{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T16:39:00Z","timestamp":1790008740093,"version":"4.0.1"},"reference-count":14,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Anaesth Intensive Care"],"published-print":{"date-parts":[[2014,1]]},"abstract":"<jats:p>We describe a case of a patient undergoing open abdominal aneurysm surgery who developed a severe, life-threatening allergic reaction immediately after administration of sugammadex. The manifestation was purely a cardiovascular collapse. The mainstay of treatment was administration of high-dose adrenaline and fluid resuscitation. The diagnosis of anaphylaxis was supported by a positive serum mast cell tryptase (93 \u03bcg\/1) at one hour post-event. Sugammadex was confirmed as the cause of the anaphylaxis by a positive intradermal allergy test (25 mm diameter response to 1:100 dilution), with a normal saline control and a negative response to the other drugs used during the event. This case report is a reminder that the use of sugammadex is associated with rare but serious risks.<\/jats:p>","DOI":"10.1177\/0310057x1404200115","type":"journal-article","created":{"date-parts":[[2019,1,14]],"date-time":"2019-01-14T17:44:04Z","timestamp":1547487844000},"page":"89-92","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":24,"title":["Sugammadex Hypersensitivity\u2014A Case of Anaphylaxis"],"prefix":"10.1177","volume":"42","author":[{"given":"J.","family":"Jeyadoss","sequence":"first","affiliation":[{"name":"Department of Anaesthesia, The Queen Elizabeth Hospital, Woodville, South Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Kuruppu","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia, The Queen Elizabeth Hospital, Woodville, South Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.","family":"Nanjappa","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia, The Queen Elizabeth Hospital, Woodville, South Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R. 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