{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T17:28:34Z","timestamp":1784654914759,"version":"3.55.0"},"reference-count":21,"publisher":"SAGE Publications","issue":"11","license":[{"start":{"date-parts":[[2015,1,28]],"date-time":"2015-01-28T00:00:00Z","timestamp":1422403200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Cephalalgia"],"published-print":{"date-parts":[[2015,10]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Visual aura is present in about one-third of migraine patients and triggering by bright or flickering lights is frequently reported.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>Using migraine with visual aura patients, we investigated the neurochemical profile of the visual cortex using magnetic resonance spectroscopy. Specifically, glutamate\/creatine and GABA\/creatine ratios were quantified in the occipital cortex of female migraine patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>GABA levels in the occipital cortex of migraine patients were lower than that of controls. Glutamate levels in migraine patients, but not controls, correlated with the blood-oxygenation-level-dependent (BOLD) signal in the primary visual cortex during visual stimulation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Migraine with visual aura appears to disrupt the excitation-inhibition coupling in the occipital cortex.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0333102414566860","type":"journal-article","created":{"date-parts":[[2015,1,29]],"date-time":"2015-01-29T00:39:40Z","timestamp":1422491980000},"page":"1025-1030","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":74,"title":["Altered neurochemical coupling in the occipital cortex in migraine with visual aura"],"prefix":"10.1177","volume":"35","author":[{"given":"Holly","family":"Bridge","sequence":"first","affiliation":[{"name":"Nuffield Department of Clinical Neuroscience, University of Oxford, UK"},{"name":"Oxford Centre for Functional MRI of the Brain (FMRIB), University of Oxford, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charlotte J","family":"Stagg","sequence":"additional","affiliation":[{"name":"Nuffield Department of Clinical Neuroscience, University of Oxford, UK"},{"name":"Oxford Centre for Functional MRI of the Brain (FMRIB), University of Oxford, UK"},{"name":"Oxford Centre for Human Brain Activity, University of Oxford, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jamie","family":"Near","sequence":"additional","affiliation":[{"name":"Douglas Mental Health University Institute and Department of Psychiatry, McGill University, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chi-ieong","family":"Lau","sequence":"additional","affiliation":[{"name":"Department of Neurology, Shin-Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aimee","family":"Zisner","sequence":"additional","affiliation":[{"name":"Oxford Centre for Functional MRI of the Brain (FMRIB), University of Oxford, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. Zameel","family":"Cader","sequence":"additional","affiliation":[{"name":"Nuffield Department of Clinical Neuroscience, University of Oxford, UK"},{"name":"Oxford Headache Centre, John Radcliffe Hospital, Oxford, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2015,1,28]]},"reference":[{"key":"bibr1-0333102414566860","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4610.2006.00585.x"},{"key":"bibr2-0333102414566860","doi-asserted-by":"crossref","unstructured":"Hougaard A, Amin FM, Hauge AW, et al. Provocation of migraine with aura using natural trigger factors.\n                      Neurology\n                      2013; 80: 428-431.","DOI":"10.1212\/WNL.0b013e31827f0f10"},{"key":"bibr3-0333102414566860","doi-asserted-by":"publisher","DOI":"10.1016\/j.tins.2012.04.007"},{"key":"bibr4-0333102414566860","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.071582498"},{"key":"bibr5-0333102414566860","doi-asserted-by":"publisher","DOI":"10.4161\/cib.16213"},{"key":"bibr6-0333102414566860","doi-asserted-by":"publisher","DOI":"10.1186\/1744-8069-5-34"},{"key":"bibr7-0333102414566860","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/bhr248"},{"key":"bibr8-0333102414566860","doi-asserted-by":"publisher","DOI":"10.1111\/head.12030"},{"key":"bibr9-0333102414566860","doi-asserted-by":"publisher","DOI":"10.1177\/0333102412452048"},{"key":"bibr10-0333102414566860","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.21961"},{"key":"bibr11-0333102414566860","doi-asserted-by":"publisher","DOI":"10.1002\/nbm.2960"},{"key":"bibr12-0333102414566860","doi-asserted-by":"crossref","unstructured":"Near J, Edden R, Evans CJ, et\u00a0al. Frequency and phase drift correction of magnetic resonance spectroscopy data by spectral registration in the time domain.\n                      Magn Reson Med\n                      . Epub ahead of print 16 January 2014. DOI: 10.1002\/mrm.25094.","DOI":"10.1002\/mrm.25094"},{"key":"bibr13-0333102414566860","doi-asserted-by":"publisher","DOI":"10.1109\/42.906424"},{"key":"bibr14-0333102414566860","doi-asserted-by":"publisher","DOI":"10.1152\/jn.91060.2008"},{"key":"bibr15-0333102414566860","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.4426-09.2009"},{"key":"bibr16-0333102414566860","doi-asserted-by":"publisher","DOI":"10.1002\/hbm.22361"},{"key":"bibr17-0333102414566860","doi-asserted-by":"publisher","DOI":"10.1001\/archgenpsychiatry.2009.39"},{"key":"bibr18-0333102414566860","doi-asserted-by":"publisher","DOI":"10.1038\/ng.2676"},{"key":"bibr19-0333102414566860","doi-asserted-by":"publisher","DOI":"10.1124\/jpet.109.153908"},{"key":"bibr20-0333102414566860","doi-asserted-by":"publisher","DOI":"10.1023\/A:1022393604014"},{"key":"bibr21-0333102414566860","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.58.3.368"}],"container-title":["Cephalalgia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0333102414566860","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0333102414566860","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0333102414566860","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T14:46:43Z","timestamp":1777387603000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0333102414566860"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,1,28]]},"references-count":21,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2015,10]]}},"alternative-id":["10.1177\/0333102414566860"],"URL":"https:\/\/doi.org\/10.1177\/0333102414566860","relation":{},"ISSN":["0333-1024","1468-2982"],"issn-type":[{"value":"0333-1024","type":"print"},{"value":"1468-2982","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,1,28]]}}}