{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T19:26:13Z","timestamp":1777490773345,"version":"3.51.4"},"reference-count":31,"publisher":"SAGE Publications","issue":"9","license":[{"start":{"date-parts":[[2014,2,5]],"date-time":"2014-02-05T00:00:00Z","timestamp":1391558400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Cephalalgia"],"published-print":{"date-parts":[[2014,8]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Headache is one of the most common symptoms after cocaine use.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We investigated headache frequency and characteristics and the correlation between headache and acute cocaine intake in a cross-sectional study in a consecutive series of chronic cocaine users.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Participation rate was 94.1%. Of the 80 subjects enrolled, 72 (90%) reported current headaches, in most cases migraine or probable migraine without aura. Of these 72, 29 (40.3%) had a headache history, whereas 43 (59.7%) reported de novo headache after beginning to use cocaine. After acute cocaine use, a large percentage of users reported headache attacks: 86.2% of previous headache sufferers (migraine or probable migraine without aura in all cases) and 93% of de novo headache sufferers (migraine\/probable migraine without aura\u2009=\u200935; episodic tension-type headache\u2009=\u2009three patients; cocaine-induced headache= two patients). Most subjects reported that when they used cocaine headaches worsened.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Chronic cocaine use frequently seems to worsen or induce headache with migraine or migraine-like characteristics, probably owing to a serotoninergic and dopaminergic system impairment. In headache sufferers, especially those with migraine headaches, clinicians should enquire into possible cocaine use.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0333102414520764","type":"journal-article","created":{"date-parts":[[2014,2,6]],"date-time":"2014-02-06T00:37:23Z","timestamp":1391647043000},"page":"671-678","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":9,"title":["Headache in chronic cocaine users: A cross-sectional study"],"prefix":"10.1177","volume":"34","author":[{"given":"Luisa","family":"Fofi","sequence":"first","affiliation":[{"name":"Headache and Pain Unit, Department of Neurological, Motor and Sensorial Sciences, IRCCS San Raffaele Pisana, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Valerio","family":"Orlandi","sequence":"additional","affiliation":[{"name":"Drug Addiction Service, 20th District, UOS Municipio 17, ASL RME, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicola","family":"Vanacore","sequence":"additional","affiliation":[{"name":"National Centre of Epidemiology, Surveillance and Health Promotion, National Institute of Health, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria C","family":"Mizzoni","sequence":"additional","affiliation":[{"name":"Drug Addiction Service, 20th District, UOS Municipio 17, ASL RME, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alba","family":"Rosa","sequence":"additional","affiliation":[{"name":"Drug Addiction Service, 20th District, UOS Municipio 17, ASL RME, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cinzia","family":"Aurilia","sequence":"additional","affiliation":[{"name":"Headache and Pain Unit, Department of Neurological, Motor and Sensorial Sciences, IRCCS San Raffaele Pisana, 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