{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T01:46:37Z","timestamp":1792806397575,"version":"4.5.0"},"reference-count":34,"publisher":"SAGE Publications","issue":"13","license":[{"start":{"date-parts":[[2016,7,19]],"date-time":"2016-07-19T00:00:00Z","timestamp":1468886400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Cephalalgia"],"published-print":{"date-parts":[[2016,11]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>\n                      To determine the proportion of patients with spontaneous intracranial hypotension (SIH) who had a cerebrospinal fluid (CSF) pressure &gt;6\u2009cm H\n                      <jats:sub>2<\/jats:sub>\n                      O and to investigate the clinical and imaging variables associated with CSF pressure ( P\n                      <jats:sub>CSF<\/jats:sub>\n                      ) in this condition.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      We retrospectively reviewed 106 patients with SIH. P\n                      <jats:sub>CSF<\/jats:sub>\n                      was measured by lumbar puncture prior to treatment. Clinical and imaging variables \u2013 including demographic data, brain imaging results, symptom duration, and abdominal circumference \u2013 were collected. Univariate and multivariate analyses were performed to determine the correlation of these variables with P\n                      <jats:sub>CSF<\/jats:sub>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Sixty-one percent of patients had a P\n                      <jats:sub>CSF<\/jats:sub>\n                      between 6 and 20\u2009cm H\n                      <jats:sub>2<\/jats:sub>\n                      O; only 34% had a P\n                      <jats:sub>CSF<\/jats:sub>\n                      \u22646\u2009cm H\n                      <jats:sub>2<\/jats:sub>\n                      O. The factors associated with increased P\n                      <jats:sub>CSF<\/jats:sub>\n                      included abdominal circumference ( p\u2009&lt;\u20090.001), symptom duration ( p\u2009=\u20090.015), and the absence of brain magnetic resonance imaging findings of SIH ( p\u2009=\u20090.003). A wide variability in P\n                      <jats:sub>CSF<\/jats:sub>\n                      was observed among all patients, which was not completely accounted for by the variables included in the model.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      Normal CSF pressure is common in patients with SIH; the absence of a low opening pressure should not exclude this condition. Body habitus, symptom duration, and brain imaging are correlated with P\n                      <jats:sub>CSF<\/jats:sub>\n                      measurements, but these factors alone do not entirely explain the wide variability in observed pressures in this condition and this suggests the influence of other factors.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0333102415623071","type":"journal-article","created":{"date-parts":[[2015,12,18]],"date-time":"2015-12-18T20:27:15Z","timestamp":1450470435000},"page":"1209-1217","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":142,"title":["How common is normal cerebrospinal fluid pressure in spontaneous intracranial hypotension?"],"prefix":"10.1177","volume":"36","author":[{"given":"Peter G","family":"Kranz","sequence":"first","affiliation":[{"name":"Department of Radiology, Duke University Medical Center, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teerath P","family":"Tanpitukpongse","sequence":"additional","affiliation":[{"name":"Department of Radiology, Duke University Medical Center, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kingshuk Roy","family":"Choudhury","sequence":"additional","affiliation":[{"name":"Department of Radiology, Duke University Medical Center, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timothy J","family":"Amrhein","sequence":"additional","affiliation":[{"name":"Department of Radiology, Duke University Medical Center, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linda","family":"Gray","sequence":"additional","affiliation":[{"name":"Department of Radiology, Duke University Medical Center, 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