{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T08:52:55Z","timestamp":1792659175280,"version":"4.5.0"},"reference-count":33,"publisher":"SAGE Publications","issue":"12","license":[{"start":{"date-parts":[[2016,7,11]],"date-time":"2016-07-11T00:00:00Z","timestamp":1468195200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Cephalalgia"],"published-print":{"date-parts":[[2016,10]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Migraine is one of the most disabling neurological disorders. The current pharmacological armamentarium is not satisfying for a large proportion of patients because the responder rate does not exceed 50% on average and the most effective drugs often induce intolerable side effects. During recent years, noninvasive central and peripheral neuromodulation methods have been explored for migraine treatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Overview<\/jats:title>\n                    <jats:p>A review of the available evidence suggests that noninvasive neuromodulation techniques could be beneficial for migraine patients. The transcranial stimulation methods allow modulating selectively cortical activity and can thus be curtailed to the patient\u2019s pathophysiological profile, while transcutaneous stimulation of pericranial nerves likely modulates central pain control centers. Occipital single-pulse transcranial magnetic stimulation and transcutaneous supraorbital stimulation have the strongest evidence respectively for acute and preventive treatment. Transcranial direct current stimulation and repetitive magnetic stimulation are promising in pilot studies, but large sham-controlled trials are not yet available.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The noninvasive neurostimulation methods are promising for migraine treatment and devoid of serious adverse effects allowing their combination with drug therapies. Their application in clinical practice will depend on the industry\u2019s capacity to develop portable and user-friendly devices, and on the scientists\u2019 capacity to prove their efficacy in randomized sham-controlled trials.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0333102416636022","type":"journal-article","created":{"date-parts":[[2016,3,29]],"date-time":"2016-03-29T21:18:42Z","timestamp":1459286322000},"page":"1170-1180","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":48,"title":["Noninvasive neurostimulation methods for migraine therapy: The available evidence"],"prefix":"10.1177","volume":"36","author":[{"given":"Jean","family":"Schoenen","sequence":"first","affiliation":[{"name":"Li\u00e8ge University, Headache Research Unit, University Department of Neurology, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Baschi","family":"Roberta","sequence":"additional","affiliation":[{"name":"Headache Center and Unit of Neurology and Neurophysiopathology, University of Palermo, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Delphine","family":"Magis","sequence":"additional","affiliation":[{"name":"Li\u00e8ge University, Headache Research Unit, University Department of Neurology, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gianluca","family":"Coppola","sequence":"additional","affiliation":[{"name":"G.B. Bietti Foundation IRCCS, Department of Neurophysiology of Vision and Neurophthalmology, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2016,7,11]]},"reference":[{"key":"bibr1-0333102416636022","author":"Coppola G","journal-title":"Cephalalgia"},{"key":"bibr2-0333102416636022","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2377-11-25"},{"key":"bibr3-0333102416636022","doi-asserted-by":"publisher","DOI":"10.1007\/s10194-006-0329-8"},{"key":"bibr4-0333102416636022","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(10)70054-5"},{"key":"bibr5-0333102416636022","doi-asserted-by":"publisher","DOI":"10.1186\/s10194-015-0535-3"},{"key":"bibr6-0333102416636022","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2004.08.008"},{"key":"bibr7-0333102416636022","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-2982.2009.01911.x"},{"key":"bibr8-0333102416636022","doi-asserted-by":"publisher","DOI":"10.1179\/1743132812Y.0000000045"},{"key":"bibr9-0333102416636022","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-013-7072-2"},{"key":"bibr10-0333102416636022","doi-asserted-by":"publisher","DOI":"10.1177\/0333102413515340"},{"key":"bibr11-0333102416636022","volume":"52","author":"Sasso D\u2019Elia T","year":"2012","journal-title":"Front Human Neurosci"},{"key":"bibr12-0333102416636022","doi-asserted-by":"publisher","DOI":"10.1177\/0333102411399349"},{"key":"bibr13-0333102416636022","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4610.2012.02141.x"},{"key":"bibr14-0333102416636022","first-page":"1003","volume":"95","author":"Auvichayapat P","year":"2012","journal-title":"J Med Assoc Thai"},{"key":"bibr15-0333102416636022","doi-asserted-by":"publisher","DOI":"10.1186\/1129-2377-14-23"},{"key":"bibr16-0333102416636022","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2014.12.018"},{"key":"bibr17-0333102416636022","doi-asserted-by":"publisher","DOI":"10.1177\/0333102410381142"},{"key":"bibr18-0333102416636022","doi-asserted-by":"publisher","DOI":"10.1177\/0333102412462642"},{"key":"bibr19-0333102416636022","doi-asserted-by":"publisher","DOI":"10.1177\/0333102414543331"},{"key":"bibr20-0333102416636022","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e3182825055"},{"key":"bibr21-0333102416636022","first-page":"2","volume":"86","author":"Schoenen J","year":"2015","journal-title":"Neurology"},{"key":"bibr22-0333102416636022","doi-asserted-by":"publisher","DOI":"10.1186\/1129-2377-14-95"},{"key":"bibr23-0333102416636022","doi-asserted-by":"publisher","DOI":"10.1186\/s10194-015-0551-3"},{"key":"bibr24-0333102416636022","first-page":"134","volume":"29","author":"G\u00e9rardy P","year":"2009","journal-title":"Cephalalgia"},{"key":"bibr25-0333102416636022","author":"D\u2019Ostilio K","year":"2015","journal-title":"American Acad Neurol"},{"key":"bibr26-0333102416636022","doi-asserted-by":"publisher","DOI":"10.1007\/s40122-015-0039-5"},{"key":"bibr27-0333102416636022","doi-asserted-by":"publisher","DOI":"10.1177\/0333102414524494"},{"key":"bibr28-0333102416636022","doi-asserted-by":"publisher","DOI":"10.1186\/s10194-015-0542-4"},{"key":"bibr29-0333102416636022","doi-asserted-by":"publisher","DOI":"10.1186\/s10194-015-0543-3"},{"key":"bibr30-0333102416636022","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-1331.2004.00867.x"},{"key":"bibr31-0333102416636022","doi-asserted-by":"publisher","DOI":"10.1111\/ene.12043"},{"key":"bibr32-0333102416636022","doi-asserted-by":"publisher","DOI":"10.1007\/s11916-011-0231-1"},{"key":"bibr33-0333102416636022","doi-asserted-by":"publisher","DOI":"10.1177\/0333102413477739"}],"container-title":["Cephalalgia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0333102416636022","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0333102416636022","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0333102416636022","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T14:47:19Z","timestamp":1777387639000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0333102416636022"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,7,11]]},"references-count":33,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2016,10]]}},"alternative-id":["10.1177\/0333102416636022"],"URL":"https:\/\/doi.org\/10.1177\/0333102416636022","relation":{},"ISSN":["0333-1024","1468-2982"],"issn-type":[{"value":"0333-1024","type":"print"},{"value":"1468-2982","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,7,11]]}}}