{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T20:16:59Z","timestamp":1790367419216,"version":"4.1.0"},"reference-count":38,"publisher":"SAGE Publications","issue":"14","license":[{"start":{"date-parts":[[2016,9,29]],"date-time":"2016-09-29T00:00:00Z","timestamp":1475107200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Cephalalgia"],"published-print":{"date-parts":[[2016,12]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Reduced endothelial function is associated with elevated risk of cardiovascular disease, but evidence on the association between migraine and endothelial function is conflicting. The aim of this population-based study was to examine the relationship between flow-mediated dilatation (FMD) and migraine with aura, migraine without aura and tension-type headache.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In the third Nord-Tr\u00f8ndelag Healthy Study (HUNT3) FMD was measured by ultrasound during reactive hyperaemia of the brachial artery in a sample of 4739 healthy adult participants, 3929 of whom answered headache questions. The cross-sectional association between different headache diagnoses and FMD was evaluated by logistic regression, using a categorical approach.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Mean FMD did not differ between the headache groups and headache-free controls. In multi-adjusted analyses, no consistent association was found between FMD quintiles and headache groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>There was no relationship between FMD and migraine or other headache diagnoses in this large cross-sectional study of otherwise healthy respondents including freedom from pulmonary and cardiovascular diseases.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0333102416631961","type":"journal-article","created":{"date-parts":[[2016,2,11]],"date-time":"2016-02-11T20:08:07Z","timestamp":1455221287000},"page":"1341-1349","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":16,"title":["Migraine and endothelial function: The HUNT3 Study"],"prefix":"10.1177","volume":"36","author":[{"given":"Joakim Schj\u00f8lberg","family":"Larsen","sequence":"first","affiliation":[{"name":"Department of Neuroscience, Norwegian University of Science and Technology, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eli-Anne","family":"Skaug","sequence":"additional","affiliation":[{"name":"K.G. Jebsen Center of Exercise in Medicine, Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ulrik","family":"Wisl\u00f8ff","sequence":"additional","affiliation":[{"name":"K.G. Jebsen Center of Exercise in Medicine, Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Norway"},{"name":"Department of Cardiology, St. Olavs Hospital, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00d8yvind","family":"Ellingsen","sequence":"additional","affiliation":[{"name":"K.G. Jebsen Center of Exercise in Medicine, Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Norway"},{"name":"Department of Cardiology, St. Olavs Hospital, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lars Jacob","family":"Stovner","sequence":"additional","affiliation":[{"name":"Department of Neuroscience, Norwegian University of Science and Technology, Norway"},{"name":"Norwegian Advisory Unit on Headaches, St Olavs Hospital, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mattias","family":"Linde","sequence":"additional","affiliation":[{"name":"Department of Neuroscience, Norwegian University of Science and Technology, Norway"},{"name":"Norwegian Advisory Unit on Headaches, St Olavs Hospital, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Knut","family":"Hagen","sequence":"additional","affiliation":[{"name":"Department of Neuroscience, Norwegian University of Science and Technology, Norway"},{"name":"Norwegian Advisory Unit on Headaches, St Olavs Hospital, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2016,9,29]]},"reference":[{"key":"bibr1-0333102416631961","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(12)61729-2"},{"key":"bibr2-0333102416631961","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(15)60692-4"},{"key":"bibr3-0333102416631961","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2009.12.021"},{"key":"bibr4-0333102416631961","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.38302.504063.8F"},{"key":"bibr5-0333102416631961","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.b3914"},{"key":"bibr6-0333102416631961","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e3181d0cc8b"},{"key":"bibr7-0333102416631961","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.307.6899.