{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T01:45:10Z","timestamp":1792806310261,"version":"4.5.0"},"reference-count":148,"publisher":"SAGE Publications","issue":"13","license":[{"start":{"date-parts":[[2018,7,10]],"date-time":"2018-07-10T00:00:00Z","timestamp":1531180800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Cephalalgia"],"published-print":{"date-parts":[[2019,11]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>The trigeminal ganglion is unique among the somatosensory ganglia regarding its topography, structure, composition and possibly some functional properties of its cellular components. Being mainly responsible for the sensory innervation of the anterior regions of the head, it is a major target for headache research. One intriguing question is if the trigeminal ganglion is merely a transition site for sensory information from the periphery to the central nervous system, or if intracellular modulatory mechanisms and intercellular signaling are capable of controlling sensory information relevant for the pathophysiology of headaches.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>An online search based on PubMed was made using the keyword \u201ctrigeminal ganglion\u201d in combination with \u201canatomy\u201d, \u201cheadache\u201d, \u201cmigraine\u201d, \u201cneuropeptides\u201d, \u201creceptors\u201d and \u201csignaling\u201d. From the relevant literature, further references were selected in view of their relevance for headache mechanisms. The essential information was organized based on location and cell types of the trigeminal ganglion, neuropeptides, receptors for signaling molecules, signaling mechanisms, and their possible relevance for headache generation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The trigeminal ganglion consists of clusters of sensory neurons and their peripheral and central axon processes, which are arranged according to the three trigeminal partitions V1\u2013V3. The neurons are surrounded by satellite glial cells, the axons by Schwann cells. In addition, macrophage-like cells can be found in the trigeminal ganglion. Neurons express various neuropeptides, among which calcitonin gene-related peptide is the most prominent in terms of its prevalence and its role in primary headaches. The classical calcitonin gene-related peptide receptors are expressed in non-calcitonin gene-related peptide neurons and satellite glial cells, although the possibility of a second calcitonin gene-related peptide receptor in calcitonin gene-related peptide neurons remains to be investigated. A variety of other signal molecules like adenosine triphosphate, nitric oxide, cytokines, and neurotrophic factors are released from trigeminal ganglion cells and may act at receptors on adjacent neurons or satellite glial cells.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The trigeminal ganglion may act as an integrative organ. The morphological and functional arrangement of trigeminal ganglion cells suggests that intercellular and possibly also autocrine signaling mechanisms interact with intracellular mechanisms, including gene expression, to modulate sensory information. Receptors and neurotrophic factors delivered to the periphery or the trigeminal brainstem can contribute to peripheral and central sensitization, as in the case of primary headaches. The trigeminal ganglion as a target of drug action outside the blood-brain barrier should therefore be taken into account.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0333102418786261","type":"journal-article","created":{"date-parts":[[2018,7,10]],"date-time":"2018-07-10T09:21:32Z","timestamp":1531214492000},"page":"1661-1674","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":156,"title":["Current understanding of trigeminal ganglion structure and function in headache"],"prefix":"10.1177","volume":"39","author":[{"given":"Karl","family":"Messlinger","sequence":"first","affiliation":[{"name":"Institute of Physiology and Pathophysiology, Friedrich-Alexander-University Erlangen-N\u00fcrnberg, Erlangen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew F","family":"Russo","sequence":"additional","affiliation":[{"name":"Department of Molecular Physiology and Biophysics, University of Iowa, Iowa City, IA, USA"},{"name":"Iowa VA Health Care System, Iowa City, IA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2018,7,10]]},"reference":[{"key":"bibr1-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1152\/jn.1993.69.5.1779"},{"key":"bibr2-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1007\/BF00309843"},{"key":"bibr3-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1007\/BF00188214"},{"key":"bibr4-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.1940.01210040002001"},{"key":"bibr5-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1002\/cne.901830114"},{"key":"bibr6-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1002\/cne.902500205"},{"key":"bibr7-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1964.00460240025003"},{"key":"bibr8-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1152\/jn.1965.28.4.682"},{"key":"bibr9-0333102418786261","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1970.32.3.0336"},{"key":"bibr10-0333102418786261","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1971.34.5.0630"},{"key":"bibr11-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1080\/01616412.2000.11740719"},{"key":"bibr12-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1002\/jemt.22204"},{"key":"bibr13-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1016\/0306-4522(92)90256-2"},{"key":"bibr14-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1002\/cne.21607"},{"key":"bibr15-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1007\/BF00222438"},{"key":"bibr16-0333102418786261","first-page":"27","volume":"50","author":"Bruska M","year":"1991","journal-title":"Folia Morphol"},{"key":"bibr17-0333102418786261","first-page":"475","volume":"183","author":"Glenn JA","year":"1993","journal-title":"J Anat"},{"key":"bibr18-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2202-13-143"},{"key":"bibr19-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1186\/1744-8069-6-89"},{"key":"bibr20-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(85)90027-7"},{"key":"bibr21-0333102418786261","first-page":"29","volume":"552","author":"Hanko J","year":"1986","journal-title":"Acta Physiol Scand