{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T11:49:41Z","timestamp":1777376981483,"version":"3.51.4"},"reference-count":25,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[1994,4,1]],"date-time":"1994-04-01T00:00:00Z","timestamp":765158400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Anaesth Intensive Care"],"published-print":{"date-parts":[[1994,4]]},"abstract":"<jats:p>We studied the efficacy and safety of intravenous ondansetron 4 mg for the prevention of postoperative nausea and vomiting after minor gynaecological laparoscopic surgery in Oriental women. This double-blind randomised study compared ondansetron with placebo, given before the induction of anaesthesia. The anaesthetic technique used thiopentone, fentanyl, atracurium, nitrous oxide and isoflurane. Patients were studied for 24 h with nausea assessed using a verbal numeric scale from 0-10 and emetic episodes recorded as they occurred.<\/jats:p>\n                  <jats:p>Results were available for 102 patients in each group. In the first postoperative hour, fewer patients in the ondansetron Group (12%) had emetic episodes compared with the placebo group (33%, P &lt;0.01). Nausea score over the first hour (sum of three readings at 0, 30 and 60 min) was lower in the ondansetron group (median 1.6) compared with the placebo group (3.1, P &lt;0.05). Over the 24 h period, fewer patients in the ondansetron group had emetic episodes (25%) or nausea (43%) compared with patients in the placebo group (56%, P &lt;0.01) and (58%, P &lt;0.05) respectively. No adverse events were seen.<\/jats:p>\n                  <jats:p>Ondansetron 4 mg was more effective than placebo in preventing postoperative nausea and vomiting throughout the 24 h after minor laparoscopic surgery.<\/jats:p>","DOI":"10.1177\/0310057x9402200203","type":"journal-article","created":{"date-parts":[[2019,1,14]],"date-time":"2019-01-14T12:12:21Z","timestamp":1547467941000},"page":"142-146","source":"Crossref","is-referenced-by-count":27,"title":["Ondansetron 4 mg for the Prevention of Nausea and Vomiting after Minor Laparoscopic Gynaecological Surgery"],"prefix":"10.1177","volume":"22","author":[{"given":"T. K. L.","family":"Suen","sequence":"first","affiliation":[{"name":"Department of Anaesthesia and Intensive Care, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, N.T., Hong Kong"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T. A.","family":"Gin","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia and Intensive Care, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, N.T., Hong Kong"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P. P.","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia and Intensive Care, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, N.T., Hong Kong"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Y. M.","family":"Rowbottom","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia and Intensive Care, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, N.T., Hong Kong"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L. A. H.","family":"Critchley","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia and Intensive Care, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, N.T., Hong Kong"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. K.","family":"Ray","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia and Intensive Care, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, N.T., Hong Kong"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1994,4,1]]},"reference":[{"key":"bibr1-0310057X9402200203","first-page":"651","author":"Editorial.","year":"1989","journal-title":"Lancet"},{"key":"bibr2-0310057X9402200203","doi-asserted-by":"publisher","DOI":"10.1213\/00000539-199109000-00001"},{"key":"bibr3-0310057X9402200203","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-199207000-00023"},{"key":"bibr4-0310057X9402200203","doi-asserted-by":"publisher","DOI":"10.2165\/00003495-199141040-00006"},{"key":"bibr5-0310057X9402200203","doi-asserted-by":"publisher","DOI":"10.1213\/00000539-199106000-00005"},{"key":"bibr6-0310057X9402200203","doi-asserted-by":"publisher","DOI":"10.1213\/00000539-199109000-00002"},{"key":"bibr7-0310057X9402200203","doi-asserted-by":"publisher","DOI":"10.1213\/00000539-199109000-00003"},{"key":"bibr8-0310057X9402200203","doi-asserted-by":"publisher","DOI":"10.1016\/0952-8180(93)90083-Q"},{"key":"bibr9-0310057X9402200203","doi-asserted-by":"publisher","DOI":"10.1016\/0952-8180(93)90084-R"},{"key":"bibr10-0310057X9402200203","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2044.1993.tb06904.x"},{"key":"bibr11-0310057X9402200203","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/68.5.466"},{"key":"bibr12-0310057X9402200203","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-199301000-00005"},{"key":"bibr13-0310057X9402200203","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/70.2.135"},{"key":"bibr14-0310057X9402200203","doi-asserted-by":"publisher","DOI":"10.1007\/BF03036963"},{"key":"bibr15-0310057X9402200203","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-199302000-00010"},{"key":"bibr16-0310057X9402200203","doi-asserted-by":"crossref","first-page":"320P","DOI":"10.1093\/bja\/71.5.773","volume":"71","author":"McDonald P.J.","year":"1993","journal-title":"Br J Anaesth"},{"key":"bibr17-0310057X9402200203","doi-asserted-by":"publisher","DOI":"10.1007\/BF03009516"},{"key":"bibr18-0310057X9402200203","doi-asserted-by":"publisher","DOI":"10.1213\/00000539-199210000-00017"},{"issue":"1","key":"bibr19-0310057X9402200203","first-page":"A12","volume":"70","author":"Alon E.","year":"1993","journal-title":"Br J Anaesth"},{"issue":"1","key":"bibr20-0310057X9402200203","first-page":"A13","volume":"70","author":"Gan T.J.","year":"1993","journal-title":"Br J Anaesth"},{"issue":"1","key":"bibr21-0310057X9402200203","first-page":"A14","volume":"70","author":"Geiger C.","year":"1993","journal-title":"Br J Anaesth"},{"key":"bibr22-0310057X9402200203","first-page":"S350","volume":"76","author":"Roberson C.R.","year":"1993","journal-title":"Anesth Analg"},{"key":"bibr23-0310057X9402200203","first-page":"S329","volume":"76","author":"Peterson M.D.","year":"1993","journal-title":"Anesth Analg"},{"issue":"1","key":"bibr24-0310057X9402200203","first-page":"A2","volume":"70","author":"Morris R.W.","year":"1993","journal-title":"Br J Anaesth"},{"key":"bibr25-0310057X9402200203","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-199301000-00004"}],"container-title":["Anaesthesia and Intensive Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0310057X9402200203","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0310057X9402200203","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T09:06:21Z","timestamp":1777367181000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0310057X9402200203"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1994,4]]},"references-count":25,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1994,4]]}},"alternative-id":["10.1177\/0310057X9402200203"],"URL":"https:\/\/doi.org\/10.1177\/0310057x9402200203","relation":{},"ISSN":["0310-057X","1448-0271"],"issn-type":[{"value":"0310-057X","type":"print"},{"value":"1448-0271","type":"electronic"}],"subject":[],"published":{"date-parts":[[1994,4]]}}}