{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T11:47:45Z","timestamp":1777463265275,"version":"3.51.4"},"reference-count":46,"publisher":"SAGE Publications","issue":"11","license":[{"start":{"date-parts":[[2023,7,14]],"date-time":"2023-07-14T00:00:00Z","timestamp":1689292800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/501100020884","name":"nacional de investigaci\u00f3n y desarrol","doi-asserted-by":"publisher","award":["Fonis SA19I0138"],"award-info":[{"award-number":["Fonis SA19I0138"]}],"id":[{"id":"10.13039\/501100020884","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["British Journal of Occupational Therapy"],"published-print":{"date-parts":[[2023,11]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Experts suggest implementing measures that include analgesia, sedation, delirium prevention and early mobilization (ASDM) in patients undergoing mechanical ventilation (MV) to reduce complications. However, there is limited evidence of occupational therapy in these patients. The aim of the research is to compare functional independence in patients undergoing MV of an intensive and early occupational therapy protocol versus to standard ASDM strategy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method\/Design:<\/jats:title>\n                    <jats:p>A prospective, multicenter, randomized clinical trial, with parallel groups (control and intervention groups). Participants will be hospitalized patients, over 18\u2009years of age, admitted to the intensive care unit (ICU) and with the need of invasive MV. The intervention group will receive two daily 30-minute sessions of occupational therapy for 10\u2009days. This study will research the effect of occupational therapy on functional independence, motor and cognitive status, evaluating at days 28 and 90.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion:<\/jats:title>\n                    <jats:p>This work contributes to the theoretical and practical work of occupational therapists who work in the ICU. The implementation of protocols of occupational therapy in mechanically ventilated patients can contribute to the independence and functionality of patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Our research aims to contribute to the generation of systematized, organized, and feasible protocols that can be implemented in ICU.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Trial Registration:<\/jats:title>\n                    <jats:p>ClinicalTrials.gov NCT04819529<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/03080226231184992","type":"journal-article","created":{"date-parts":[[2023,7,14]],"date-time":"2023-07-14T07:44:08Z","timestamp":1689320648000},"page":"728-739","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Early occupational therapy in mechanically ventilated patients improves functional status: Study protocol"],"prefix":"10.1177","volume":"86","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7701-4759","authenticated-orcid":false,"given":"Evelyn","family":"\u00c1lvarez","sequence":"first","affiliation":[{"name":"Departamento de Terapia Ocupacional y Ciencia de la Ocupaci\u00f3n, Facultad de Medicina, Universidad de Chile, Santiago, Chile"},{"name":"Centro de Estudios en Neurociencia Humana y Neuropsicolog\u00eda, Facultad de Psicolog\u00eda, Universidad Diego Portales, Santiago, Chile"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9118-2388","authenticated-orcid":false,"given":"Maricel","family":"Garrido","sequence":"additional","affiliation":[{"name":"Servicio de Medicina F\u00edsica y Rehabilitaci\u00f3n, Departamento de Medicina, Hospital Cl\u00ednico de la Universidad de Chile, Santiago, Chile"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Felipe","family":"Salech","sequence":"additional","affiliation":[{"name":"Centro de Investigaci\u00f3n Cl\u00ednica Avanzada (CICA), Hospital Cl\u00ednico de la Universidad de Chile, Santiago, Chile"},{"name":"Secci\u00f3n de Geriatr\u00eda, Hospital Cl\u00ednico de la Universidad de Chile, Santiago, Chile"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ver\u00f3nica","family":"Rojas","sequence":"additional","affiliation":[{"name":"Centro de Investigaci\u00f3n Cl\u00ednica Avanzada (CICA), Hospital Cl\u00ednico de la Universidad de Chile, Santiago, Chile"},{"name":"Unidad de Pacientes Cr\u00edticos, Departamento de Medicina, Hospital Cl\u00ednico de la Universidad de Chile, Santiago, Chile"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicole","family":"Jara","sequence":"additional","affiliation":[{"name":"Servicio de Medicina F\u00edsica y Rehabilitaci\u00f3n, Departamento de Medicina, Hospital Cl\u00ednico de la Universidad de Chile, Santiago, Chile"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9 I.","family":"Far\u00edas","sequence":"additional","affiliation":[{"name":"Centro de Investigaci\u00f3n Cl\u00ednica Avanzada (CICA), Hospital Cl\u00ednico de la Universidad de Chile, Santiago, Chile"},{"name":"Unidad de Pacientes Cr\u00edticos, Departamento de Medicina, Hospital Cl\u00ednico de la Universidad de Chile, Santiago, Chile"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniela","family":"Ponce","sequence":"additional","affiliation":[{"name":"Centro de Investigaci\u00f3n Cl\u00ednica Avanzada (CICA), Hospital Cl\u00ednico de la Universidad de Chile, Santiago, Chile"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eduardo","family":"Tobar","sequence":"additional","affiliation":[{"name":"Unidad de Pacientes Cr\u00edticos, Departamento de Medicina, Hospital Cl\u00ednico de la Universidad de