Suppl"},{"key":"bibr22-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1038\/jcbfm.1989.31"},{"key":"bibr23-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainres.2014.11.031"},{"key":"bibr24-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1016\/S0301-0082(01)00021-1"},{"key":"bibr25-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1002\/cne.902230105"},{"key":"bibr26-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1111\/head.12371"},{"key":"bibr27-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1097\/00001756-199401120-00024"},{"key":"bibr28-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-8993(02)03927-6"},{"key":"bibr29-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1097\/00001756-199411000-00035"},{"key":"bibr30-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1016\/j.npep.2014.01.004"},{"key":"bibr31-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1016\/j.regpep.2009.02.002"},{"key":"bibr32-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2010.05.016"},{"key":"bibr33-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1002\/cne.23804"},{"key":"bibr34-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.08-07-02468.1988"},{"key":"bibr35-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.12-04-01135.1992"},{"key":"bibr36-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1016\/0143-4179(93)90006-V"},{"key":"bibr37-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2202-6-4"},{"key":"bibr38-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpain.2006.09.005"},{"key":"bibr39-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1038\/308653a0"},{"key":"bibr40-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1111\/j.1460-9568.2006.04742.x"},{"key":"bibr41-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1016\/j.npep.2008.01.002"},{"key":"bibr42-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1016\/S1385-299X(02)00188-5"},{"key":"bibr43-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M005604200"},{"key":"bibr44-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-6147(00)01555-8"},{"key":"bibr45-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1038\/30666"},{"key":"bibr46-0333102418786261","doi-asserted-by":"crossref","unstructured":"Eftekhari S, Gaspar RC, Roberts R, et\u00a0al. Localization of CGRP receptor components and receptor binding sites in rhesus monkey brainstem: A detailed study using in situ hybridization, immunofluorescence and autoradiography.\n                      J Comp Neurol\n                      2016; 524: 90\u2013118.","DOI":"10.1002\/cne.23828"},{"key":"bibr47-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1002\/cne.23828"},{"key":"bibr48-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2016.04.046"},{"key":"bibr49-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1002\/acn3.197"},{"key":"bibr50-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1111\/bph.13783"},{"key":"bibr51-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1111\/j.1529-8027.2012.00404.x"},{"key":"bibr52-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1046\/j.1468-2982.1997.1707785.x"},{"key":"bibr53-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1046\/j.1468-2982.2001.00161.x"},{"key":"bibr54-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1016\/S0169-328X(02)00329-7"},{"key":"bibr55-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1097\/00001756-200203250-00030"},{"key":"bibr56-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1016\/S0306-4522(03)00364-6"},{"key":"bibr57-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-0102(01)00323-6"},{"key":"bibr58-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.12-12-04854.1992"},{"key":"bibr59-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainres.2005.02.041"},{"key":"bibr60-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2015.09.011"},{"key":"bibr61-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2014.03.043"},{"key":"bibr62-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1177\/0333102415618615"},{"key":"bibr63-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1097\/j.pain.0000000000000808"},{"key":"bibr64-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1016\/S0047-6374(01)00358-X"},{"key":"bibr65-0333102418786261","doi-asserted-by":"publisher","DOI":"10.2319\/082308-444.1"},{"key":"bibr66-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.17-17-06611.1997"},{"key":"bibr67-0333102418786261","doi-asserted-by":"publisher","DOI":"10.3109\/10799893.2014.885049"},{"key":"bibr68-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2012.04.015"},{"key":"bibr69-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.16-24-07892.1996"},{"key":"bibr70-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2003.09.022"},{"key":"bibr71-0333102418786261","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2017.00163"},{"key":"bibr72-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1016\/S0035-3787(05)85120-3"},{"key":"bibr73-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1177\/0333102416630579"},{"key":"bibr74-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1111\/j.1460-9568.2006.04602.x"},{"key":"bibr75-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1007\/s00429-016-1190-4"},{"key":"bibr76-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainres.2010.09.004"},{"key":"bibr77-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.1989-06.2006"},{"key":"bibr78-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-8993(01)02645-2"},{"key":"bibr79-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1016\/S0304-3940(98)00774-5"},{"key":"bibr80-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2006.09.035"},{"key":"bibr81-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2005.06.029"},{"key":"bibr82-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1007\/s12035-008-8020-5"},{"key":"bibr83-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M800296200"},{"key":"bibr84-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1186\/s12990-015-0074-6"},{"key":"bibr85-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpain.2007.03.001"},{"key":"bibr86-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejphar.2010.06.008"},{"key":"bibr87-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1016\/S0306-4522(03)00388-9"},{"key":"bibr88-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1017\/S1740925X09990408"},{"key":"bibr89-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.6440-10.2011"},{"key":"bibr90-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.00465.2010"},{"key":"bibr91-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjp.0705711"},{"key":"bibr92-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4610.2007.00854.x"},{"key":"bibr93-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.5490-08.2009"},{"key":"bibr94-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1111\/j.1460-9568.2009.06702.x"},{"key":"bibr95-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1038\/nature02282"},{"key":"bibr96-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awr272"},{"key":"bibr97-0333102418786261","doi-asserted-by":"crossref","unstructured":"Denner AC, Vogler B, Messlinger K, et\u00a0al. Role of transient receptor potential ankyrin 1 receptors in rodent models of meningeal nociception \u2013 experiments in\u00a0vitro.