{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T11:58:14Z","timestamp":1777377494992,"version":"3.51.4"},"reference-count":34,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[1996,4,1]],"date-time":"1996-04-01T00:00:00Z","timestamp":828316800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Anaesth Intensive Care"],"published-print":{"date-parts":[[1996,4]]},"abstract":"<jats:p>Management of severe malaria is an increasing problem worldwide. This paper reviews the pathophysiology and management documenting two years\u2019 experience of admissions of severe malaria to an ICU in a non-endemic area.<\/jats:p>\n                  <jats:p>Clinical and laboratory features of severe malaria were analysed for predictors of mortality. Twenty-eight patients had clinical or laboratory features compatible with the WHO criteria for severe malaria and, despite treatment with intravenous quinine and supportive ICU care, mortality was 28.5% (8\/28).<\/jats:p>\n                  <jats:p>The three pregnant patients died with 100% foetal mortality and the four paediatric patients survived. Of the non-survivors, 8\/8 developed ARDS (defined by worst ALI score &gt;2.5), 7\/8 developed shock requiring inotropic support and 7\/8 developed acute renal failure requiring CVVHD.<\/jats:p>\n                  <jats:p>Admission haemoglobin, platelet count, parasite count, and lowest Glasgow Coma Score in the first 24 hours were shown not to be predictors of mortality.<\/jats:p>","DOI":"10.1177\/0310057x9602400213","type":"journal-article","created":{"date-parts":[[2019,1,24]],"date-time":"2019-01-24T09:14:42Z","timestamp":1548321282000},"page":"217-223","source":"Crossref","is-referenced-by-count":33,"title":["Predictors of Mortality in Severe Malaria: A Two-Year Experience in a Non-Endemic Area"],"prefix":"10.1177","volume":"24","author":[{"given":"L.","family":"Blumberg","sequence":"first","affiliation":[{"name":"South African Institute of Medical Research and University of the Witwatersrand Hospital, South Africa"},{"name":"South African Institute of Medical Research and University of the Witwatersrand, South Africa."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R. 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