{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T11:47:16Z","timestamp":1777376836705,"version":"3.51.4"},"reference-count":8,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2001,12,1]],"date-time":"2001-12-01T00:00:00Z","timestamp":1007164800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Anaesth Intensive Care"],"published-print":{"date-parts":[[2001,12]]},"abstract":"<jats:p>A 68-year-old woman with unstable angina and an episode of ventricular fibrillation developed a persistent and recurrent rash due to heparin. Medical therapy was continued with danaproid. For cardiopulmonary bypass and coronary artery grafting, r-hirudin was used as the anticoagulant. There were no thrombotic or coagulopathic complications. There is still no ideal alternative to unfractionated heparin for anticoagulation for cardiopulmonary bypass. The use of r-hirudin was successful and we describe our anticoagulant strategy.<\/jats:p>","DOI":"10.1177\/0310057x0102900613","type":"journal-article","created":{"date-parts":[[2019,1,14]],"date-time":"2019-01-14T14:33:13Z","timestamp":1547476393000},"page":"627-630","source":"Crossref","is-referenced-by-count":5,"title":["r-hirudin as Anticoagulant for Cardiopulmonary Bypass"],"prefix":"10.1177","volume":"29","author":[{"given":"R. J.","family":"Cameron","sequence":"first","affiliation":[{"name":"Department of Anaesthesia, Waikato Hospital, Hamilton, New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2001,12,1]]},"reference":[{"key":"bibr1-0310057X0102900613","doi-asserted-by":"publisher","DOI":"10.1055\/s-0038-1656078"},{"key":"bibr2-0310057X0102900613","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5223(19)34573-8"},{"key":"bibr3-0310057X0102900613","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1097\/00000542-199009000-00034","volume":"73","author":"Doughty D.","year":"1990","journal-title":"Anesthesiology"},{"key":"bibr4-0310057X0102900613","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-199702000-00026"},{"key":"bibr5-0310057X0102900613","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-199809000-00029"},{"key":"bibr6-0310057X0102900613","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-4975(99)01289-8"},{"key":"bibr7-0310057X0102900613","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5223(05)80033-9"},{"key":"bibr8-0310057X0102900613","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-200001000-00040"}],"container-title":["Anaesthesia and Intensive Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0310057X0102900613","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0310057X0102900613","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T09:05:54Z","timestamp":1777367154000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0310057X0102900613"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,12]]},"references-count":8,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2001,12]]}},"alternative-id":["10.1177\/0310057X0102900613"],"URL":"https:\/\/doi.org\/10.1177\/0310057x0102900613","relation":{},"ISSN":["0310-057X","1448-0271"],"issn-type":[{"value":"0310-057X","type":"print"},{"value":"1448-0271","type":"electronic"}],"subject":[],"published":{"date-parts":[[2001,12]]}}}