Babich E: Leydig cell tumor induced hypercalcemia in the Fischer rat. Am J Pathol 108: 284\u2013290, 1982","journal-title":"Am J Pathol"},{"key":"e_1_2_1_19_1","first-page":"307","article-title":"Interstitial cell growths of the testicle.","volume":"19","author":"Warren S","year":"1943","unstructured":"Warren S, Olshausen KW: Interstitial cell growths of the testicle. Am J Pathol 19: 307\u2013331, 1943","journal-title":"Am J Pathol"}],"container-title":["Veterinary Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/030098588702400306","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/030098588702400306","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T19:26:44Z","timestamp":1777663604000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/030098588702400306"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1987,5]]},"references-count":18,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1987,5]]}},"alternative-id":["10.1177\/030098588702400306"],"URL":"https:\/\/doi.org\/10.1177\/030098588702400306","relation":{},"ISSN":["0300-9858","1544-2217"],"issn-type":[{"value":"0300-9858","type":"print"},{"value":"1544-2217","type":"electronic"}],"subject":[],"published":{"date-parts":[[1987,5]]}}}