{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T11:54:38Z","timestamp":1777377278788,"version":"3.51.4"},"reference-count":30,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2008,9,1]],"date-time":"2008-09-01T00:00:00Z","timestamp":1220227200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Anaesth Intensive Care"],"published-print":{"date-parts":[[2008,9]]},"abstract":"<jats:p>Low dose local anaesthetic and fentanyl epidural solutions are commonly \u2018topped-up\u2019 for urgent caesarean section. However, the block characteristics associated with newer local anaesthetics such as ropivacaine 0.75% and levobupivacaine 0.5% have not been fully determined. In a randomised double-blinded controlled clinical trial, we compared 2% lignocaine with adrenaline and fentanyl (LAF), 0.75% ropivacaine and 0.5% levobupivacaine for extension of low dose epidural analgesia for urgent caesarean section in 90 Asian parturients.<\/jats:p>\n                  <jats:p>There was no significant difference in the median, interquartile range, time to T4 loss of sensation to cold between LAF (9.5, 7.0 to 13.3 minutes), 0.75% ropivacaine (10.0, 7.0 to 15.0 minutes) and 0.5% levobupivacaine (10.0, 7.0 to 15.0 minutes). No woman required conversion to general anaesthesia. The supplementation rate did not differ between groups. Levobupivacaine provided a longer duration of sensory block compared to LAF, but a similar duration to 0.75% ropivacaine.<\/jats:p>\n                  <jats:p>Under the conditions of this study there was no significant difference in time to surgical readiness (defined as loss of sensation to cold to T4) between LAF, 0.75% ropivacaine and 0.5% levobupivacaine groups. Ropivacaine and levobupivacaine are suitable alternatives for extending epidural analgesia for urgent caesarean section.<\/jats:p>","DOI":"10.1177\/0310057x0803600505","type":"journal-article","created":{"date-parts":[[2019,1,22]],"date-time":"2019-01-22T23:00:03Z","timestamp":1548198003000},"page":"659-664","source":"Crossref","is-referenced-by-count":18,"title":["Comparison of 2% Lignocaine with Adrenaline and Fentanyl, 0.75% Ropivacaine and 0.5% Levobupivacaine for Extension of Epidural Analgesia for Urgent Caesarean Section after Low Dose Epidural Infusion during Labour"],"prefix":"10.1177","volume":"36","author":[{"given":"B. L.","family":"Sng","sequence":"first","affiliation":[{"name":"Department of Women's Anaesthesia, KK Women s and Children s Hospital, Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L. L.","family":"Pay","sequence":"additional","affiliation":[{"name":"Department of Women's Anaesthesia, KK Women s and Children s Hospital, Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. T. 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