{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T19:24:10Z","timestamp":1777490650625,"version":"3.51.4"},"reference-count":31,"publisher":"SAGE Publications","issue":"10","license":[{"start":{"date-parts":[[2016,7,4]],"date-time":"2016-07-04T00:00:00Z","timestamp":1467590400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Cephalalgia"],"published-print":{"date-parts":[[2017,9]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To assess longitudinal changes in cerebral blood flow velocities (\u0394CBFVs) according to the clinical course of migraine.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We retrospectively included migraine patients with two or more attacks per month at baseline who were followed up within 2 years with transcranial Doppler in a tertiary headache clinic. \u0394CBFVs were analyzed in relation to clinical courses, defined as remission (0\u20131 headache days\/month), persistence (2\u201314\/month), or progression (\u226515\/month) in episodic migraine (EM), and conversion to EM (&lt;15\/month) and persistence (\u226515\/month) in chronic migraine (CM).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 166 patients (90 EM and 76 CM) were included. In EM, the remission group ( n\u2009=\u200930) showed a decrease in CBFV in the middle cerebral artery (MCA) and the basilar artery (BA). The progression group ( n\u2009=\u200910) showed increasing CBFVs in the bilateral MCAs. Patients with the persistence course ( n\u2009=\u200950) showed generally unchanged CBFVs. In CM, \u0394CBFVs decreased in the BA and increased in the posterior cerebral artery (PCA) after conversion to EM ( n\u2009=\u200961), whereas they remained unchanged in the persistence group ( n\u2009=\u200915). In all patients, % change in headache days was positively correlated with the %\u0394CBFVs of the bilateral MCAs and the BA.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>CBFV changes are associated with the different clinical courses of migraine. The association is more prominent in EM than CM.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0333102416658715","type":"journal-article","created":{"date-parts":[[2016,7,5]],"date-time":"2016-07-05T20:08:03Z","timestamp":1467749283000},"page":"927-937","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":13,"title":["Longitudinal changes in cerebral blood flow velocities in different clinical courses of migraine"],"prefix":"10.1177","volume":"37","author":[{"given":"Mi Ji","family":"Lee","sequence":"first","affiliation":[{"name":"Department of Neurology, Neuroscience Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Min Kyung","family":"Chu","sequence":"additional","affiliation":[{"name":"Department of Neurology, Kangnam Sacred Heart Hospital, Hallym University College of Medicine, Seoul, 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