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Cardiomegaly with marked atrial and ventricular myocardial mineralization was seen at necropsy. Histologically. the random, myopathic foci were characterized by severe myocardial degeneration, mineralization, and fibrosis. Mural thrombosis, pulmonary arteriosclerosis, and mild myocardial inflammatory cell infiltrates were also present. Pathological changes were similar to those of dystrophic cardiac calcinosis, an incidental necropsy finding in certain mouse strains.<\/jats:p>","DOI":"10.1177\/030098588802500202","type":"journal-article","created":{"date-parts":[[2010,1,26]],"date-time":"2010-01-26T18:17:42Z","timestamp":1264529862000},"page":"113-118","source":"Crossref","is-referenced-by-count":23,"title":["High Mortality with Severe Dystrophic Cardiac Calcinosis in C3H\/OUJ Mice Fed High Fat Purified Diets"],"prefix":"10.1177","volume":"25","author":[{"given":"J. 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