\n                      Eur J Pain\n                      2017; 21: 843\u2013854.","DOI":"10.1002\/ejp.986"},{"key":"bibr98-0333102418786261","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2017.00336"},{"key":"bibr99-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1016\/j.molbrainres.2005.01.013"},{"key":"bibr100-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1186\/1744-8069-8-66"},{"key":"bibr101-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms8150"},{"key":"bibr102-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1177\/0333102417712719"},{"key":"bibr103-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1111\/head.12152"},{"key":"bibr104-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuropharm.2014.12.015"},{"key":"bibr105-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainres.2007.12.028"},{"key":"bibr106-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1016\/j.neulet.2010.01.074"},{"key":"bibr107-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1007\/s11302-017-9576-1"},{"key":"bibr108-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1007\/s11302-016-9521-8"},{"key":"bibr109-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-4159.2006.04161.x"},{"key":"bibr110-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1007\/s10194-012-0454-5"},{"key":"bibr111-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.23-03-00807.2003"},{"key":"bibr112-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M406659200"},{"key":"bibr113-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.4542-06.2007"},{"key":"bibr114-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1038\/35039526"},{"key":"bibr115-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1186\/1744-8069-5-43"},{"key":"bibr116-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-4159.2005.03524.x"},{"key":"bibr117-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1161\/01.RES.0000100067.62876.50"},{"key":"bibr118-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1177\/0333102410375725"},{"key":"bibr119-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1186\/1129-2377-14-74"},{"key":"bibr120-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1016\/j.neulet.2016.09.041"},{"key":"bibr121-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1111\/j.1460-9568.2012.08260.x"},{"key":"bibr122-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1002\/ana.23873"},{"key":"bibr123-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms5381"},{"key":"bibr124-0333102418786261","doi-asserted-by":"crossref","unstructured":"Dux M, Will C, Vogler B, et\u00a0al. Meningeal blood flow is controlled by H2 S-NO crosstalk activating HNO-TRPA1-CGRP signalling.\n                      Br J Pharmacol\n                      2015; 173: 431\u2013445.","DOI":"10.1111\/bph.13164"},{"key":"bibr125-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-4159.2004.02833.x"},{"key":"bibr126-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1177\/0333102417691762"},{"key":"bibr127-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1016\/j.mcn.2010.10.005"},{"key":"bibr128-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-1838(99)00024-7"},{"key":"bibr129-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1186\/1129-2377-14-74"},{"key":"bibr130-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1016\/j.pharmthera.2005.06.015"},{"key":"bibr131-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdsr.2017.01.003"},{"key":"bibr132-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0068312"},{"key":"bibr133-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainres.2011.11.058"},{"key":"bibr134-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1038\/cr.2011.29"},{"key":"bibr135-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2014.10.019"},{"key":"bibr136-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpain.2013.03.010"},{"key":"bibr137-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1186\/1129-2377-15-7"},{"key":"bibr138-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-4159.2006.04161.x"},{"key":"bibr139-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1155\/2016\/9857201"},{"key":"bibr140-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1016\/j.neulet.2007.03.061"},{"key":"bibr141-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-pharmtox-010814-124701"},{"key":"bibr142-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1111\/bcp.12618"},{"key":"bibr143-0333102418786261","doi-asserted-by":"crossref","unstructured":"DosSantos MF, Holanda-Afonso RC, Lima RL, et\u00a0al. The role of the blood\u2013brain barrier in the development and treatment of migraine and other pain disorders.\n                      Front Cell Neurosci\n                      2014; 8: 302. doi: 10.3389\/fncel.2014.00302. eCollection 20148.","DOI":"10.3389\/fncel.2014.00302"},{"key":"bibr144-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1002\/cne.21607"},{"key":"bibr145-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M800296200"},{"key":"bibr146-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.6440-10.2011"},{"key":"bibr147-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1111\/j.1460-9568.2006.04742.x"},{"key":"bibr148-0333102418786261","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdsr.2017.01.003"}],"container-title":["Cephalalgia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0333102418786261","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0333102418786261","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0333102418786261","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T14:47:59Z","timestamp":1777387679000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0333102418786261"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,7,10]]},"references-count":148,"journal-issue":{"issue":"13","published-print":{"date-parts":[[2019,11]]}},"alternative-id":["10.1177\/0333102418786261"],"URL":"https:\/\/doi.org\/10.1177\/0333102418786261","relation":{},"ISSN":["0333-1024","1468-2982"],"issn-type":[{"value":"0333-1024","type":"print"},{"value":"1468-2982","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,7,10]]}}}