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In patients and animals the technique has usually resulted in rapid improvement in the radiographic appearance and lung function.\n                  <\/jats:p>\n                  <jats:p>There are several possible mechanisms by which the technique may facilitate lung repair, including improvement of lung tissue oxygenation, the avoidance of high airway pressures and regional alkalosis in the lung, a reduction in oxygen toxicity, and the frequently observed reduction in pulmonary artery pressure.<\/jats:p>\n                  <jats:p>The apparent effectiveness of the technique and other associated evidence have implications which should lead us to reconsider some aspects of our conventional management of patients with severe ARDS.<\/jats:p>","DOI":"10.1177\/0310057x8601400111","type":"journal-article","created":{"date-parts":[[2019,1,16]],"date-time":"2019-01-16T03:45:18Z","timestamp":1547610318000},"page":"46-53","source":"Crossref","is-referenced-by-count":19,"title":["Extracorporeal CO\n                    <sub>2<\/sub>\n                    Removal in Severe Adult Respiratory Distress Syndrome"],"prefix":"10.1177","volume":"14","author":[{"given":"K. G.","family":"Hickling","sequence":"first","affiliation":[{"name":"Department of Intensive Care, Christchurch Hospital, New Zealand"},{"name":"Head, Department of Intensive Care."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1986,2,1]]},"reference":[{"key":"bibr1-0310057X8601400111","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1979.03300200023016"},{"key":"bibr2-0310057X8601400111","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(80)90237-8"},{"key":"bibr3-0310057X8601400111","unstructured":"GattinoniL. Extracorporeal carbon dioxide elimination in severe respiratory failure. 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