{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T11:57:15Z","timestamp":1777377435018,"version":"3.51.4"},"reference-count":21,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[1996,2,1]],"date-time":"1996-02-01T00:00:00Z","timestamp":823132800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Anaesth Intensive Care"],"published-print":{"date-parts":[[1996,2]]},"abstract":"<jats:p>We aimed to evaluate the tonometer in the assessment of gastrointestinal ischaemia induced by an infrarenal aortic cross-clamp. Nine anaesthetized pigs were cannulated for haemodynamic monitoring and radionuclide labelled microsphere (RLM) injection. Gastric and sigmoid tonometers were positioned. After haemodynamic stabilization an infrarenal aortic cross-clamp was applied. Animals were sacrificed at the completion of the study and tissue sampled from the stomach and sigmoid colon for regional blood flow measurements. Measurements were made pre-clamp, post-clamp, pre-release and post-release. Haemodynamic parameters, gastric intramucosal pH (pHi) and blood flow did not change throughout the experiment. Arterial pH increased during cross-clamp and returned to baseline post-release. Arterial bicarbonate fell post release. Sigmoid blood flow fell during cross-clamp. The sigmoid pHi fall, delayed until pre-release, remained low post-release. Although there was a consistent fall in sigmoid pHi, 63% of post-clamp values remained within the baseline range. We conclude that maintaining haemodynamic parameters around baseline values resulted in maintenance of gastric mucosal perfusion as indicated by a steady gastric pHi. However, below the aortic cross-clamp, delay between change in sigmoid colon blood flow and change in pHi and wide variation in sigmoid pHi limits the value of an individual pHi measurement in detecting ischaemia.<\/jats:p>","DOI":"10.1177\/0310057x9602400103","type":"journal-article","created":{"date-parts":[[2019,1,14]],"date-time":"2019-01-14T13:34:48Z","timestamp":1547472888000},"page":"15-19","source":"Crossref","is-referenced-by-count":2,"title":["An Assessment of Tonometry and Regional Splanchnic Blood Flow during Aortic Cross-Clamping in the Pig"],"prefix":"10.1177","volume":"24","author":[{"given":"T.","family":"Jacques","sequence":"first","affiliation":[{"name":"Departments of Intensive Care, Anaesthetics and Vascular Surgery, The St George Hospital, Sydney, N.S.W"},{"name":"Department of Intensive Care."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Morris","sequence":"additional","affiliation":[{"name":"Departments of Intensive Care, Anaesthetics and Vascular Surgery, The St George Hospital, Sydney, N.S.W"},{"name":"Department of Anaesthetics."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N.","family":"Lalak","sequence":"additional","affiliation":[{"name":"Departments of Intensive Care, Anaesthetics and Vascular Surgery, The St George Hospital, Sydney, N.S.W"},{"name":"Department of Vascular Surgery."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Englund","sequence":"additional","affiliation":[{"name":"Departments of Intensive Care, Anaesthetics and Vascular Surgery, The St George Hospital, Sydney, N.S.W"},{"name":"Department of Vascular Surgery."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Gibb","sequence":"additional","affiliation":[{"name":"Departments of Intensive Care, Anaesthetics and Vascular Surgery, The St George Hospital, Sydney, N.S.W"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1996,2,1]]},"reference":[{"key":"bibr1-0310057X9602400103","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.1986.01400060048005"},{"key":"bibr2-0310057X9602400103","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.1987.01400200031004"},{"key":"bibr3-0310057X9602400103","doi-asserted-by":"publisher","DOI":"10.1097\/00003246-198709000-00007"},{"key":"bibr4-0310057X9602400103","first-page":"519","volume":"259","author":"Antonsson JB","year":"1990","journal-title":"Am J Physiol"},{"key":"bibr5-0310057X9602400103","first-page":"235","volume":"2","author":"Swindle MM.","journal-title":"Swine in Biomedical Research"},{"key":"bibr6-0310057X9602400103","unstructured":"LoewFM. Selection of experimental animal models. In: GrangerDN, BulkleyGB, eds. Measurement of Blood Flow. Williams and Wilkins, Baltimore 1981; 49\u201355."},{"key":"bibr7-0310057X9602400103","doi-asserted-by":"publisher","DOI":"10.1016\/0022-4804(82)90007-5"},{"key":"bibr8-0310057X9602400103","first-page":"60","volume":"9","author":"Fiddian-Green RG.","year":"1992","journal-title":"Intensive Care World"},{"key":"bibr9-0310057X9602400103","doi-asserted-by":"crossref","unstructured":"LevineBA, SirinekKR, GaskillHV. The radiolabeled microsphere technique in gut blood flow measurement\u2014current practice. 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