{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T19:22:36Z","timestamp":1777490556747,"version":"3.51.4"},"reference-count":16,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2016,7,11]],"date-time":"2016-07-11T00:00:00Z","timestamp":1468195200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Cephalalgia"],"published-print":{"date-parts":[[2017,3]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>It has been hypothesized that a constitutionally narrow cavernous sinus might predispose individuals to cluster headache. Cavernous sinus dimensions, however, have never been assessed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In this case\u2013control study, we measured the dimensions of the cavernous sinus, skull base, internal carotid and pituitary gland with high-resolution T2-weighted magnetic resonance imaging in 25 episodic, 24 chronic and 13 probable cluster headache patients, 8 chronic paroxysmal hemicrania patients and 22 headache-free controls. Dimensions were compared between groups, correcting for age, sex and transcranial diameter.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>On qualitative inspection, no relevant pathology or anatomic variants that were previously associated with cluster headache or chronic paroxysmal hemicranias were observed in the cavernous sinus or paracavernous structures. The left-to-right transcranial diameter at the temporal fossa level (mean\u2009\u00b1\u2009SD) was larger in the headache groups (episodic cluster headache: 147.5\u2009\u00b1\u20097.3\u2009mm, p\u2009=\u20090.044; chronic cluster headache: 150.2\u2009\u00b1\u20097.3\u2009mm, p\u2009&lt;\u20090.001; probable cluster headache: 146.0\u2009\u00b1\u20095.3\u2009mm, p\u2009=\u20090.012; and chronic paroxysmal hemicrania: 145.2\u2009\u00b1\u20099.4\u2009mm, p\u2009=\u20090.044) compared with controls (140.2\u2009\u00b1\u20098.0\u2009mm). After adjusting for transcranial diameter and correcting for multiple comparisons, there were no differences in the dimensions of the cavernous sinus and surrounding structures between headache patients and controls.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Patients with cluster headache or chronic paroxysmal hemicrania had wider skulls than headache-free controls, but the proportional dimensions of the cavernous sinus were similar.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0333102416640513","type":"journal-article","created":{"date-parts":[[2016,3,23]],"date-time":"2016-03-23T20:19:12Z","timestamp":1458764352000},"page":"208-213","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["The cavernous sinus in cluster headache \u2013 a quantitative structural magnetic resonance imaging study"],"prefix":"10.1177","volume":"37","author":[{"given":"Enrico B","family":"Arkink","sequence":"first","affiliation":[{"name":"Department of Radiology, Leiden University Medical Center, Leiden, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guus G","family":"Schoonman","sequence":"additional","affiliation":[{"name":"Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands"},{"name":"Department of Neurology, Elisabeth-TweeSteden Hospital, Tilburg, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jorine A","family":"van Vliet","sequence":"additional","affiliation":[{"name":"Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands"},{"name":"Department of Neurology, Slingeland Hospital, Doetinchem, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hannah S","family":"Bakels","sequence":"additional","affiliation":[{"name":"Department of Radiology, Leiden University Medical Center, Leiden, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marjolein AM","family":"Sneeboer","sequence":"additional","affiliation":[{"name":"Department of Radiology, Leiden University Medical Center, Leiden, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joost","family":"Haan","sequence":"additional","affiliation":[{"name":"Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands"},{"name":"Department of Neurology, Alrijne Hospital, Leiderdorp, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark A","family":"van Buchem","sequence":"additional","affiliation":[{"name":"Department of Radiology, Leiden University Medical Center, Leiden, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michel D","family":"Ferrari","sequence":"additional","affiliation":[{"name":"Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark C","family":"Kruit","sequence":"additional","affiliation":[{"name":"Department of Radiology, Leiden University Medical Center, Leiden, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2016,7,11]]},"reference":[{"key":"bibr1-0333102416640513","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/120.1.193"},{"key":"bibr2-0333102416640513","doi-asserted-by":"crossref","unstructured":"The International Classification of Headache Disorders, 3rd edition (beta version).\n                      Cephalalgia\n                      2013; 33: 629\u2013808.","DOI":"10.1177\/0333102413485658"},{"key":"bibr3-0333102416640513","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4610.1988.hed2809584.x"},{"key":"bibr4-0333102416640513","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-2982.2006.01106.x"},{"key":"bibr5-0333102416640513","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4610.1994.hed3403125.x"},{"key":"bibr6-0333102416640513","doi-asserted-by":"publisher","DOI":"10.1046\/j.1468-2982.1998.1803143.x"},{"key":"bibr7-0333102416640513","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4610.1990.hed3006350.x"},{"key":"bibr8-0333102416640513","doi-asserted-by":"publisher","DOI":"10.1097\/WCO.0b013e32832b4bb3"},{"key":"bibr9-0333102416640513","unstructured":"The International Classification of Headache Disorders: 2nd edition.\n                      Cephalalgia\n                      2004; 24(Suppl. 1): 9\u2013160."},{"key":"bibr10-0333102416640513","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-2982.2006.00932.x"},{"key":"bibr11-0333102416640513","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.61.5.721"},{"key":"bibr12-0333102416640513","first-page":"7","volume":"46","author":"Ekbom K","year":"1970","journal-title":"Acta Neurol Scand"},{"key":"bibr13-0333102416640513","doi-asserted-by":"publisher","DOI":"10.1007\/s10194-009-0129-z"},{"key":"bibr14-0333102416640513","volume-title":"Fundamentals of Biostatistics","author":"Rosner B","year":"2005"},{"key":"bibr15-0333102416640513","doi-asserted-by":"publisher","DOI":"10.1111\/j.2517-6161.1995.tb02031.x"},{"key":"bibr16-0333102416640513","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4610.1972.hed1104175.x"}],"container-title":["Cephalalgia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0333102416640513","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0333102416640513","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0333102416640513","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T14:47:23Z","timestamp":1777387643000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0333102416640513"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,7,11]]},"references-count":16,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2017,3]]}},"alternative-id":["10.1177\/0333102416640513"],"URL":"https:\/\/doi.org\/10.1177\/0333102416640513","relation":{},"ISSN":["0333-1024","1468-2982"],"issn-type":[{"value":"0333-1024","type":"print"},{"value":"1468-2982","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,7,11]]}}}