{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T19:27:41Z","timestamp":1778873261940,"version":"3.51.4"},"reference-count":13,"publisher":"SAGE Publications","issue":"7","license":[{"start":{"date-parts":[[2014,1,3]],"date-time":"2014-01-03T00:00:00Z","timestamp":1388707200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Cephalalgia"],"published-print":{"date-parts":[[2014,6]]},"abstract":"\n Background<\/jats:title>\n Migraine patients have an increased photic-driving response. This \u2018H-response\u2019 (HR) has potential diagnostic value but it is time consuming.<\/jats:p>\n <\/jats:sec>\n \n Aim<\/jats:title>\n The aim of the study was to establish a fast and standardized test for the study of migraine biology and treatment.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n We studied 11 migraine patients and 11 matched control participants. We used stroboscope flashes with a \u2018chirp\u2019-like linear frequency-increase from 10 to 40\u2009Hz. EEG was recorded from occipital electrodes. Power spectral density was calculated for the stimulus response and corrected for baseline. An HR-estimator was calculated as the average power between 18 and 26\u2009Hz in the stimulation-frequency window.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n There was a significant difference for single ( p\u2009<\u20090.05) and for 10 averaged recordings ( p\u2009<\u20090.01) between migraineurs and controls, and a high inter-test reliability (Cronbach\u2019s alpha\u2009=\u20090.94).<\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n Chirp-like stimulation to study the H-response is reliable and efficient and might therefore have a potential for acute interventional studies in migraine research.<\/jats:p>\n <\/jats:sec>","DOI":"10.1177\/0333102413517777","type":"journal-article","created":{"date-parts":[[2014,1,3]],"date-time":"2014-01-03T23:29:29Z","timestamp":1388791769000},"page":"554-558","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":13,"title":["Chirp stimulation: H-response short and dynamic"],"prefix":"10.1177","volume":"34","author":[{"given":"Andreas R","family":"Gantenbein","sequence":"first","affiliation":[{"name":"Headache and Pain Unit, Department of Neurology, University Hospital Zurich, Switzerland"},{"name":"RehaClinic Bad Zurzach, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter S","family":"Sandor","sequence":"additional","affiliation":[{"name":"RehaClinic Bad Zurzach, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter J","family":"Goadsby","sequence":"additional","affiliation":[{"name":"Headache Group, NIHR-Wellcome Trust Clinical Research Facility, King's College London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Holger","family":"Kaube","sequence":"additional","affiliation":[{"name":"Neurology and Headache Centre, M\u00fcnchnerFreiheit, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2014,1,3]]},"reference":[{"key":"bibr1-0333102413517777","doi-asserted-by":"publisher","DOI":"10.1016\/0013-4694(59)90052-5"},{"key":"bibr2-0333102413517777","doi-asserted-by":"publisher","DOI":"10.1177\/155005940003100206"},{"key":"bibr3-0333102413517777","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.45.7.1263"},{"key":"bibr4-0333102413517777","doi-asserted-by":"publisher","DOI":"10.1177\/0333102410385582"},{"key":"bibr5-0333102413517777","doi-asserted-by":"publisher","DOI":"10.1007\/s100720050006"},{"key":"bibr6-0333102413517777","doi-asserted-by":"publisher","DOI":"10.1016\/S1388-2457(00)00271-6"},{"key":"bibr7-0333102413517777","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1977.00500190037005"},{"key":"bibr8-0333102413517777","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4610.1979.hed1902063.x"},{"key":"bibr9-0333102413517777","doi-asserted-by":"publisher","DOI":"10.1016\/0753-3322(96)84716-0"},{"key":"bibr10-0333102413517777","doi-asserted-by":"publisher","DOI":"10.1016\/j.nlm.2008.09.012"},{"key":"bibr11-0333102413517777","doi-asserted-by":"publisher","DOI":"10.1103\/PhysRevLett.93.038103"},{"key":"bibr12-0333102413517777","doi-asserted-by":"publisher","DOI":"10.1097\/WNR.0b013e32835eba81"},{"key":"bibr13-0333102413517777","doi-asserted-by":"publisher","DOI":"10.1016\/S0304-3940(98)00811-8"}],"container-title":["Cephalalgia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0333102413517777","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0333102413517777","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0333102413517777","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T14:47:55Z","timestamp":1777387675000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0333102413517777"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,1,3]]},"references-count":13,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2014,6]]}},"alternative-id":["10.1177\/0333102413517777"],"URL":"https:\/\/doi.org\/10.1177\/0333102413517777","relation":{},"ISSN":["0333-1024","1468-2982"],"issn-type":[{"value":"0333-1024","type":"print"},{"value":"1468-2982","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,1,3]]}}}