Chile, Santiago, Chile"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2023,7,14]]},"reference":[{"key":"bibr1-03080226231184992","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrc.2016.09.002"},{"key":"bibr2-03080226231184992","doi-asserted-by":"publisher","DOI":"10.1590\/0004-282X20160018"},{"key":"bibr3-03080226231184992","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrc.2012.03.001"},{"key":"bibr4-03080226231184992","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0000000000002149"},{"key":"bibr5-03080226231184992","doi-asserted-by":"publisher","DOI":"10.7326\/M17-0046"},{"key":"bibr6-03080226231184992","doi-asserted-by":"publisher","DOI":"10.1503\/cmaj.071056"},{"key":"bibr7-03080226231184992","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0000000000003999"},{"key":"bibr8-03080226231184992","doi-asserted-by":"publisher","DOI":"10.5935\/0103-507X.20190066"},{"key":"bibr9-03080226231184992","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0b013e3181fd66e5"},{"key":"bibr10-03080226231184992","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0000000000003299"},{"key":"bibr11-03080226231184992","first-page":"161","volume":"24","author":"Duprey MS","year":"2020","journal-title":"Critical Care\/the Society of Critical Care Medicine"},{"key":"bibr12-03080226231184992","volume":"6","author":"Fletcher-Smith JC","year":"2013","journal-title":"Cochrane Database of Systematic Reviews"},{"key":"bibr13-03080226231184992","doi-asserted-by":"publisher","DOI":"10.4067\/S0034-98872013000100012"},{"key":"bibr14-03080226231184992","doi-asserted-by":"publisher","DOI":"10.1097\/01.CCM.0000227174.30337.3E"},{"key":"bibr15-03080226231184992","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201512-2343OC"},{"key":"bibr16-03080226231184992","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.g1687"},{"key":"bibr17-03080226231184992","doi-asserted-by":"publisher","DOI":"10.1111\/wvn.12462"},{"key":"bibr18-03080226231184992","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199903043400901"},{"key":"bibr19-03080226231184992","doi-asserted-by":"publisher","DOI":"10.1016\/j.suc.2017.07.007"},{"key":"bibr20-03080226231184992","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2014.2637"},{"key":"bibr21-03080226231184992","doi-asserted-by":"publisher","DOI":"10.1097\/RNJ.0000000000000226"},{"key":"bibr22-03080226231184992","volume":"7","author":"Legg LA","year":"2017","journal-title":"Cochrane Database of Systematic Reviews"},{"key":"bibr23-03080226231184992","doi-asserted-by":"publisher","DOI":"10.1097\/CCE.0000000000000567"},{"key":"bibr24-03080226231184992","doi-asserted-by":"publisher","DOI":"10.1016\/j.apmr.2012.10.023"},{"key":"bibr25-03080226231184992","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccc.2016.12.005"},{"key":"bibr26-03080226231184992","doi-asserted-by":"publisher","DOI":"10.1093\/ageing\/afs060"},{"key":"bibr27-03080226231184992","doi-asserted-by":"publisher","DOI":"10.1186\/s13054-020-03446-9"},{"key":"bibr28-03080226231184992","unstructured":"MINSAL (2013) Problema de Salud AUGE N\u00b037 Accidente Cerebrovascular Isqu\u00e9mico En Personas de 15 A\u00f1os Y M\u00e1s. MINSAL. Available at: https:\/\/www.minsal.cl\/portal\/url\/item\/7222754637e58646e04001011f014e64.pdf"},{"key":"bibr29-03080226231184992","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrc.2007.11.004"},{"key":"bibr30-03080226231184992","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2016.7201"},{"key":"bibr31-03080226231184992","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.2005.53221.x"},{"key":"bibr32-03080226231184992","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0b013e318232da75"},{"key":"bibr33-03080226231184992","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1016\/S1441-2772(23)02088-4","volume":"8","author":"O\u2019Brien BP","year":"2006","journal-title":"Critical Care and Resuscitation: Journal of the Australasian Academy of Critical Care Medicine"},{"key":"bibr34-03080226231184992","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-017-4860-7"},{"key":"bibr35-03080226231184992","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0b013e3182a16879"},{"key":"bibr36-03080226231184992","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.1999.tb01896.x"},{"key":"bibr37-03080226231184992","doi-asserted-by":"publisher","DOI":"10.1016\/j.iccn.2007.11.004"},{"key":"bibr38-03080226231184992","doi-asserted-by":"publisher","DOI":"10.1186\/cc10121"},{"key":"bibr39-03080226231184992","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(09)60658-9"},{"key":"bibr40-03080226231184992","doi-asserted-by":"publisher","DOI":"10.5152\/eurjrheum.2020.19043"},{"key":"bibr41-03080226231184992","doi-asserted-by":"publisher","DOI":"10.1093\/ageing\/afq022"},{"key":"bibr42-03080226231184992","doi-asserted-by":"publisher","DOI":"10.1016\/j.medin.2009.04.003"},{"key":"bibr43-03080226231184992","unstructured":"World Federation of Occupational Therapists (n.d.) About Occupational Therapy. Available at: https:\/\/wfot.org\/about\/about-occupational-therapy (accessed 7 September 2021)."},{"key":"bibr44-03080226231184992","doi-asserted-by":"publisher","DOI":"10.1097\/PHM.0b013e3181a9f1d6"},{"key":"bibr45-03080226231184992","doi-asserted-by":"publisher","DOI":"10.3389\/fpubh.2021.675523"},{"key":"bibr46-03080226231184992","volume":"17","author":"Zimmerman JE","year":"2013","journal-title":"Critical Care\/the Society of Critical Care Medicine"}],"container-title":["British Journal of Occupational Therapy"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/03080226231184992","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/03080226231184992","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/03080226231184992","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T13:20:03Z","timestamp":1777382403000},"score":1,"resource":{"primary":{"URL":"http:\/\/journals.sagepub.com\/doi\/10.1177\/03080226231184992"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,7,14]]},"references-count":46,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2023,11]]}},"alternative-id":["10.1177\/03080226231184992"],"URL":"https:\/\/doi.org\/10.1177\/03080226231184992","relation":{},"ISSN":["0308-0226","1477-6006"],"issn-type":[{"value":"0308-0226","type":"print"},{"value":"1477-6006","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,7,14]]}}}