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Megakaryocytes were dysmorphic and had evidence of abnormal maturation, with large numbers of megakaryoblasts containing alpha granules and poorly organized and reduplicated demarcation membranes. The fewer, more mature megakaryocytes lacked normal cytoplasmic organization. Most notable was the absence of well-demarcated \u201cplatelet fields,\u201d due to the excessive and disorderly array of demarcation membranes.<\/jats:p>","DOI":"10.1177\/030098588902600401","type":"journal-article","created":{"date-parts":[[2010,1,26]],"date-time":"2010-01-26T10:47:53Z","timestamp":1264502873000},"page":"289-293","source":"Crossref","is-referenced-by-count":8,"title":["Ultrastructural Analysis of Platelets and Megakaryocytes from a Dog with Probable Essential Thrombocythemia"],"prefix":"10.1177","volume":"26","author":[{"given":"F.","family":"Tablin","sequence":"first","affiliation":[{"name":"Department of Anatomy, Department of Clinical Pathology, and Department of Medicine, School of Veterinary Medicine, University of California-Davis, Davis, CA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N. 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