{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T19:22:04Z","timestamp":1777490524377,"version":"3.51.4"},"reference-count":34,"publisher":"SAGE Publications","issue":"14","license":[{"start":{"date-parts":[[2016,7,11]],"date-time":"2016-07-11T00:00:00Z","timestamp":1468195200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Cephalalgia"],"published-print":{"date-parts":[[2016,12]]},"abstract":"<jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>The aim of this study was to evaluate the psychological factors associated with a negative outcome following detoxification in a 2-month follow-up in medication-overuse headache.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      All consecutive patients entering the detoxification program were analysed in a prospective, non-randomised fashion. Psychiatric conditions and personality characteristics were assessed using the Structured Clinical Interview for DSM-IV Disorders (SCID-I) and the Minnesota Multiphasic Personality Inventory (MMPI)-2. \u03c7\n                      <jats:sup>2<\/jats:sup>\n                      tests, one-way analyses of variance, and odds ratios (ORs) were used.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 248 patients completed the follow-up: 156 stopped overuse and their headaches reverted to an episodic pattern (Group A); 23 kept overusing without any benefit on headache frequency (Group B); and 51 stopped overuse without any benefit on headache frequency (Group C). The prognostic factors for the outcome of Group B were higher scores on the correction (OR 1.128; p\u2009=\u20090.036), depression (OR 1.071; p\u2009=\u20090.05), hysteria (OR 1.106; p\u2009=\u20090.023), and overcontrolled hostility (OR 1.182; p\u2009=\u20090.04) MMPI-2 scales, whereas those for Group C were psychiatric comorbidities (OR 1.502; p\u2009=\u20090.021) and higher scores on the hysteria scale (OR 1.125; p\u2009=\u20090.004).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The outcome of detoxification is influenced by psychological factors that should be considered when considering treatment strategies.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0333102416631960","type":"journal-article","created":{"date-parts":[[2016,2,15]],"date-time":"2016-02-15T23:04:01Z","timestamp":1455577441000},"page":"1356-1365","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":31,"title":["Psychological factors associated with failure of detoxification treatment in chronic headache associated with medication overuse"],"prefix":"10.1177","volume":"36","author":[{"given":"S","family":"Bottiroli","sequence":"first","affiliation":[{"name":"Headache Science Center and Headache Unit, National Neurological Institute C. Mondino, Pavia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Viana","sequence":"additional","affiliation":[{"name":"Headache Science Center and Headache Unit, National Neurological Institute C. Mondino, Pavia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G","family":"Sances","sequence":"additional","affiliation":[{"name":"Headache Science Center and Headache Unit, National Neurological Institute C. Mondino, Pavia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N","family":"Ghiotto","sequence":"additional","affiliation":[{"name":"Headache Science Center and Headache Unit, National Neurological Institute C. Mondino, Pavia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E","family":"Guaschino","sequence":"additional","affiliation":[{"name":"Headache Science Center and Headache Unit, National Neurological Institute C. Mondino, Pavia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F","family":"Galli","sequence":"additional","affiliation":[{"name":"Department of Health Sciences, University of Milan, Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E","family":"Vegni","sequence":"additional","affiliation":[{"name":"Department of Health Sciences, University of Milan, Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S","family":"Pazzi","sequence":"additional","affiliation":[{"name":"Headache Science Center and Headache Unit, National Neurological Institute C. Mondino, Pavia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G","family":"Nappi","sequence":"additional","affiliation":[{"name":"Headache Science Center and Headache Unit, National Neurological Institute C. 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Mondino, Pavia, Italy"},{"name":"Department of Brain and Behavioral Science, University of Pavia, Pavia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2016,7,11]]},"reference":[{"key":"bibr1-0333102416631960","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-2982.2005.00878.x"},{"key":"bibr2-0333102416631960","doi-asserted-by":"publisher","DOI":"10.1177\/0333102413485658"},{"key":"bibr3-0333102416631960","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-1331.2011.03497.x"},{"key":"bibr4-0333102416631960","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(04)00824-5"},{"key":"bibr5-0333102416631960","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-1331.2010.03157.x"},{"key":"bibr6-0333102416631960","doi-asserted-by":"publisher","DOI":"10.1007\/s10194-009-0159-6"},{"key":"bibr7-0333102416631960","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4610.2007.00971.x"},{"key":"bibr8-0333102416631960","doi-asserted-by":"publisher","DOI":"10.1177\/0333102412451363"},{"key":"bibr9-0333102416631960","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-2982.2009.01934.x"},{"key":"bibr10-0333102416631960","doi-asserted-by":"publisher","DOI":"10.1177\/0333102413477737"},{"key":"bibr11-0333102416631960","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-2982.1998.1807455.x"},{"key":"bibr12-0333102416631960","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-2982.2004.00758.x"},{"key":"bibr13-0333102416631960","doi-asserted-by":"crossref","unstructured":"Guidetti V, Galli F and Sheftell F. 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