{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T12:09:43Z","timestamp":1777378183640,"version":"3.51.4"},"reference-count":21,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[1981,11,1]],"date-time":"1981-11-01T00:00:00Z","timestamp":373420800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Anaesth Intensive Care"],"published-print":{"date-parts":[[1981,11]]},"abstract":"<jats:p>\n                    The respiratory and haemodynamic effects of incremental levels of positive end expiratory pressure (PEEP) to 9 cm H\n                    <jats:sub>2<\/jats:sub>\n                    O were studied in ten adult patients 3-6 hours after uneventful cardiopulmonary bypass surgery. Functional residual capacity was increased and deadspace-tidal volume ratio tended to fall, the latter approaching significance at +6 and +9 cm PEEP. Thus lung volume was increased and there was a tendency to improved gas distribution to the alveoli. However there was no significant change in P\n                    <jats:sub>a<\/jats:sub>\n                    O\n                    <jats:sub>2<\/jats:sub>\n                    , alveolar-arterial oxygen tension difference or venous admixture. Cardiac index, and left ventricular strokework index were marginally depressed at 6 cm PEEP and further at 9 cm, while right atrial pressure and pulmonary artery occlusion pressure were raised at 9 cm PEEP. It would appear that low levels (3-6 cm) of PEEP do not improve gas exchange in the lungs to any worthwhile degree, and levels (6-9 cm) may impair cardiac performance.\n                  <\/jats:p>","DOI":"10.1177\/0310057x8100900401","type":"journal-article","created":{"date-parts":[[2019,1,14]],"date-time":"2019-01-14T09:16:07Z","timestamp":1547457367000},"page":"307-313","source":"Crossref","is-referenced-by-count":9,"title":["Respiratory and Cardiovascular Responses to PEEP in Artificially Ventilated Patients after Cardiopulmonary Bypass Surgery"],"prefix":"10.1177","volume":"9","author":[{"given":"T. L.","family":"Dobbinson","sequence":"first","affiliation":[{"name":"Department of Anaesthesia, University of Otago"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. R.","family":"Miller","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia, University of Otago"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1981,11,1]]},"reference":[{"key":"bibr1-0310057X8100900401","doi-asserted-by":"publisher","DOI":"10.1213\/00000539-197709000-00019"},{"key":"bibr2-0310057X8100900401","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-4975(10)61872-3"},{"key":"bibr3-0310057X8100900401","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5223(19)41169-0"},{"key":"bibr4-0310057X8100900401","doi-asserted-by":"publisher","DOI":"10.1378\/chest.76.4.397"},{"key":"bibr5-0310057X8100900401","doi-asserted-by":"publisher","DOI":"10.1097\/00003246-197503000-00003"},{"key":"bibr6-0310057X8100900401","doi-asserted-by":"publisher","DOI":"10.1097\/00005373-197511000-00002"},{"key":"bibr7-0310057X8100900401","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-197501000-00009"},{"key":"bibr8-0310057X8100900401","doi-asserted-by":"publisher","DOI":"10.1378\/chest.76.3.248"},{"key":"bibr9-0310057X8100900401","unstructured":"NunnJ.F. 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