{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T03:25:57Z","timestamp":1791257157947,"version":"4.1.0"},"reference-count":15,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2011,5,1]],"date-time":"2011-05-01T00:00:00Z","timestamp":1304208000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Anaesth Intensive Care"],"published-print":{"date-parts":[[2011,5]]},"abstract":"<jats:p>\n                    A patient undergoing anaesthesia for coronary artery bypass surgery developed what was subsequently confirmed to be an anaphylactic reaction to succinylated gelatin (Gelofusine\n                    <jats:sup>\u00ae<\/jats:sup>\n                    ). By virtue of being on cardiopulmonary bypass, rapid detection, quantification and treatment of volume loss (by vasodilatation and extravasation) was possible. The patient required 51 ml\/kg of resuscitative fluids in the 15 minutes after onset of anaphylaxis, or 73% of her calculated preoperative blood volume. Alpha-adrenoceptor agonists and vasopressin were required to manage ongoing vasoplegia. This case emphasises the importance of volume resuscitation and vasopressors in the treatment of anaphylaxis.\n                  <\/jats:p>","DOI":"10.1177\/0310057x1103900324","type":"journal-article","created":{"date-parts":[[2019,1,22]],"date-time":"2019-01-22T23:34:53Z","timestamp":1548200093000},"page":"492-495","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":27,"title":["Quantification of Volume Loss and Haemodynamic Changes of Gelofusine\u00ae-induced Anaphylaxis during Cardiopulmonary Bypass"],"prefix":"10.1177","volume":"39","author":[{"given":"R.","family":"Clarke","sequence":"first","affiliation":[{"name":"Sir Charles Gairdner Hospital."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Sadleir","sequence":"additional","affiliation":[{"name":"Departments of Anaesthesia, Sir Charles Gairdner Hospital, Nedlands and Fremantle Hospital, Perth, Western Australia"},{"name":"Sir Charles Gairdner Hospital."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. W.","family":"Van Niekerk","sequence":"additional","affiliation":[{"name":"Departments of Anaesthesia, Sir Charles Gairdner Hospital, Nedlands and Fremantle Hospital, Perth, Western Australia"},{"name":"Freemantle Hospital."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Platt","sequence":"additional","affiliation":[{"name":"Departments of Anaesthesia, Sir Charles Gairdner Hospital, Nedlands and Fremantle Hospital, Perth, Western Australia"},{"name":"Sir Charles Gairdner Hospital."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2011,5,1]]},"reference":[{"key":"bibr1-0310057X1103900324","doi-asserted-by":"publisher","DOI":"10.1097\/01.all.0000174158.78626.35"},{"key":"bibr2-0310057X1103900324","doi-asserted-by":"publisher","DOI":"10.1177\/0310057X8401200205"},{"key":"bibr3-0310057X1103900324","doi-asserted-by":"publisher","DOI":"10.1177\/0310057X8000800208"},{"key":"bibr4-0310057X1103900324","first-page":"206","volume":"84","author":"Jenkins S.","year":"2002","journal-title":"Ann R Coll Surg Engl"},{"key":"bibr5-0310057X1103900324","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2044.1994.tb03515.x"},{"key":"bibr6-0310057X1103900324","doi-asserted-by":"publisher","DOI":"10.1177\/0310057X0203000415"},{"key":"bibr7-0310057X1103900324","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(77)91953-5"},{"key":"bibr8-0310057X1103900324","doi-asserted-by":"publisher","DOI":"10.1213\/01.ANE.0000052711.68903.5D"},{"key":"bibr9-0310057X1103900324","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1111\/j.1742-6723.2006.00831.x","volume":"18","author":"Brown S.G.A.","year":"2006","journal-title":"Emerg Med Australas"},{"key":"bibr10-0310057X1103900324","doi-asserted-by":"publisher","DOI":"10.1016\/j.iac.2007.03.003"},{"key":"bibr11-0310057X1103900324","doi-asserted-by":"publisher","DOI":"10.1177\/0310057X8601400105"},{"key":"bibr12-0310057X1103900324","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2005.12.1303"},{"key":"bibr13-0310057X1103900324","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.63.1.210"},{"key":"bibr14-0310057X1103900324","doi-asserted-by":"crossref","first-page":"1082","DOI":"10.1111\/j.1365-2044.2001.02268.x","volume":"56","author":"McBrien M.E.","year":"2001","journal-title":"Anaesthesia"},{"key":"bibr15-0310057X1103900324","doi-asserted-by":"publisher","DOI":"10.1213\/ane.0b013e3181770b42"}],"container-title":["Anaesthesia and Intensive Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0310057X1103900324","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0310057X1103900324","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T09:09:10Z","timestamp":1777367350000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0310057X1103900324"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,5]]},"references-count":15,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2011,5]]}},"alternative-id":["10.1177\/0310057X1103900324"],"URL":"https:\/\/doi.org\/10.1177\/0310057x1103900324","relation":{},"ISSN":["0310-057X","1448-0271"],"issn-type":[{"value":"0310-057X","type":"print"},{"value":"1448-0271","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,5]]}}}