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In cats with mannosidosis, light microscopic examination revealed vacuoles in lymphocytes and monocytes, whereas electron microscopic studies demonstrated additional vacuoles in neutrophils, eosinophils, and basophils. In cats with mucopolysaccharidosis VI (MPS VI), vacuoles containing metachromatic granules were observed in lymphocytes, neutrophils, eosinophils, and monocytes. Ultrastructural studies of these cells identified the accumulation of fibrillar material, which often was associated with lamellated membrane structures.<\/jats:p>","DOI":"10.1177\/030098588902600402","type":"journal-article","created":{"date-parts":[[2010,1,26]],"date-time":"2010-01-26T10:47:53Z","timestamp":1264502873000},"page":"294-302","source":"Crossref","is-referenced-by-count":14,"title":["Morphology of Leukocytes from Cats Affected with \u03b1-Mannosidosis and Mucopolysaccharidosis VI (MPS VI)"],"prefix":"10.1177","volume":"26","author":[{"given":"J.","family":"Alroy","sequence":"first","affiliation":[{"name":"Department of Pathology, Tufts University Schools of Medicine and Veterinary Medicine, Boston and Grafton, MA; Department of Biochemistry, E. K. Shriver Center for Mental Retardation Inc., Waltham, MA; and Department of Medicine, Tufts University School of Veterinary Medicine, Grafton, MA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G. 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