{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T11:31:49Z","timestamp":1777375909680,"version":"3.51.4"},"reference-count":27,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[1997,8,1]],"date-time":"1997-08-01T00:00:00Z","timestamp":870393600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Anaesth Intensive Care"],"published-print":{"date-parts":[[1997,8]]},"abstract":"<jats:p>A comparison between midazolam and midazolam-flumazenil for total intravenous anaesthesia in combination with topical anaesthesia and muscle relaxants was performed in a double-blind, parallel study in 40 patients scheduled for microlaryngoscopy with or without bronchoscopic procedures using jet ventilation with oxygen. A single intravenous injection of midazolam 0.3 mg\/kg, lignocaine spray and muscle relaxants provided adequate anaesthesia and good operative conditions throughout the procedures, which took 20 to 30 minutes.<\/jats:p>\n                  <jats:p>Patients who had placebo at the end of the procedures had a longer recovery and a high incidence of airway obstruction (20%). Administration of flumazenil provided prompt awakening in 19 of 20 patients (95%) within five minutes, resulting in rapid and favourable recovery without resedation or other side-effects, while only three of 20 (15%) patients in the placebo-treated group had improved consciousness within five minutes.<\/jats:p>\n                  <jats:p>The simplicity and reliability of the midazolam-flumazenil technique is attractive. We consider it worthy of further investigation for wider application in clinical practice.<\/jats:p>","DOI":"10.1177\/0310057x9702500406","type":"journal-article","created":{"date-parts":[[2019,1,14]],"date-time":"2019-01-14T13:37:20Z","timestamp":1547473040000},"page":"358-364","source":"Crossref","is-referenced-by-count":0,"title":["Midazolam-Flumazenil Topical Anaesthesia for Microlaryngoscopy with Jet Ventilation"],"prefix":"10.1177","volume":"25","author":[{"given":"W.","family":"Rushatamukayanunt","sequence":"first","affiliation":[{"name":"Department of Anaesthesiology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"Tritrakarn","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1997,8,1]]},"reference":[{"key":"bibr1-0310057X9702500406","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-6576.1990.tb03193.x"},{"key":"bibr2-0310057X9702500406","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-198711000-00015"},{"key":"bibr3-0310057X9702500406","doi-asserted-by":"publisher","DOI":"10.1213\/00000539-198212000-00007"},{"key":"bibr4-0310057X9702500406","first-page":"177","volume":"32","author":"Geptf E.","year":"1981","journal-title":"Acta Anesth Belgica"},{"key":"bibr5-0310057X9702500406","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2044.1987.tb03976.x"},{"key":"bibr6-0310057X9702500406","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1985.00800040091014"},{"key":"bibr7-0310057X9702500406","first-page":"117","volume":"43","author":"Versichelen 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