{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T12:17:11Z","timestamp":1782130631946,"version":"3.54.5"},"reference-count":22,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2011,1,1]],"date-time":"2011-01-01T00:00:00Z","timestamp":1293840000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Anaesth Intensive Care"],"published-print":{"date-parts":[[2011,1]]},"abstract":"<jats:p>We present a case study of a severe episode of iodine toxicity following povidone-iodine wash with clinical manifestations of cardiovascular collapse, metabolic acidosis, renal failure and seizures. Povidone-iodine has been used as a medical antiseptic and disinfectant since 1952. Iodine toxicity secondary to povidone-iodine use is rare. Iodine toxicity is difficult to diagnose and the diagnosis is made by a high index of suspicion. Toxicity due to iodine correlates with serum and urine iodine levels. Treatment of iodine toxicity is supportive.<\/jats:p>\n                  <jats:p>A review of literature relating to the components of povidone-iodine, iodine metabolism, its manifestations and management of iodine toxicity secondary to povidone-iodine is also presented. An Ovid-Medline search from 1950 to 2009 revealed 1236 articles on the clinical manifestations of povidone-iodine usage but no article on iodine toxicity relating to povidone-iodine based on the following search criteria: povidone-iodine and\/or iodine toxicity secondary to povidone-iodine (limited to English language, review articles, full text and human patients).<\/jats:p>","DOI":"10.1177\/0310057x1103900121","type":"journal-article","created":{"date-parts":[[2019,1,14]],"date-time":"2019-01-14T17:40:53Z","timestamp":1547487653000},"page":"127-130","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":17,"title":["Cardiovascular Collapse following Povidone-Iodine Wash"],"prefix":"10.1177","volume":"39","author":[{"given":"H.","family":"Ramaswamykanive","sequence":"first","affiliation":[{"name":"Intensive Care Unit, Prince of Wales Hospital, Sydney, New South Wales, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Z.","family":"Nanavati","sequence":"additional","affiliation":[{"name":"Intensive Care Unit, Prince of Wales Hospital, Sydney, New South Wales, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Mackie","sequence":"additional","affiliation":[{"name":"Intensive Care Unit, Prince of Wales Hospital, Sydney, New South Wales, Australia"},{"name":"Senior Nephrologist, Department of Nephrology and Medical Co-Director, Program of Oncology, Emergency and Medicine."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Linderman","sequence":"additional","affiliation":[{"name":"Intensive Care Unit, Prince of Wales Hospital, Sydney, New South Wales, Australia"},{"name":"Senior Haematologist, Department of Haematology, South Eastern Area Laboratory Services."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"O.","family":"Lavee","sequence":"additional","affiliation":[{"name":"Intensive Care Unit, Prince of Wales Hospital, Sydney, New South Wales, Australia"},{"name":"Registrar, Department of Haematology, South Eastern Area Laboratory Services."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2011,1,1]]},"reference":[{"key":"bibr1-0310057X1103900121","doi-asserted-by":"publisher","DOI":"10.1080\/00015458.2003.11679417"},{"key":"bibr2-0310057X1103900121","first-page":"183","volume":"176","author":"LeVeen H.H.","year":"1993","journal-title":"Surg Gynecol Obstet"},{"key":"bibr3-0310057X1103900121","doi-asserted-by":"publisher","DOI":"10.1093\/ptj\/78.2.212"},{"key":"bibr4-0310057X1103900121","volume-title":"Greenspan's Basic and Clinical Endocrinology (e-book), 8th ed.","author":"Cooper D.S.","year":"2007"},{"key":"bibr5-0310057X1103900121","unstructured":"Expert group on vitamins and minerals revised review of iodine. From www.food.gov.uk\/multimedia\/pdfs\/evm0006p.pdf Accessed September 2009."},{"key":"bibr6-0310057X1103900121","unstructured":"PVP-IODINE Brochure. From http:\/\/www.pharmyaring.com\/pic\/p_091204132009.pdf Accessed May 2010."},{"key":"bibr7-0310057X1103900121","doi-asserted-by":"publisher","DOI":"10.1097\/00005373-199003000-00019"},{"key":"bibr8-0310057X1103900121","first-page":"410","volume":"29","author":"Campistol J.M.","year":"1988","journal-title":"J Cardiovasc Surg (Torino)"},{"key":"bibr9-0310057X1103900121","first-page":"274","author":"Higgins D.G.","year":"1975","journal-title":"Chemist and Druggist"},{"key":"bibr10-0310057X1103900121","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9610(86)90477-0"},{"key":"bibr11-0310057X1103900121","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.15.4.635-639.1982"},{"key":"bibr12-0310057X1103900121","doi-asserted-by":"publisher","DOI":"10.3109\/15563659609013776"},{"key":"bibr13-0310057X1103900121","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-4975(10)61965-0"},{"key":"bibr14-0310057X1103900121","doi-asserted-by":"publisher","DOI":"10.1097\/00000441-198005000-00007"},{"key":"bibr15-0310057X1103900121","doi-asserted-by":"publisher","DOI":"10.1093\/clinchem\/46.4.529"},{"key":"bibr16-0310057X1103900121","first-page":"704","volume":"120","author":"Dyck R.F.","year":"1979","journal-title":"Can Med Assoc J"},{"key":"bibr17-0310057X1103900121","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(76)91406-9"},{"key":"bibr18-0310057X1103900121","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199206253262617"},{"key":"bibr19-0310057X1103900121","doi-asserted-by":"publisher","DOI":"10.1016\/0022-3468(90)90531-D"},{"key":"bibr20-0310057X1103900121","doi-asserted-by":"publisher","DOI":"10.1002\/cpt1975173355"},{"key":"bibr21-0310057X1103900121","first-page":"43","volume":"146","author":"Cruz F.D.","year":"1987","journal-title":"West J Med"},{"key":"bibr22-0310057X1103900121","first-page":"727","volume":"25","author":"Shelanski HA","year":"1956","journal-title":"J Int Coll Surg"}],"container-title":["Anaesthesia and Intensive Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0310057X1103900121","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0310057X1103900121","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T09:08:56Z","timestamp":1777367336000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0310057X1103900121"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,1]]},"references-count":22,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2011,1]]}},"alternative-id":["10.1177\/0310057X1103900121"],"URL":"https:\/\/doi.org\/10.1177\/0310057x1103900121","relation":{},"ISSN":["0310-057X","1448-0271"],"issn-type":[{"value":"0310-057X","type":"print"},{"value":"1448-0271","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,1]]}}}