{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T11:53:21Z","timestamp":1777377201819,"version":"3.51.4"},"reference-count":20,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Anaesth Intensive Care"],"published-print":{"date-parts":[[2012,1]]},"abstract":"<jats:p>\n                    In order to reduce postoperative opioid requirement, extrapleural local anaesthetic infusion dosing recommendations and guidelines for extrapleural catheter insertion were developed in our institution for \u2018extubatable\u2019 neonates requiring short-gap neonatal tracheo-oesophageal fistula\/oesophageal atresia repair (via thoracotomy) and audited prospectively. Data audited included patient characteristics, analgesia details and ventilation duration. We divided patients into two groups: group 1 \u2013 term patients (&gt;36 weeks gestational age) with birth-weights &gt;2.5 kg; group 2 \u2013 pre-term patients (&lt;36 weeks gestational age), with birth weights &lt;2.5 kg and those with co-morbidities. There were 26 neonates in group 1 and 11 in group 2. All received extrapleural infusions of bupivacaine or levobupivacaine: the majority (90%) &lt;300 \u03bcg.kg\n                    <jats:sup>\u22121<\/jats:sup>\n                    .hour\n                    <jats:sup>\u22121<\/jats:sup>\n                    (median duration 43 hours, range 1.5 to 72 hours); 36% required morphine infusion and 39% were ventilated (median duration 34 hours, range 3 to 140 hours). In group 1, 24% required morphine infusion compared with 64% in group 2. Most group 1 patients (77%) were extubated immediately postoperatively; 20% had short duration ventilation (median 15 hours, range 11 to 37 hours); one required longer-term ventilation (231 hours). 82% of group 2 were ventilated for a median of 72 hours (range 3 to 140 hours). Review of patients\u2019 co-morbidities facilitated guideline revision. These now specify use in neonates requiring short-gap tracheo-oesophageal fistula\/oesophageal atresia repair who are term at &gt;36 weeks gestational age and &gt;2.5 kg birth-weight, anticipated as ready for extubation either immediately or shortly after surgery.\n                  <\/jats:p>","DOI":"10.1177\/0310057x1204000122","type":"journal-article","created":{"date-parts":[[2019,1,22]],"date-time":"2019-01-22T23:53:38Z","timestamp":1548201218000},"page":"172-180","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Audit of Extrapleural Local Anaesthetic Infusion in Neonates following Repair of Tracheo-Oesophageal Fistulae and Oesophageal Atresia via Thoracotomy"],"prefix":"10.1177","volume":"40","author":[{"given":"G. M.","family":"Palmer","sequence":"first","affiliation":[{"name":"Department of Anaesthesia and Pain Management, Royal Children's Hospital, Melbourne, Victoria, Australia"},{"name":"Children's Pain Management Service, Department of Anaesthesia and Pain Management, Royal Children's Hospital, Murdoch Childrens Research Institute and University of Melbourne."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Thalayasingam","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia and Pain Management, Royal Children's Hospital, Melbourne, Victoria, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C. M.","family":"Mcnally","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia and Pain Management, Royal Children's Hospital, Melbourne, Victoria, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D. G.","family":"Tingay","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia and Pain Management, Royal Children's Hospital, Melbourne, Victoria, Australia"},{"name":"Department of Neonatology, Royal Children's Hospital; Murdoch Childrens Research Institute and Department of Paediatrics, University of Melbourne."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K. R.","family":"Smith","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia and Pain Management, Royal Children's Hospital, Melbourne, Victoria, Australia"},{"name":"Murdoch Childrens Research Institute."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T. D.","family":"Clarnette","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia and Pain Management, Royal Children's Hospital, Melbourne, Victoria, Australia"},{"name":"Department of General Surgery, Royal Children's Hospital."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Penrose","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia and Pain Management, Royal Children's Hospital, Melbourne, Victoria, Australia"},{"name":"Clinical Nurse Consultant, Children's Pain Management Service."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S. J.","family":"Dowden","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia and Pain Management, Royal Children's Hospital, Melbourne, Victoria, Australia"},{"name":"Clinical Nurse Consultant, Children's Pain Management Service."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G. A.","family":"Chalkiadis","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia and Pain Management, Royal Children's Hospital, Melbourne, Victoria, Australia"},{"name":"Children's Pain Management Service, Department of Paediatric Anaesthesia and Pain Management, Royal Children's Hospital; Murdoch Childrens Research Institute and Department of Paediatrics, University of Melbourne."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2012,1,1]]},"reference":[{"key":"bibr1-0310057X1204000122","doi-asserted-by":"publisher","DOI":"10.1007\/BF00182210"},{"key":"bibr2-0310057X1204000122","doi-asserted-by":"publisher","DOI":"10.1016\/0022-3468(92)90444-C"},{"key":"bibr3-0310057X1204000122","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/76.6.811"},{"key":"bibr4-0310057X1204000122","doi-asserted-by":"publisher","DOI":"10.1177\/0310057X9702500412"},{"key":"bibr5-0310057X1204000122","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/79.1.9"},{"key":"bibr6-0310057X1204000122","doi-asserted-by":"publisher","DOI":"10.1111\/j.1460-9592.1996.tb00454.x"},{"key":"bibr7-0310057X1204000122","doi-asserted-by":"publisher","DOI":"10.1016\/0022-3468(93)90432-K"},{"key":"bibr8-0310057X1204000122","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3468(88)80339-7"},{"key":"bibr9-0310057X1204000122","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-198808000-00019"},{"key":"bibr10-0310057X1204000122","doi-asserted-by":"publisher","DOI":"10.1213\/00000539-199208000-00023"},{"key":"bibr11-0310057X1204000122","doi-asserted-by":"publisher","DOI":"10.1213\/00000539-199208000-00002"},{"key":"bibr12-0310057X1204000122","doi-asserted-by":"publisher","DOI":"10.1177\/0884217504272810"},{"key":"bibr13-0310057X1204000122","doi-asserted-by":"publisher","DOI":"10.1213\/00000539-199101000-00019"},{"key":"bibr14-0310057X1204000122","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-197905000-00013"},{"key":"bibr15-0310057X1204000122","doi-asserted-by":"publisher","DOI":"10.2165\/00128072-200204100-00003"},{"key":"bibr16-0310057X1204000122","doi-asserted-by":"publisher","DOI":"10.1111\/j.1460-9592.1995.tb00285.x"},{"key":"bibr17-0310057X1204000122","doi-asserted-by":"publisher","DOI":"10.1213\/00000539-199804000-00023"},{"key":"bibr18-0310057X1204000122","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-200104000-00009"},{"key":"bibr19-0310057X1204000122","doi-asserted-by":"publisher","DOI":"10.1111\/j.1460-9592.2005.01778.x"},{"key":"bibr20-0310057X1204000122","first-page":"239","volume":"21","author":"Sakuragi T.","year":"1996","journal-title":"Reg Anesth"}],"container-title":["Anaesthesia and Intensive Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0310057X1204000122","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0310057X1204000122","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T09:06:57Z","timestamp":1777367217000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0310057X1204000122"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,1]]},"references-count":20,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2012,1]]}},"alternative-id":["10.1177\/0310057X1204000122"],"URL":"https:\/\/doi.org\/10.1177\/0310057x1204000122","relation":{},"ISSN":["0310-057X","1448-0271"],"issn-type":[{"value":"0310-057X","type":"print"},{"value":"1448-0271","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,1]]}}}