{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T19:22:02Z","timestamp":1777490522767,"version":"3.51.4"},"reference-count":17,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2016,9,30]],"date-time":"2016-09-30T00:00:00Z","timestamp":1475193600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Cephalalgia"],"published-print":{"date-parts":[[2017,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background and aim<\/jats:title>\n                    <jats:p>Health administrators, policy makers, and educators have attempted to increase guideline adherence of migraine medications while reducing inappropriate use of opioid- and barbiturate-containing medications. We evaluated the burden of migraine and proportion of guideline-concordant care in a large, national health care system over time.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a time-series study using data from the Veterans Health Administration (VHA) electronic health record. Veterans with migraines were identified by ICD-9 code (346.X). Prescriptions and comorbid conditions were evaluated before and after migraine diagnosis. Chi-square tests and logistic regression were performed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 57,064 veterans were diagnosed with migraine headache (5.3%), with women significantly more likely diagnosed (11.6% vs. 4.4%, p\u2009&lt;\u20090.0001). The number of veterans diagnosed with migraine has significantly increased over the years. By 2012, triptans were prescribed to 43% of people with migraine, with no difference by gender. However, triptan prescriptions increased from 2004 to 2012 in men, but not women, veterans. Preventive medicines showed a significant increase with the year of migraine diagnosis, after controlling for age, sex, race, and for comorbidities treated with medications used for migraine prevention.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The burden of migraines is increasing within the VHA, with a corresponding increase in the delivery of guideline-concordant acute and prophylactic migraine-specific medication.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0333102416631959","type":"journal-article","created":{"date-parts":[[2016,2,25]],"date-time":"2016-02-25T23:44:23Z","timestamp":1456443863000},"page":"3-10","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":15,"title":["Increase in migraine diagnoses and guideline-concordant treatment in veterans, 2004\u20132012"],"prefix":"10.1177","volume":"37","author":[{"given":"HH","family":"Altalib","sequence":"first","affiliation":[{"name":"Pain Research, Informatics, Multimorbidities, and Education (PRIME) Center, VA Connecticut Healthcare System, USA"},{"name":"Yale University, Department of Neurology, USA"},{"name":"Yale University, Department of Psychiatry, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"BT","family":"Fenton","sequence":"additional","affiliation":[{"name":"Pain Research, Informatics, Multimorbidities, and Education (PRIME) Center, VA Connecticut Healthcare System, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J","family":"Sico","sequence":"additional","affiliation":[{"name":"Pain Research, Informatics, Multimorbidities, and Education (PRIME) Center, VA Connecticut Healthcare System, USA"},{"name":"Yale University, Department of Neurology, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"JL","family":"Goulet","sequence":"additional","affiliation":[{"name":"Pain Research, Informatics, Multimorbidities, and Education (PRIME) Center, VA Connecticut Healthcare System, USA"},{"name":"Yale University, Department of Psychiatry, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H","family":"Bathulapalli","sequence":"additional","affiliation":[{"name":"Pain Research, Informatics, Multimorbidities, and Education (PRIME) Center, VA Connecticut Healthcare System, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Mohammad","sequence":"additional","affiliation":[{"name":"Pain Research, Informatics, Multimorbidities, and Education (PRIME) Center, VA Connecticut Healthcare System, USA"},{"name":"Yale University, Department of Internal Medicine, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J","family":"Kulas","sequence":"additional","affiliation":[{"name":"Pain Research, Informatics, Multimorbidities, and Education (PRIME) Center, VA Connecticut Healthcare System, USA"},{"name":"Yale University, Department of Psychiatry, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Driscoll","sequence":"additional","affiliation":[{"name":"Pain Research, Informatics, Multimorbidities, and Education (PRIME) Center, VA Connecticut Healthcare System, USA"},{"name":"Yale University, Department of Psychiatry, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J","family":"Dziura","sequence":"additional","affiliation":[{"name":"Pain Research, Informatics, Multimorbidities, and Education (PRIME) Center, VA Connecticut Healthcare System, USA"},{"name":"Yale University, Department of Emergency Medicine, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K","family":"Mattocks","sequence":"additional","affiliation":[{"name":"VA Central Western Massachusetts Healthcare System, USA"},{"name":"University of Massachusetts Medical School, Department of Quantitative Health Science, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R","family":"Kerns","sequence":"additional","affiliation":[{"name":"Pain Research, Informatics, Multimorbidities, and Education (PRIME) Center, VA Connecticut Healthcare System, USA"},{"name":"Yale University, Department of Neurology, USA"},{"name":"Yale University, Department of Psychiatry, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C","family":"Brandt","sequence":"additional","affiliation":[{"name":"Pain Research, Informatics, Multimorbidities, and Education (PRIME) Center, VA Connecticut Healthcare System, USA"},{"name":"Yale University, Department of Emergency Medicine, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S","family":"Haskell","sequence":"additional","affiliation":[{"name":"Pain Research, Informatics, Multimorbidities, and Education (PRIME) Center, VA Connecticut Healthcare System, USA"},{"name":"Yale University, Department of Internal Medicine, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2016,9,30]]},"reference":[{"key":"bibr1-0333102416631959","first-page":"3S","volume":"118","author":"Lipton RB","year":"2005","journal-title":"Am J Med"},{"key":"bibr2-0333102416631959","doi-asserted-by":"publisher","DOI":"10.1016\/S0025-6196(11)60562-4"},{"key":"bibr3-0333102416631959","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.159.8.813"},{"key":"bibr4-0333102416631959","doi-asserted-by":"publisher","DOI":"10.1185\/030079902125001164"},{"key":"bibr5-0333102416631959","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-137-10-200211190-00014"},{"key":"bibr6-0333102416631959","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.55.6.754"},{"key":"bibr7-0333102416631959","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e3182535d20"},{"key":"bibr8-0333102416631959","doi-asserted-by":"publisher","DOI":"10.1016\/j.whi.2010.08.001"},{"key":"bibr9-0333102416631959","doi-asserted-by":"publisher","DOI":"10.1046\/j.1526-4610.2001.041007646.x"},{"key":"bibr10-0333102416631959","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-2982.2005.00988.x"},{"key":"bibr11-0333102416631959","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa072972"},{"key":"bibr12-0333102416631959","doi-asserted-by":"publisher","DOI":"10.1007\/s11606-014-3107-3"},{"key":"bibr13-0333102416631959","doi-asserted-by":"publisher","DOI":"10.1111\/head.12254"},{"key":"bibr14-0333102416631959","doi-asserted-by":"crossref","first-page":"1S","DOI":"10.1016\/j.amjmed.2005.07.010","volume":"118","author":"Lipton RB","year":"2005","journal-title":"Am J Med"},{"key":"bibr15-0333102416631959","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4610.2012.02265.x"},{"key":"bibr16-0333102416631959","doi-asserted-by":"publisher","DOI":"10.1177\/0333102412454944"},{"key":"bibr17-0333102416631959","doi-asserted-by":"publisher","DOI":"10.1046\/j.1526-4610.2003.03067.x"}],"container-title":["Cephalalgia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0333102416631959","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0333102416631959","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0333102416631959","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T14:47:18Z","timestamp":1777387638000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0333102416631959"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,9,30]]},"references-count":17,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017,1]]}},"alternative-id":["10.1177\/0333102416631959"],"URL":"https:\/\/doi.org\/10.1177\/0333102416631959","relation":{},"ISSN":["0333-1024","1468-2982"],"issn-type":[{"value":"0333-1024","type":"print"},{"value":"1468-2982","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,9,30]]}}}