289"},{"key":"bibr8-0333102416631961","doi-asserted-by":"publisher","DOI":"10.1001\/jama.296.3.283"},{"key":"bibr9-0333102416631961","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.167.8.795"},{"key":"bibr10-0333102416631961","doi-asserted-by":"publisher","DOI":"10.1186\/1129-2377-14-80"},{"key":"bibr11-0333102416631961","doi-asserted-by":"publisher","DOI":"10.1111\/head.12494"},{"key":"bibr12-0333102416631961","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-2982.2009.01937.x"},{"key":"bibr13-0333102416631961","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e31826170ce"},{"key":"bibr14-0333102416631961","doi-asserted-by":"publisher","DOI":"10.1536\/ihj.14-385"},{"key":"bibr15-0333102416631961","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2012.09.047"},{"key":"bibr16-0333102416631961","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2377-10-18"},{"key":"bibr17-0333102416631961","doi-asserted-by":"publisher","DOI":"10.1097\/00019501-200602000-00005"},{"key":"bibr18-0333102416631961","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4610.2007.00657.x"},{"key":"bibr19-0333102416631961","doi-asserted-by":"publisher","DOI":"10.1177\/0333102410390396"},{"key":"bibr20-0333102416631961","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4610.2006.00532.x"},{"key":"bibr21-0333102416631961","doi-asserted-by":"publisher","DOI":"10.1016\/j.jstrokecerebrovasdis.2009.04.007"},{"key":"bibr22-0333102416631961","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/dys095"},{"key":"bibr23-0333102416631961","doi-asserted-by":"publisher","DOI":"10.1177\/2047487312444234"},{"key":"bibr24-0333102416631961","doi-asserted-by":"publisher","DOI":"10.1249\/MSS.0b013e31820ca81c"},{"key":"bibr25-0333102416631961","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2288-12-143"},{"key":"bibr26-0333102416631961","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(01)01746-6"},{"key":"bibr27-0333102416631961","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1111\/j.1468-2982.2003.00824.x","volume":"24","author":"Headache Classification Committee of the International Headache Society","year":"2004","journal-title":"Cephalalgia"},{"key":"bibr28-0333102416631961","doi-asserted-by":"publisher","DOI":"10.1177\/0333102410391488"},{"key":"bibr29-0333102416631961","doi-asserted-by":"publisher","DOI":"10.1007\/s10194-009-0174-7"},{"key":"bibr30-0333102416631961","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-1331.2010.03199.x"},{"key":"bibr31-0333102416631961","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-2982.2007.01302.x"},{"key":"bibr32-0333102416631961","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0101371"},{"key":"bibr33-0333102416631961","doi-asserted-by":"crossref","unstructured":"Hagen K, Wisl\u00f8ff U, Ellingsen \u00d8, et\u00a0al. Headache and peak oxygen uptake: The HUNT3 study.\n                      Cephalalgia\n                      . 2016; 36: 437\u2013444.","DOI":"10.1177\/0333102415597528"},{"key":"bibr34-0333102416631961","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000260964.28393.ed"},{"key":"bibr35-0333102416631961","doi-asserted-by":"crossref","unstructured":"Gonzal\u00e9z-Quintanilla V, Toriello M, Palacio E, et\u00a0al. Systemic and cerebral endothelial dysfunction in chronic migraine. A case control-study with an active comparator.\n                      Cephalalgia\n                      . 2016; 36: 552\u2013560.","DOI":"10.1177\/0333102415607857"},{"key":"bibr36-0333102416631961","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2377-11-146"},{"key":"bibr37-0333102416631961","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp-2014-309571"},{"key":"bibr38-0333102416631961","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(95)00327-4"}],"container-title":["Cephalalgia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0333102416631961","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0333102416631961","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0333102416631961","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T14:47:18Z","timestamp":1777387638000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0333102416631961"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,9,29]]},"references-count":38,"journal-issue":{"issue":"14","published-print":{"date-parts":[[2016,12]]}},"alternative-id":["10.1177\/0333102416631961"],"URL":"https:\/\/doi.org\/10.1177\/0333102416631961","relation":{},"ISSN":["0333-1024","1468-2982"],"issn-type":[{"value":"0333-1024","type":"print"},{"value":"1468-2982","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,9,29]]}}}