{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T18:45:26Z","timestamp":1777920326349,"version":"3.51.4"},"reference-count":22,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[1987,9,1]],"date-time":"1987-09-01T00:00:00Z","timestamp":557452800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vet Pathol"],"published-print":{"date-parts":[[1987,9]]},"abstract":"<jats:p>\n                    A 7-month-old Balinese cat with progressive neurological dysfunction had histopathological lesions of brain, liver, kidney, spleen, and lung consistent with a lysosomal storage disease. Ultrastructural examination revealed lysosomal hypertrophy with membranous inclusions. Hepatic sphingomyelin and cholesterol were elevated 10 times normal, and total phospholipids were increased 3.6 fold. Sphingomyelinase activity measured with\n                    <jats:sup>14<\/jats:sup>\n                    C labeled sphingomyelin at pH 5.0 was virtually absent in brain and liver. Other lysosomal hydrolase activities were normal or elevated. Clinical, morphological, and biochemical findings suggest that this cat had sphingomyelin lipidosis similar to human Niemann-Pick disease type A, and that feline sphingomyelin lipidosis provides another model of human lysosomal storage disease.\n                  <\/jats:p>","DOI":"10.1177\/030098588702400504","type":"journal-article","created":{"date-parts":[[2017,1,13]],"date-time":"2017-01-13T17:40:24Z","timestamp":1484329224000},"page":"386-391","source":"Crossref","is-referenced-by-count":25,"title":["Sphingomyelin Lipidosis in a Cat"],"prefix":"10.1177","volume":"24","author":[{"given":"H. J.","family":"Baker","sequence":"first","affiliation":[{"name":"Department of Comparative Medicine, Bowman Gray School of Medicine, Winston-Salem, NC"},{"name":"Department of Pediatrics, University of Colorado Health Science Center, Denver, CO"},{"name":"Department of Neuroscience, Albert Einstein College of Medicine, Bronx, NY"},{"name":"Division of Human Genetics, Children's Hospital of Buffalo, Buffalo, NY"},{"name":"Abrams Veterinary Hospital, Dallas, TX"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P. A.","family":"Wood","sequence":"additional","affiliation":[{"name":"Department of Comparative Medicine, Bowman Gray School of Medicine, Winston-Salem, NC"},{"name":"Department of Pediatrics, University of Colorado Health Science Center, Denver, CO"},{"name":"Department of Neuroscience, Albert Einstein College of Medicine, Bronx, NY"},{"name":"Division of Human Genetics, Children's Hospital of Buffalo, Buffalo, NY"},{"name":"Abrams Veterinary Hospital, Dallas, TX"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D. A.","family":"Wenger","sequence":"additional","affiliation":[{"name":"Department of Comparative Medicine, Bowman Gray School of Medicine, Winston-Salem, NC"},{"name":"Department of Pediatrics, University of Colorado Health Science Center, Denver, CO"},{"name":"Department of Neuroscience, Albert Einstein College of Medicine, Bronx, NY"},{"name":"Division of Human Genetics, Children's Hospital of Buffalo, Buffalo, NY"},{"name":"Abrams Veterinary Hospital, Dallas, TX"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S. U.","family":"Walkley","sequence":"additional","affiliation":[{"name":"Department of Comparative Medicine, Bowman Gray School of Medicine, Winston-Salem, NC"},{"name":"Department of Pediatrics, University of Colorado Health Science Center, Denver, CO"},{"name":"Department of Neuroscience, Albert Einstein College of Medicine, Bronx, NY"},{"name":"Division of Human Genetics, Children's Hospital of Buffalo, Buffalo, NY"},{"name":"Abrams Veterinary Hospital, Dallas, TX"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Inui","sequence":"additional","affiliation":[{"name":"Department of Comparative Medicine, Bowman Gray School of Medicine, Winston-Salem, NC"},{"name":"Department of Pediatrics, University of Colorado Health Science Center, Denver, CO"},{"name":"Department of Neuroscience, Albert Einstein College of Medicine, Bronx, NY"},{"name":"Division of Human Genetics, Children's Hospital of Buffalo, Buffalo, NY"},{"name":"Abrams Veterinary Hospital, Dallas, TX"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"Kudoh","sequence":"additional","affiliation":[{"name":"Department of Comparative Medicine, Bowman Gray School of Medicine, Winston-Salem, NC"},{"name":"Department of Pediatrics, University of Colorado Health Science Center, Denver, CO"},{"name":"Department of Neuroscience, Albert Einstein College of Medicine, Bronx, NY"},{"name":"Division of Human Genetics, Children's Hospital of Buffalo, Buffalo, NY"},{"name":"Abrams Veterinary Hospital, Dallas, TX"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. C.","family":"Rattazzi","sequence":"additional","affiliation":[{"name":"Department of Comparative Medicine, Bowman Gray School of Medicine, Winston-Salem, NC"},{"name":"Department of Pediatrics, University of Colorado Health Science Center, Denver, CO"},{"name":"Department of Neuroscience, Albert Einstein College of Medicine, Bronx, NY"},{"name":"Division of Human Genetics, Children's Hospital of Buffalo, Buffalo, NY"},{"name":"Abrams Veterinary Hospital, Dallas, TX"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B. L.","family":"Riddle","sequence":"additional","affiliation":[{"name":"Department of Comparative Medicine, Bowman Gray School of Medicine, Winston-Salem, NC"},{"name":"Department of Pediatrics, University of Colorado Health Science Center, Denver, CO"},{"name":"Department of Neuroscience, Albert Einstein College of Medicine, Bronx, NY"},{"name":"Division of Human Genetics, Children's Hospital of Buffalo, Buffalo, NY"},{"name":"Abrams Veterinary Hospital, Dallas, TX"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1987,9]]},"reference":[{"key":"e_1_2_2_2_1","first-page":"229","article-title":"Animal model: mouse Niemann-Pick's disease.","volume":"85","author":"Adachi M","year":"1976","unstructured":"Adachi M, Volk BW, Schneck L: Animal model: mouse Niemann-Pick's disease. 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McGraw-Hill, New York, 1983","edition":"5"},{"key":"e_1_2_2_7_1","doi-asserted-by":"publisher","DOI":"10.1177\/030098587901600504"},{"key":"e_1_2_2_8_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.1970.156.05.616"},{"key":"e_1_2_2_9_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197509252931304"},{"key":"e_1_2_2_10_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.1979.175.05.457"},{"key":"e_1_2_2_11_1","first-page":"229","article-title":"A lysosomal storage disorder in mice: a model of Niemann-Pick disease.","volume":"5","author":"Sakiyama T","year":"1976","unstructured":"Sakiyama T, Tsuda M, Kitagawa T: A lysosomal storage disorder in mice: a model of Niemann-Pick disease. J Inher Metabol Dis 5: 229, 1976","journal-title":"J Inher Metabol Dis"},{"key":"e_1_2_2_12_1","first-page":"136","article-title":"Feline lipidosis.","volume":"92","author":"Percy DH","year":"1971","unstructured":"Percy DH, Jortner BS: Feline lipidosis. 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