{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T12:06:15Z","timestamp":1777377975262,"version":"3.51.4"},"reference-count":23,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2002,8,1]],"date-time":"2002-08-01T00:00:00Z","timestamp":1028160000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Anaesth Intensive Care"],"published-print":{"date-parts":[[2002,8]]},"abstract":"<jats:p>We studied remifentanil and propofol for analgesia and sedation during the placement of an ophthalmic block. Eighty ASA I or II patients undergoing elective cataract surgery under a retrobulbar block in a rural camp setting were included in the study. Patients were randomly divided into four groups and received different drug combinations as follows: Group I\u2014remifentanil 1 \u03bcg\/kg, Group II\u2014remifentanil 0.5 \u03bcg\/kg and propofol 0.5 mg\/kg, Group III\u2014 remifentanil 1 \u03bcg\/kg with propofol 0.5 mg\/kg and Group IV\u2014saline 0.1 ml\/kg. Patients were observed for degree of movement, sedation, pain, recall and respiratory depression.<\/jats:p>\n                  <jats:p>No patient in the study groups reported pain or displayed movement whereas most of the patients in the control group had significant pain during the placement of the block. Also, seven (35%) patients in the control group showed significant movement which may have led to failure of block in two patients and retrobulbar haemorrhage in one patient. Incidence of significant respiratory depression was maximum in Group III patients (60%), followed by Group I (20%) and least in Group II (5%). All patients in the study groups remained cooperative and obeyed commands except four patients in group III (OAA\/S-4). Postoperatively, other than the control group, recall was maximum in Group I (55%) and least in Group II (5%).<\/jats:p>\n                  <jats:p>Hence, a combination of remifentanil 0.5 \u03bcg\/kg with propofol 0.5 mg\/kg as a bolus was considered to provide excellent relief of pain and anxiety with least adverse effects for the placement of ophthalmic blocks.<\/jats:p>","DOI":"10.1177\/0310057x0203000405","type":"journal-article","created":{"date-parts":[[2019,1,22]],"date-time":"2019-01-22T20:45:48Z","timestamp":1548189948000},"page":"433-437","source":"Crossref","is-referenced-by-count":21,"title":["Remifentanil and Propofol Sedation for Retrobulbar Nerve Block"],"prefix":"10.1177","volume":"30","author":[{"given":"V.","family":"Rewari","sequence":"first","affiliation":[{"name":"All India Institute of Medical Sciences, New Delhi, India"},{"name":"Assistant Professor, Department of Anaesthesiology and Intensive Care."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Madan","sequence":"additional","affiliation":[{"name":"All India Institute of Medical Sciences, New Delhi, India"},{"name":"Additional Professor, Department of Anaesthesiology and Intensive Care."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H. L.","family":"Kaul","sequence":"additional","affiliation":[{"name":"All India Institute of Medical Sciences, New Delhi, India"},{"name":"Professor and Head, Department of Anaesthesiology and Intensive Care."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Kumar","sequence":"additional","affiliation":[{"name":"All India Institute of Medical Sciences, New Delhi, India"},{"name":"Additional Professor, Dr Rajendra Prasad Centre of Ophthalmic Sciences."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2002,8,1]]},"reference":[{"key":"bibr1-0310057X0203000405","doi-asserted-by":"publisher","DOI":"10.1097\/00004311-198220010-00010"},{"key":"bibr2-0310057X0203000405","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-198105000-00008"},{"key":"bibr3-0310057X0203000405","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-198709001-00001"},{"key":"bibr4-0310057X0203000405","first-page":"518","volume":"77","author":"Quigley H.A.","year":"1984","journal-title":"Am J Ophthalmol"},{"key":"bibr5-0310057X0203000405","doi-asserted-by":"publisher","DOI":"10.1213\/00000539-198004000-00007"},{"key":"bibr6-0310057X0203000405","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-198512000-00022"},{"key":"bibr7-0310057X0203000405","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-198912000-00006"},{"key":"bibr8-0310057X0203000405","doi-asserted-by":"publisher","DOI":"10.1213\/00000539-199408000-00021"},{"key":"bibr9-0310057X0203000405","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2044.1987.tb05169.x"},{"key":"bibr10-0310057X0203000405","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-199009001-00024"},{"key":"bibr11-0310057X0203000405","doi-asserted-by":"publisher","DOI":"10.1016\/0952-8180(92)90021-R"},{"key":"bibr12-0310057X0203000405","first-page":"S164","volume":"74","author":"Kimovec M.","year":"1992","journal-title":"Anesthesiology"},{"key":"bibr13-0310057X0203000405","first-page":"S3","volume":"82","author":"Ahmad S.","year":"1996","journal-title":"Anesth Analg"},{"key":"bibr14-0310057X0203000405","first-page":"331","volume":"24","author":"Ahmad S.","year":"1999","journal-title":"Reg Anesth Pain Med"},{"key":"bibr15-0310057X0203000405","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-199311000-00002"},{"key":"bibr16-0310057X0203000405","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2346.1999.00574.x"},{"key":"bibr17-0310057X0203000405","doi-asserted-by":"publisher","DOI":"10.1016\/S0952-8180(96)00137-7"},{"key":"bibr18-0310057X0203000405","first-page":"317","volume":"82","author":"Frey K.","year":"1999","journal-title":"Anesth Analg"},{"key":"bibr19-0310057X0203000405","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/82.4.635"},{"key":"bibr20-0310057X0203000405","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1097\/00004714-199008000-00003","volume":"10","author":"Chernik D.A.","year":"1990","journal-title":"J Clin Psychopharmacol"},{"key":"bibr21-0310057X0203000405","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-199612000-00009"},{"key":"bibr22-0310057X0203000405","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-199503000-00005"},{"key":"bibr23-0310057X0203000405","doi-asserted-by":"publisher","DOI":"10.1136\/jramc-146-03-08"}],"container-title":["Anaesthesia and Intensive Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0310057X0203000405","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0310057X0203000405","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T09:09:39Z","timestamp":1777367379000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0310057X0203000405"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,8]]},"references-count":23,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2002,8]]}},"alternative-id":["10.1177\/0310057X0203000405"],"URL":"https:\/\/doi.org\/10.1177\/0310057x0203000405","relation":{},"ISSN":["0310-057X","1448-0271"],"issn-type":[{"value":"0310-057X","type":"print"},{"value":"1448-0271","type":"electronic"}],"subject":[],"published":{"date-parts":[[2002,8]]}}}