{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T18:45:15Z","timestamp":1777920315054,"version":"3.51.4"},"reference-count":32,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[1987,7,1]],"date-time":"1987-07-01T00:00:00Z","timestamp":552096000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vet Pathol"],"published-print":{"date-parts":[[1987,7]]},"abstract":"<jats:p>\n                    <jats:italic toggle=\"yes\">Moraxella bovis<\/jats:italic>\n                    was instilled into the conjunctival sac of gnotobiotic calves and corneas were sampled serially after infection. Lesions developed in seven of eight infected calves, but were absent in a noninfected control calf. Histologically,\n                    <jats:italic toggle=\"yes\">M. bovis<\/jats:italic>\n                    was first seen in foci of swollen epithelium and within basal epithelial cells adjacent to ulcers. Corneal ulcers were severe in later stages of infection; fibrin deposits, neutrophils, and bacteria were present in the stromas. Examination of early lesions by scanning electron microscopy showed\n                    <jats:italic toggle=\"yes\">M. bovis<\/jats:italic>\n                    in pits on the surfaces of dark epithelial cells, enmeshed in degenerate epithelial cells and within erosions and an ulcer; in later samples, bacteria were rare. Ultrastructurally,\n                    <jats:italic toggle=\"yes\">M. bovis<\/jats:italic>\n                    was seen in surface pits in superficial epithelial cell processes and within swollen epithelial cells. In stroma,\n                    <jats:italic toggle=\"yes\">M. bovis<\/jats:italic>\n                    was frequently seen among collagen fibrils, within neutrophil phagosomes, and associated with cellular debris. This study demonstrates that a virulent strain of\n                    <jats:italic toggle=\"yes\">M. bovis<\/jats:italic>\n                    can invade bovine corneal epithelial cells and can cause keratitis in the absence of injurious ultraviolet irradiation or other known predisposing environmental factors.\n                  <\/jats:p>","DOI":"10.1177\/030098588702400401","type":"journal-article","created":{"date-parts":[[2017,1,15]],"date-time":"2017-01-15T12:36:14Z","timestamp":1484483774000},"page":"287-295","source":"Crossref","is-referenced-by-count":44,"title":["Pathogenesis of Corneal Lesions Caused by\n                    <i>Moraxella bovis<\/i>\n                    in Gnotobiotic Calves"],"prefix":"10.1177","volume":"24","author":[{"given":"D. G.","family":"Rogers","sequence":"first","affiliation":[{"name":"National Animal Disease Center, Agricultural Research Service, United States Department of Agriculture, Ames, IA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N. F.","family":"Cheville","sequence":"additional","affiliation":[{"name":"National Animal Disease Center, Agricultural Research Service, United States Department of Agriculture, Ames, IA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"Jr.","given":"G. W.","family":"Pugh","sequence":"additional","affiliation":[{"name":"National Animal Disease Center, Agricultural Research Service, United States Department of Agriculture, Ames, IA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1987,7]]},"reference":[{"key":"e_1_2_2_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0034-5288(18)31752-1"},{"key":"e_1_2_2_3_1","first-page":"180","article-title":"A study of bovine infectious keratitis.","volume":"6","author":"Baldwin EM","year":"1945","unstructured":"Baldwin EMJr: A study of bovine infectious keratitis. 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