{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T12:02:25Z","timestamp":1777377745760,"version":"3.51.4"},"reference-count":13,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[1990,5,1]],"date-time":"1990-05-01T00:00:00Z","timestamp":641520000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Anaesth Intensive Care"],"published-print":{"date-parts":[[1990,5]]},"abstract":"<jats:p>As part of a program of postmarketing surveillance, the use of flumazenil was monitored prospectively in a New Zealand public hospital for a period of twelve months. A questionnaire on usage, efficacy and side-effects was completed by clinicians for 118 patients receiving the drug.<\/jats:p>\n                  <jats:p>Our conclusions are these:<\/jats:p>\n                  <jats:p>1. Flumazenil was used most frequently after anaesthesia and in the initial management of intentional drug overdose.<\/jats:p>\n                  <jats:p>2. In two-thirds of cases, flumazenil was used to antagonise benzodiazepines in the presence of non-benzodiazepine drugs and its efficacy was primarily determined by the presence of these latter drugs.<\/jats:p>\n                  <jats:p>3. The complications of flumazenil are mild although important complications may arise from interaction with other drugs and unmasking of conditions such as postoperative pain.<\/jats:p>\n                  <jats:p>4. Resedation was common (24%), although rarely a problem unless large doses of benzodiazepine agonist had been administered or if other hypnosedatives were given subsequently.<\/jats:p>","DOI":"10.1177\/0310057x9001800213","type":"journal-article","created":{"date-parts":[[2019,1,14]],"date-time":"2019-01-14T09:59:51Z","timestamp":1547459991000},"page":"229-233","source":"Crossref","is-referenced-by-count":3,"title":["Flumazenil: A Twelve-Month Survey of Use in a New Zealand Public Hospital"],"prefix":"10.1177","volume":"18","author":[{"given":"D. C.","family":"Galletly","sequence":"first","affiliation":[{"name":"Wellington School of Medicine, and Wellington Hospital, Wellington, New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Ure","sequence":"additional","affiliation":[{"name":"Wellington School of Medicine, and Wellington Hospital, Wellington, New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Turley","sequence":"additional","affiliation":[{"name":"Wellington School of Medicine, and Wellington Hospital, Wellington, New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1990,5,1]]},"reference":[{"key":"bibr1-0310057X9001800213","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-198209001-00326"},{"issue":"2","key":"bibr2-0310057X9001800213","first-page":"81","author":"Dunton A.W.","year":"1988","journal-title":"Eur J Anaesth"},{"key":"bibr3-0310057X9001800213","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/59.4.459"},{"issue":"2","key":"bibr4-0310057X9001800213","first-page":"325","author":"Geller E.","year":"1988","journal-title":"Eur J Anaesth"},{"key":"bibr5-0310057X9001800213","doi-asserted-by":"publisher","DOI":"10.1126\/science.3022383"},{"key":"bibr6-0310057X9001800213","first-page":"97","author":"Haefely W.","year":"1986","journal-title":"Alan R Liss, New York"},{"key":"bibr7-0310057X9001800213","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2125.1986.tb02912.x"},{"key":"bibr8-0310057X9001800213","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.296.6628.1070-e"},{"key":"bibr9-0310057X9001800213","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-198709001-00534"},{"key":"bibr10-0310057X9001800213","doi-asserted-by":"publisher","DOI":"10.1213\/00000539-198802001-00152"},{"key":"bibr11-0310057X9001800213","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0750-7658(87)80001-1","volume":"6","author":"Rouller M.","year":"1987","journal-title":"Ann Fr Anesth Reanim"},{"issue":"2","key":"bibr12-0310057X9001800213","first-page":"279","author":"Radakovic D.","year":"1988","journal-title":"Eur J Anaesth"},{"key":"bibr13-0310057X9001800213","first-page":"113","volume":"4","author":"Jensen S.","year":"1987","journal-title":"Eur J Anesthesiol"}],"container-title":["Anaesthesia and Intensive Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0310057X9001800213","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0310057X9001800213","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T09:08:41Z","timestamp":1777367321000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0310057X9001800213"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1990,5]]},"references-count":13,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1990,5]]}},"alternative-id":["10.1177\/0310057X9001800213"],"URL":"https:\/\/doi.org\/10.1177\/0310057x9001800213","relation":{},"ISSN":["0310-057X","1448-0271"],"issn-type":[{"value":"0310-057X","type":"print"},{"value":"1448-0271","type":"electronic"}],"subject":[],"published":{"date-parts":[[1990,5]]}}}